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| 1 | Potential antibacterial activity of berberine against multi drug resistant enterovirulent Escherichia coli isolated from yaks(Poephagus grunniens) with haemorrhagic diarrhoea显示文摘Objective:To evaluate the antimicrobial efficacy of berberine,a plant alkaloid.Methods:Five multi-drug resistant(MDR) STEC/EPEC and five MDR ETEC isolates from yaks with haemorrhagic diarrhoea were selected for the study.Antibacterial activity of berberine was evaluated by broth dilution and disc diffusion methods.The binding kinetics of berberine to DNA and protein was also enumerated.Results:For both categories of enterovirulent Escherichia coli(E.roli) isolates, berberine displayed the antibaclerial effect in a dose dependent manner.The MIC50 of berberine chloride for STEC/EPEC isolates varied from 2.07μM to 3.6μM with a mean of(2.95±0.33)μM where as for ETEC strains it varied from 1.75 to 1.96μM with a mean of(1.87±0.03)μM. Berberine bind more tightly with double helix DNA with Bmax and Kd of(24.68±2.62) and(357.8±57.8),respectively.Berberine reacted with protein in comparatively loose manner with Bmax and Kd of(18.9±3.83) and <286.2±113.6),respectively.Conclusions:The results indicate clearly that berberine may serve as a good antibacterial against multi drug resistant E.coli. | Samiran Bandyopadhyay Pabitra H Patra Achintya Mahanti Dipak K Mondal Premanshu Dandapat Subhasis Bandyopadhyay Indranil Samanta Chandan Lodh Asit K Bera Debasish Bhattacharyya Mihir Sarkar Kishore K Baruah | 2013 | Asian Pacific Journal of Tropical Medicine2013，6，4： | 11 |
| 2 | Aggregate-protected and unprotected organic pools in conventional and no-tillage soils显示文摘 | BERAE M H HENDRIX P F COLEMAN D C | 1994 | Soil Science Society of American Journal1994，58，： | 1 |
| 3 | Seroindeterminate patterns and to human T - lymphotropic virus type I positivity in blood donors from Martinique, French West Indies 显示文摘 | C~saire R Bera O Maier H | 1999 | Transfu- sion1999，39，10： | 1 |
| 4 | Coassembly of a hexagonal columnar liquid crystalline superlattice from polymer(s) coated with a three-cylindrical bundle supramolecular dendrimer 显示文摘 | Percec V Ahn C H Bera T K | 1999 | Chem Eur J1999，5，： | 1 |
| 5 | Validation of multiclass urbantravel forecastingmodels combining origin-destination, mode and route choices显示文摘 | Boyce D Bera H | 2003 | Journal of Regional Science2003，43，3： | 1 |
| 6 | A structure-activity rela tionship study of 1,2,4-triazoloEl, 3,51 triazin-5,7-dione and its 5-thioxo analogues on anti-thymidine phosphorylase and associated anti-angio- genic activities显示文摘 | Bera H Tan BJ Sun L | 2013 | Eur J Med Chem2013，，67： | 1 |
| 7 | Microwave plasma nitridation of silicon dioxide on strained Si显示文摘 | Banerjee H D Ray S K | 1998 | Appl Phys Lett1998，73，11： | 1 |
| 8 | High-grade plasmablastic neoplasm of humerus in an HIV-negative patient,which was indeterminate between plasmablastic lymphoma and plasmablastic myeloma显示文摘 | Mondal SK Bera H Biswas PK etal | 2011 | J Can Res Ther2011，7，2： | 1 |
| 9 | Effects of Design and Op- erating Variables on Process Characteristics in a Meth- ane Discharge: a Numerical Study 显示文摘 | Bera K Farouk B Lee Y H | 2001 | Plasma Sources Science and Technology2001，10，2： | 1 |
| 10 | Cu_2S-deposited mesoporous NiO photocathode for a solar cell显示文摘 | Rhee J H Lee Y H Bera P | 2009 | Chem Phys Lett2009，477，46： | 1 |
| 11 | Interest-Rate Volatility,Basis Risk and Heteroskedasticity in Hedging Mortgages显示文摘 | Park H Y A K Bera | 1987 | Journal of American Real Estate and Urban Economic Analysis1987，15，2： | 1 |
| 12 | High efficiency photoluminescence from silica-coated CdSe quantum dots显示文摘 | Qian L Bera D Holloway P H | 2009 | Appl Phys Lett2009，，： | 1 |
| 13 | A modified form of diphthamide causes immunotoxin resistance in a lymphoma cell line with a deletion of the WDR85 gene显示文摘 | Wei H Bera TK Wayne AS | 2013 | J Biol Chem2013，288，12： | 1 |
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