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	题名	作者	年代	出处	被引量
1	Different profiles of cytokine expression during mild and severe acute pancreatitis显示文摘AIM:To study secretion patterns of proand anti-in-flammatory cytokines, and activation of various cellular subsets of leukocytes in peripheral blood.METHODS: We have conducted a prospective obser-vational study. One hundred and eight patients with a diagnosis of acute pancreatitis and onset of the disease within last 72 h were included in this study. The mRNA expression of 25 different types of cytokines in white blood cells was determined by quantitative real time polymerase chain reaction. Levels of 8 different cytokines in blood serum were measured by enzymelinked immunosorbent assay. Clinical data and cytokine expression results were subjected to statistical analysis.RESULTS: Severe and necrotizing acute pancreatitis (AP) is characterized by the significant depletion of circulating lymphocytes. Severe acute pancreatitis is as-sociated with a typical systemic inflammatory response syndrome and over-expression of pro-inflammatory cy-tokines [interleukin (IL)-6, IL-8, macrophage migration inhibitory factor (MIF)]. Serum IL-6 and MIF concentra-tions are the best discriminators of severe and necrotiz-ing AP as well as possible fatal outcome during the early course of the disease. CONCLUSION: Deregulation of cellular immune sys-tem is a key event leading to severe and necrotizing AP. IL-6 and MIF could be used as early predictors of complications.	Zilvinas Dambrauskas Nathalia Giese Antanas Gulbinas Thomas Giese Pascal O Berberat Juozas Pundzius Giedrius Barauskas Helmut Friess	2010	World Journal of Gastroenterology2010，16，15：	49
2	Fast Track—Different Implications in Pancreatic Surgery显示文摘	P. O. Berberat H. Ingold A. Gulbinas J. Kleeff M. W. Müller C. Gutt M. Weigand H. Friess M. W. Büchler	2007	Journal of Gastrointestinal Surgery2007，，：	2
3	The clinical relevance of posttraumatic avascular necrofis of the humeral head显示文摘	Gerber C Hersche O Berberat C	1998	J Shoulder Elbow Surg1998，7，：	1
4	Reduced KAI1 expression in pancreatic cancer is associated with lymph node and distant metastases 显示文摘	Friess H Guo XZ Berberat P	1998	int J Cancer1998，79，4：	1
5	Reduced KAI1 expression in pancreatic cancer is associated with lymph node and distant metastases显示文摘	Friess H Guo XZ Berberat P	1998	Int J Cancer1998，79，4：	1
6	The clinical relevance of posttraumatic avascular necrosis of the humeral head 显示文摘	Gerber C Hersche O Berberat C	1998	J Shoulder Elbow Surg1998，7，6：	1
7	The clinical relevance of posttrau- matic avascular necrosis of the humeral head 显示文摘	Gerber C Hersche O Berberat C	1998	J Shoulder Elbow Surg1998，6，：	1
8	Heme oxygenase-1-derived carbon monoxide requires the activation of transcription factor NF-кB to protect endothelial cell from tumor necrosis factor-or-mediated apoptosis显示文摘	Brouard S Berberat PO Tobiasch E	2002	J Biol Chem2002，277，17：	1
9	Fast track--different implications in pancreatic surgery显示文摘	Berberat PO Ingold H Gulbinas A	2007	J Gastrointest Surg2007，11，7：	1
10	Inhibition of heme oxygenase-1 increases responsiveness of pancreatic cancer cells to anticancer treatment 显示文摘	BERBERAT P O DAMBRAUSKAS Z GULBINAS A	2005	Clin Cancer Res2005，11，10：	1
11	The clinical relevance of posttraumatic avascular necrosis of the humeral head 显示文摘	Gerber C Hersche O Berberat C	1998	J Shoulder Elbow Surg1998，7，6：	1
12	Comparative analysis of galectins in primary tumors and tumor metastasis in human pancreatic cancer显示文摘	Berberat PO Friess H Wang L	2001	J Histochem Cytochem2001，49，4：	1
13	Heme oxygenase-l-derived carbon monoxide requires the activation of transcription factor NF-kappa B to protect endothelial cells from tumor necrosis factor-alpha-mediated apoptosis显示文摘	BROUARD S BERBERAT PO TOBIASCH E	2002	J Biol Chem2002，277，17：	1
14	Heme oxygenase-1- generated biliverdin ameliorates experimental murine colitis 显示文摘	Berberat P O A-Rahim Y I Yamashita K	2005	Inflamm Bowel Dis2005，11，：	1
15	Induction and expression of βig-h3 in pancreatic cancer cells显示文摘	Schneider D Kleeff J Berberat PO	2002	Biochim Biophys Acta2002，1588，1：	1
16	The clinical rele- vance of posttraumatic avascular necrosis of the humeral head 显示文摘	Gerber C Hersche O Berberat C	1998	J Shoulder Elbow Surg1998，7，6：	1
17	Reduced KAI1expression in pancreatic cancer is associated withlymph node and distant metastasis显示文摘	GUO X BERBERAT P	1998	Int J Cancer1998，79，3：	1
18	Carbon monoxide protects pancreatic beta -cells from apoptosis and improves islet function/survival after transplantation显示文摘	Gunther L Berberat PO Haga M	2002	Diabetes2002，51，4：	1
19	Pancreatic cancer-new aspects of molecular biology research 显示文摘	Kleeff J Friess H Berberat PO	2000	Sziss Surg2000，6，5：	1
20	Prevention and treatment of complications in pancreatic surgery显示文摘	Berberat PO Friess H Kleff J	1999	DigSurg1999，16，4：	1

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