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| 1 | Induction of sterilizing immunity against West Nile virus (WNV), by immunization with WNV-like particles produced in insect cells 显示文摘 | Qiao M Ashok M Bernard KA | 2004 | J Infect Dis2004，190，12： | 1 |
| 2 | Functional analysis of mosquito-borne flavivirus conserved sequence elements within 3'untranslated region of West Nile virus by use of a reporting replicon that differentiates between viral translation and RNA replication 显示文摘 | Lo MK Tilgner M Bernard KA | 2003 | J Virol2003，77，10： | 1 |
| 3 | Functional analysis of mosquito-borne flavivirus conserved sequence elements within 3'untranslated region of West Nile virus by use of a reporting replicon that differentiates between viral translation and RNA replication显示文摘 | Lo MK Tilgner M Bernard KA | 2003 | J Virol2003，77，10： | 1 |
| 4 | Characteristics of rare or recently described corynebacterium species recovered from human clinical material in Canada显示文摘 | Bernard KA Munro C Wiebe D | 2002 | J Clin Microbiol2002，40，11： | 1 |
| 5 | Cutaneous diphtheria inthe urban poor population of Vancouver, British Columbia,Canada:a 10-year review显示文摘 | Lowe CF Bernard KA?Romney MG | 2011 | Clin Microbiol?2011，49，7： | 1 |
| 6 | West Nile virus infection in birds and mosquitoes, New York State, 2000 显示文摘 | Maffei JG Jones SA | 2001 | Emerg Infect Dis2001，7，4： | 1 |
| 7 | Folate, Vitamin B6, and B12 Intakes in Relation to Risk of Stroke Among Men显示文摘 | Ka He Anwar Merchant Eric B. Rimm Bernard A. Rosner Meir J. Stampfer Walter C. Willett Alberto Ascherio | 2004 | Stroke: Journal of the American Heart Association2004，，1： | 1 |
| 8 | Functional analysis of mosquito-borne flavivirus conserved sequence elements within 3' untranslated region of West Nile virus by use of a reporting replicon that differentiates between viral translation and RNA replication显示文摘 | LO MK TILGNER M BERNARD KA | 2003 | J Virol2003，77，10： | 1 |
| 9 | Most Co rynebacterium xerosis strains identified in the routine clinical laboratory correspond to Corynebacterium amycolatum显示文摘 | G Funke PA Lawson KA Bernard | 1996 | J Clin Microbiol1996，34，5： | 1 |
| 10 | Sequence and cognitive analyses of two virulence-associated markers of bluetonge virus serotype 17 显示文摘 | Bernard KA Israel BA Wilson WC | 1997 | Intervirology1997，40，： | 1 |
| 11 | A machine learning model for colorectal liver metastasis post-hepatectomy prognostications显示文摘Background:Currently,surgical resection is the mainstay for colorectal liver metastases(CRLM)management and the only potentially curative treatment modality.Prognostication tools can support patient selection for surgical resection to maximize therapeutic benefit.This study aimed to develop a survival prediction model using machine learning based on a multicenter patient sample in Hong Kong.Methods:Patients who underwent hepatectomy for CRLM between 1 January 2009 and 31 December 2018 in four hospitals in Hong Kong were included in the study.Survival analysis was performed using Cox proportional hazards(CPH).A stepwise selection on Cox multivariable models with Least Absolute Shrinkage and Selection Operator(LASSO)regression was applied to a multiply-imputed dataset to build a prediction model.The model was validated in the validation set,and its performance was compared with that of Fong Clinical Risk Score(CRS)using concordance index.Results:A total of 572 patients were included with a median follow-up of 3.6 years.The full models for overall survival(OS)and recurrence-free survival(RFS)consist of the same 8 established and novel variables,namely colorectal cancer nodal stage,CRLM neoadjuvant treatment,Charlson Comorbidity Score,pre-hepatectomy bilirubin and carcinoembryonic antigen(CEA)levels,CRLM largest tumor diameter,extrahepatic metastasis detected on positron emission-tomography(PET)-scan as well as KRAS status.Our CRLM Machine-learning Algorithm Prognostication model(CMAP)demonstrated better ability to predict OS(C-index=0.651),compared with the Fong CRS for 1-year(C-index=0.571)and 5-year OS(C-index=0.574).It also achieved a C-index of 0.651 for RFS.Conclusions:We present a promising machine learning algorithm to individualize prognostications for patients following resection of CRLM with good discriminative ability. | Cynthia Sin Nga Lam Alina Ashok Bharwani Evelyn Hui Yi Chan Vernice Hui Yan Chan Howard Lai Ho Au Margaret Kay Ho Shireen Rashed Bernard Ming Hong Kwong Wentao Fang Ka Wing Ma Chung Mau Lo Tan To Cheung | 2023 | Hepatobiliary Surgery and Nutrition2023，12，4： | 0 |
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