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| 1 | Characterization of functional biliary pain and dyspeptic symptoms in patients with sphincter of Oddi dysfunction:Effect of papillotomy显示文摘AIM: To characterize functional biliary pain and other gastrointestinal (GI) symptoms in postcholecystectomy syndrome (PCS) patients with and without sphincter of Oddi dysfunction (SOD) proved by endoscopic sphincter of Oddi manometry (ESOM), and to assess the post- endoscopic sphincterotomy (EST) outcome. METHODS: We prospectively investigated 85 cholecystectomized patients referred for ERCP because of PCS and suspected SOD. On admission, all patients completed our questionnaire. Physical examination, laboratory tests, abdominal ultrasound, quantitative hepatobiliary scintigraphy (QHBS), and ERCP were performed in all patients. Based on clinical and ERCP findings 15 patients had unexpected bile duct stone disease and 15 patients had SOD biliary typeⅠ. ESOM demonstrated an elevated basal pressure in 25 patients with SOD biliary-type Ⅲ. In the remaining 30 cholecystectomized patients without SOD, the liver function tests, ERCP, QHBS and ESOM were all normal. As a control group, 30 ‘asymptomatic’ cholecystectomized volunteers (attended to our hospital for general cardiovascular screening) completed our questionnaire, which is consisted of 50 separate questions on GI symptoms and abdominal pain characteristics. Severity of the abdominal pain (frequency and intensity) was assessed with a visual analogue scale (VAS). In 40 of 80 patients having definite SOD (i.e. patients with SOD biliary typeⅠand those with elevated SO basal pressure on ESOM), an EST was performed just after ERCP. In these patients repeated questionnaires were filled at each follow-up visit (at 3 and 6 mo) and a second lookQHBS was performed 3 mo after the EST to assess the functional response to EST. RESULTS: The analysis of characteristics of the abdominal pain demonstrated that patients with common bile duct stone and definite SOD had a significantly higher score of symptomatic agreement with previously determined biliary-like pain features than patient groups of PCS without SOD and controls. In contrary, no significant differences were found when the pain severity scores were compared in different groups of PCS patients. In patients with definite SOD, EST induced a significant acceleration of the transpapillary bile flow; and based on the comparison of VASs obtained from the pre- and post-EST questionnaires, the severity scores of abdominal pain were significantly improved, however, only 15 of 35 (43%) patients became completely pain free. Post-EST severity of abdominal pain by VASs was significantly higher in patients with predominant dyspepsia at initial presentation as compared to those without dyspeptic symptoms. CONCLUSION: Persistent GI symptoms and general patient dissatisfaction is a rather common finding after EST in patients with SOD, and correlated with the presence of predominant dyspeptic symptoms at the initial presentation, but does not depend on the technical and functional success of EST. | László Madácsy Roland Fejes Gábor Kurucsai Ildikó Joó András Székely Viktória Bertalan Attila Szepes János Lonovics | 2006 | World Journal of Gastroenterology2006，12，42： | 33 |
| 2 | Progress in Interface Modifications from Compatibilization to Adaptive and Smart Interphases显示文摘 | Keszei S Mark S Bertalan G | 2005 | Europ Polym2005，41，4： | 1 |
| 3 | Progress in interface modifications: From compatibilization to adaptive and smart interphases 显示文摘 | Keszei S Mmtks S Bertalan G | 2005 | Eur Polym J2005，41，4： | 1 |
| 4 | Development of a MATLAB Based Bioprocess Simulation Tool显示文摘 | Sevella B Bertalan G | 2000 | Bioprocess Engineering2000，，23： | 1 |
| 5 | Progress in Inter- face Modifications: from Compatibilization to Adaptive and Smart Interphases 显示文摘 | Keszei S Matko S Bertalan G | 2005 | European Polymer Journal2005，41，4： | 1 |
| 6 | Role of Interface Modification in Filled and Flame-retarded Polymer Systems显示文摘 | Bertalan G Marosi G Anna P | 2001 | Solid State Lonies2001，，： | 1 |
| 7 | Development of a MATLAB based bioprocess simulation tool显示文摘 | Sevella B Bertalan G | 2000 | Bioprocess Engineering2000，，23： | 1 |
| 8 | Quantitative determination of the platinum-group elements and gold using NiS fire assay with laser ablation-inductively coupled plasma-mass spectrometry ( LA-ICP-MS ) 显示文摘 | Jarvis K E Williams J G Parry S J Bertalan E | 1995 | Chemical Geology1995，124，12： | 1 |
| 9 | Effect of Interface Modification on the Photo-stability of Pigmented Polyethy- lene Films显示文摘 | Anna P Bertalan G Marosi G | 2001 | Polymer Degradation and Stability2001，73，3： | 1 |
| 10 | Progress in interface modifications: from compatibilization to adaptive and smart interphases显示文摘 | KESZEI S MATKS S BERTALAN G | 2005 | European Polymer Journal2005，41，4： | 1 |
| 11 | Modified interface sin muhicomponent polypropylene fibers 显示文摘 | Marosi G Tohl A Bertalan G | 1998 | Composites Part A1998，29，： | 1 |
| 12 | Modified interfaces in multicomponent polypropylene fibers显示文摘 | MAROSI G TOHL A BERTALAN G | 1998 | Composites Part A:Applied Science and Manufacturing1998，29，： | 1 |
| 13 | Development of a MATLAB based bioprocess simulation tool 显示文摘 | Sevella B Bertalan G | 2000 | Bioprocess Engineering2000，，23： | 1 |
| 14 | Progress in interface modifications: from compatibihzation to adaptive and smart interpha- ses 显示文摘 | KESZEI S MATKS S BERTALAN G | 2005 | European Polymer Journal2005，41，4： | 1 |
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