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| 1 | Rodent models of fatty liver diseases显示文摘Fatty liver diseases including alcoholic liver disease(ALD)and non-alcoholic fatty liver disease(NAFLD)are leading causes of chronic liver diseases worldwide.ALD and NAFLD encompass a broad spectrum of liver disorders ranging from simple steatosis to steatohepatitis,fibrosis,cirrhosis and superimposed hepatocellular carcinoma.Despite considerable advances in our understanding of the pathogenesis of fatty liver diseases over the past 40 years,effective diagnostic,prognostic,and therapeutic tools are still lacking.The use of animal models is crucial to investigate the cellular and molecular mechanisms underlying the development and progression of fatty liver diseases and develop novel therapeutic strategies.Although no animal model to date can faithfully replicate all the clinical and histological features of ALD or NAFLD,existing models can mimic specific aspects of human diseases.This review provides an overview of the most commonly used and recently developed rodent models of ALD and NAFLD and discusses their major strengths and shortcomings. | Adeline Bertola | 2018 | Liver Research2018，2，1： | 4 |
| 2 | A model of target changes and the term structure of interest rates 显示文摘 | Balduzzi P Bertola G Foresi S | 1997 | Journal of Monetary Economics1997，39，2： | 1 |
| 3 | Effect of freezing conditions on functional properties of low moisture Mozzarella cheese 显示文摘 | Bertola N C Califano A N Bevilacqua A E | 1996 | J Dairy Sci1996，79，2： | 1 |
| 4 | Heat treatment effect on texture changes and thermal denaturation of proteins in beef muscle显示文摘 | BERTOLA N C BEVILACQUA A E ZARITZKY N E | 1994 | Journal of Food Processing and Preservation1994，18，1： | 1 |
| 5 | Effect of freezing conditions on functional properties of low moisture Mozzarella cheese显示文摘 | BERTOLA N C CALIFANO A N BEVILACQUA A E | 1996 | J Dairy Sci1996，79，2： | 1 |
| 6 | The far-ultraviolet spectra of early-type galaxies显示文摘 | BURSTEIN D BERTOLA F BUSON L M et ai | 1988 | Astrophysics Journal1988，328，： | 1 |
| 7 | The application of different techniques to determine activated sludge kinetic parameters in a food industrial wastewater显示文摘 | Contreras E Bertola N Zaritzky N | 2001 | Water S A2001，27，2： | 1 |
| 8 | Effect of freezing conditions on functional properties of low moisture Mozzarella cheese显示文摘 | BERTOLA N C CALIFANO A N BEVILACQUA A E | 1996 | J Dairy Sci1996，79，2： | 1 |
| 9 | Analytical Solution for the Hagen-Poiseuille Flow of a Hard Sphere Gas With NonlinearShear Viscosity显示文摘 | Bertola V Cafaro E | 2007 | J Stat Mech2007，06，06： | 1 |
| 10 | Edible coatings from cellulose derivatives to reduce oil uptake in fried products 显示文摘 | Garcia M A Ferrero C Bertola N | 2002 | Innovative Food Science and Emerging Technologies2002，3，4： | 1 |
| 11 | Design as a knowledge agent: How design as a knowledge process is embedded into organizations to foster innovation显示文摘 | BERTOLA P TEIXEIRA J C | 2003 | Design Studies2003，24，2： | 1 |
| 12 | Elevated expression of osteopontin may be related to adipose tissue macrophage accumulation and liver steatosis in morbid obesity显示文摘 | Bertola A Deveaux V Bonnafous S | 2009 | Diabetes2009，58，1： | 1 |
| 13 | Lowdose thalidomide plus Dexamethasone is an effective salvage therapy for advanced myeloma显示文摘 | PALUMBO A GIACCONE L BERTOLA A | 2001 | Hematologica2001，86，： | 1 |
| 14 | Oral melphalan, prednisone, and thalidomide for newly diagnosed patients with myeloma显示文摘 | PALUMBO A BERTOLA A MUSTO P | 2005 | Cancer2005，104，7： | 1 |
| 15 | Hepatocyte growth factor induces glucose uptake in 3T3-L1 adipocytes through A Gab1/phosphatidylinositol 3-kinase/Glut4 pathway显示文摘 | Bertola A Bonnafous S Cormont M | 2007 | J Biol Chem2007，282，10： | 1 |
| 16 | Firing Costs and Labour Demand: How Bad is Euro- sclerosis? 显示文摘 | Bentolila Samuel Bertola Giuseppe | 1990 | Review of Economic Studies1990，57，191： | 1 |
| 17 | Effect of freezing conditions on functional properties of low moisture Mozzarella cheese显示文摘 | N C Bertola A N Califano A E Bevilacqua | 1996 | J Dairy Sci1996，79，2： | 1 |
| 18 | Low dose thalidomide plus dexamethasone is an effective salvage therapy for advanced myeloma显示文摘 | Palumbo A Giaccone L Bertola A | 2001 | Haematologica2001，86，4： | 1 |
| 19 | Irreversibility and aggregate investment显示文摘 | Bertola G Caballero R | 1994 | Review of Economic Studies1994，61，： | 1 |
| 20 | A prospective randomized trial of oral melphalan,prednisone,thalidomide (MPT) vs oral melphalan,prednisone(MP):an interim analysis显示文摘 | Palumbo A Bertola A Musto P | 2004 | Blood2004，104，： | 1 |
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