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| 1 | Impact of contrast-enhanced ultrasound in patients with renal function impairment显示文摘AIM To investigate the role of contrast enhanced ultrasound(CEUS) in evaluating patients with renal function impairment(RFI) showing:(1) acute renal failure(ARF) of suspicious vascular origin; or(2) suspicious renal lesions.METHODS We retrospectively evaluated patients addressed to CEUS over an eight years period to rule-out vascular causes of ARF(first group of 50 subjects) or assess previously found suspicious renal lesions(second group of 41 subjects with acute or chronic RFI). After preliminary grey-scale and color Doppler investigation, each kidney was investigated individually with CEUS, using 1.2-2.4 m L of a sulfur hexafluoride-filled microbubble contrast agent. Image analysis was performed in consensus by two readers who reviewed digital clips of CEUS. We calculated the detection rate of vascular abnormalities in the first group and performed descriptive statistics of imaging findings for the second group.RESULTS In the first group, CEUS detected renal infarction orcortical ischemia in 18/50 patients(36%; 95%CI: 23.3-50.9) and 1/50 patients(2%; 95%CI: 0.1-12), respectively. The detection rate of infarction was significantly higher(P = 0.0002; Mc Nemar test) compared to color Doppler ultrasonography(10%). No vascular causes of ARF were identified in the remaining 31/50 patients(62%). In the second group, CEUS detected 41 lesions on 39 patients, allowing differentiation between solid lesions(21/41; 51.2%) vs complex cysts(20/41; 48.8%), and properly addressing 15/39 patients to intervention when feasible based on clinical conditions(surgery and cryoablation in 13 and 2 cases, respectively). Cysts were categorized Bosniak Ⅱ, ⅡF, Ⅲ and Ⅳ in 8, 5, 4 and 3 cases, respectively. In the remaining two patients, CEUS found 1 pseudolesion and 1 subcapsular hematoma.CONCLUSION CEUS showed high detection rate of renal perfusion abnormalities in patients with ARF, influencing the management of patients with acute or chronic RFI and renal masses throughout their proper characterization. | Rossano Girometti Tiziano Stocca Elena Serena Antonio Granata Michele Bertolotto | 2017 | World Journal of Radiology2017，9，1： | 3 |
| 2 | The EFSUMB Guidelines and Recommendations on the Clinical Practice of Contrast Enhanced Ultrasound (CEUS): Update 2011 on non-hepatic applications显示文摘 | F. Piscaglia C. Nols?e C. Dietrich D. Cosgrove O. Gilja M. Bachmann Nielsen T. Albrecht L. Barozzi M. Bertolotto O. Catalano M. Claudon D. Clevert J. Correas M. D'Onofrio F. Drudi J. Eyding M. Giovannini M. Hocke A. Ignee E. Jung A. Klauser N. Lassau E. L | 2012 | Ultraschall in Med2012，，01： | 2 |
| 3 | Statin Treatment Is Associated with Reduction in Serum Levels of Receptor Activator of NF- κ B Ligand and Neutrophil Activation in Patients with Severe Carotid Stenosis显示文摘 | Sébastien Lenglet Alessandra Quercioli Mathias Fabre Katia Galan Graziano Pelli Alessio Nencioni Inga Bauer Aldo Pende Magaly Python Maria Bertolotto Giovanni Spinella Bianca Pane Domenico Palombo Franco Dallegri Fran?ois Mach Nicolas Vuilleumier Fabrizio | 2014 | Mediators of Inflammation2014，，： | 2 |
| 4 | GLP-1 promotes islet cells growth and inhibits cell apoptosis in Zucker diabetic rats 显示文摘 | Farilla L hui H Bertolotto C | 2002 | Endocrinology2002，143，11： | 1 |
| 5 | Narrow band imaging for detecting residual/recurrent cancerous tissue during second transurethral resection of newly diagnosed non-muscle-invasive high-grade bladder cancer显示文摘 | Naselli A Introini C Bertolotto F | 2010 | BJU Int2010，105，2： | 1 |
| 6 | Physical activity and dietary habits during pregnancy: effects on glucose tolerance 显示文摘 | Bertolotto A Volpe L Calianno A | 2010 | J Matern Fetal Neonatal Med2010，23，11： | 1 |
| 7 | Detection of liver metastases with pulse inversion harmonic imaging: Preliminary results显示文摘 | L. Dalla Palma M. Bertolotto E. Quaia M. Locatelli | 1999 | European Radiology1999，，3： | 1 |
| 8 | Single-Phase Mixing Studies by Means of A Directly CoupledCfd/System-Code Tool显示文摘 | Bertolotto D Manera A Frey S | 2009 | Annals of Nuclear Energy2009，36，3： | 1 |
| 9 | Progressive transmission of vector map data over the world wide web 显示文摘 | BERTOLOTTO M EGENHOFER M J | 2001 | Geoinformatica2001，5，4： | 1 |
| 10 | Insulin and glucose regulate the expression of the DNA repair enzyme XPD 显示文摘 | Merkel P Khoury N Bertolotto C | 2003 | Mol Cell Endocrinol2003，201，12： | 1 |
| 11 | Current role of color Doppler ultrasound in acute renal failure显示文摘 | Bertolotto M Quaia E Rimondini A | 2001 | Radiol Med (Torino)2001，102，56： | 1 |
| 12 | Spatial ()nline Analytical Processing of Geographic Data through the Google Earth Interface显示文摘 | Martin() S D Bimonte S Bertolotto M | 2011 | Geoeomputation Sustainability and Envi- ronmental Planning2011，348，： | 1 |
| 13 | Characterization of fi)cal liver lesions with contrast - specific US modes and a sulfur hex',fflu- oride- filled microbubble contrast agent: Diagnostic performance and confidence显示文摘 | Quaia E Calliada F Bertolotto M | 2004 | Radiology2004，232，： | 1 |
| 14 | Characterization of focal liver lesions with contrast-speciflc US modes and a sulfur hexafluoride-filled microbubble contrast agent: diagnostic performance and confidence 显示文摘 | Quaia E Calliada F Bertolotto M | 2004 | Radiology2004，232，2： | 1 |
| 15 | SOX9 is a key player in ultraviolet B-induced melanocyte differentiation and pigmenta- tion显示文摘 | Passeron T Valencia JC Bertolotto C | 2007 | Proc Natl Acad Sei2007，104，13： | 1 |
| 16 | Oxidative stress mediates apoptotic changes induced by hyperglycemia in human tubular kidney cells显示文摘 | Verzola D Bertolotto MB Villaggio B | 2004 | J Am Soc2004，15，1： | 1 |
| 17 | Glucagon -like -peptide - 1 promotes islet cell growth and inhibits apoptosis in Zucker diabetic rats 显示文摘 | Farilla L Hui H Bertolotto C | 2002 | Endocrinology2002，143，： | 1 |
| 18 | Human mesenchymal stem cell inhibit neutrophil apoptosis:a model for neutrophil preservation in the bone marrow niche显示文摘 | Raffaghello L Bianchi G Bertolotto M | 2008 | Stem Cells2008，26，1： | 1 |
| 19 | Human mesenchymal stem cells inhibit neutrophil apoptosis:A model for neutrophilpreservation in the bone marrow niche显示文摘 | Raffaghello L Bianchi G Bertolotto M | 2008 | Stem Cells2008，26，1： | 1 |
| 20 | Cyclic AMP promotes a peripheral distribution of melanosomes and stimulates melanophilin/Slac2-a and actin association显示文摘 | Passeron T Bahadoran P Bertolotto C | 2004 | The FASEB Journa2004，18，9： | 1 |
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