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| 1 | 食管腺癌淋巴结转移与肿瘤侵及食管壁深度的关系显示文摘目的对腺癌侵及食管壁深度与淋巴结转移的关系以及淋巴结转移对预后的影响进行分析研究。方法澳大利亚弗林德斯大学医学中心自1985年~2003年,手术治疗食管腺癌121例。其中男101例,女20例。年龄36~80岁,平均62岁。本组手术切除率为96.7%(117/121例)。手术清扫淋巴结的数目每例为2~30个,平均8个。无淋巴结转移59例(48.8%)、有淋巴结转移62例(51.2%)。本组病例全部得到随访。结果当肿瘤位于黏膜层或黏膜下层(T1)时,淋巴结转移的发生率为22.2%(10/45例)、平均淋巴结转移的个数为0.3个、>4个淋巴结转移的比例为0(0/45例);当肿瘤侵及食管周围组织(T4)时,淋巴结转移的发生率为85.7%(6/7例)、平均淋巴结转移的个数为5.1个、>4个淋巴结转移的比例为71.4%(5/7例),P<0.05。无淋巴结转移组的5年生存率为52.9%、1~4个淋巴结转移组的5年生存率为11.5%、>4个淋巴结转移组的5年生存率为0,P<0.01。结论肿瘤对食管壁侵及深度和淋巴结转移的发生率及淋巴结转移的数量之间存在正相关性。随着肿瘤对食管壁侵及深度的增加,淋巴结转移的发生率、平均淋巴结转移的数量和>4个淋巴结转移的比例均增加。有无淋巴结转移和淋巴结转移的数量是影响远期生存率的一个重要因素。 | 张逊 David I. Watson Justin R. Bessell | 2006 | 中华胸心血管外科杂志2006，22，5： | 5 |
| 2 | Preoperative radiotherapy versus selective postoperative chemoradiotherapy in patients with rectal cancer (MRC CR07 and NCIC-CTG C016): a multicentre, randomised trial显示文摘 | David Sebag-Montefiore Richard J Stephens Robert Steele John Monson Robert Grieve Subhash Khanna Phil Quirke Jean Couture Catherine de Metz Arthur Sun Myint Eric Bessell Gareth Griffiths Lindsay C Thompson Mahesh Parmar | 2009 | The Lancet2009，，9666： | 5 |
| 3 | Outcomes of Roux-en-Y gastric bypass and laparoscopic adjustable gastric banding显示文摘AIM:To evaluate weight loss and surgical outcomes of Roux-en-Y gastric bypass(RYGB)and laparoscopic adjustable gastric band(LAGB).METHODS:Data relating to changes in body mass index(BMI)and procedural complications after RYGB(1995-2009;n=609;116M:493F;42.4±0.4 years)or LAGB(2004-2009;n=686;131M:555F;37.2±0.4years)were extracted from prospective databases.RESULTS:Pre-operative BMI was higher in RYGB than LAGB patients(46.8±7.1 kg/m2vs 40.4±4.2 kg/m2,P<001);more patients with BMI<35 kg/m2underwent LAGB than RYGB(17.1%vs 4.1%,P<0.0001).BMI decrease was greater after RYGB.There were direct relationships between weight loss and pre-operative BMI(P<0.001).Although there was no difference in weight loss between genders during the first 3-year post-surgery,male LAGB patients had greater BMI reduction than females(-8.2±4.3 kg/m2vs-3.9±1.9kg/m2,P=0.02).Peri-operative complications occurred more frequently following RYGB than LAGB(8.0%vs0.5%,P<0.001);majority related to wound infection.LAGB had more long-term complications requiring corrective procedures than RYGB(8.9%vs 2.1%,P<0.001).Conversion to RYGB resulted in greater BMI reduction(-9.5±3.8 kg/m2)compared to removal and replacement of the band(-6.0±3.0 kg/m2).Twelve months post-surgery,fasting glucose,total cholesterol and low density lipoprotein levels were significantly lower with the magnitude of reduction greater in RYGB patients.CONCLUSION:RYGB produces substantially greater weight loss than LAGB.Whilst peri-operative complications are greater after RYGB,long-term complication rate is higher following LAGB. | Nam Q Nguyen Philip Game Justin Bessell Tamara L Debreceni Melissa Neo Carly M Burgstad Pennie Taylor Gary A Wittert | 2013 | World Journal of Gastroenterology2013，19，36： | 3 |
| 4 | Preoperative radiotherapy versus selective postoperative chemoradiotherapy in patients with rectal cancer (MRC CR07 and NCIC-CTG C016): a multicentre, randomised trial显示文摘 | David Sebag-Montefiore Richard J Stephens Robert Steele John Monson Robert Grieve Subhash Khanna Phil Quirke Jean Couture Catherine de Metz Arthur Sun Myint Eric Bessell Gareth Griffiths Lindsay C Thompson Mahesh Parmar | 2009 | The Lancet2009，，9666： | 3 |
| 5 | Preoperative radiotherapy versus selective postoperative chemoradiotherapy in patients with rectal cancer (MRC CR07 and NCIC-CTG C016): a multicentre, randomised trial显示文摘 | David Sebag-Montefiore Richard J Stephens Robert Steele John Monson Robert Grieve Subhash Khanna Phil Quirke Jean Couture Catherine de Metz Arthur Sun Myint Eric Bessell Gareth Griffiths Lindsay C Thompson Mahesh Parmar | 2009 | The Lancet . 2009 (9666)2009，，9666： | 3 |
| 6 | A step-up proach or open necrosectomy for necrotizing pan- creatitis显示文摘 | Van Santvoort HC Bessel ink MG Bakker OJ | 2010 | N Engl J Med2010，362，16： | 1 |
| 7 | A randomized controlled trial assessing he benefit of humidified insufflation gas during laparoscopic surgery显示文摘 | Moutori WG Bessell JR Millard SH | 1998 | Surg Endosc1998，13，： | 1 |
| 8 | Pain after laparosoecopy显示文摘 | Mouton WG Bessell JR Otten KT etal | 1999 | Surg Endosc1999，13，5： | 1 |
| 9 | Importance of radiotherapy in the outcome of patients with primary CNS lymphoma: an analysis of the CHOD/BVAM regimen fol- lowed by two different radiotherapy treatments 显示文摘 | Bessell EM Lopez-Guillermo A Villa S | 2002 | J Clin Oncol2002，20，： | 1 |
| 10 | A theory of elastic, plastic, and creep deformations of an initially isotropic material showing anisotropic strain -hardening, creep re- covery, and secondary creep 显示文摘 | Besseling J F | 1958 | Journal of Applied Mechanics1958，，： | 1 |
| 11 | Association Between Familial Hypereholesterolemia and Prevalence of Type 2 Diabetes Mellitus 显示文摘 | Besseling J Kastelein JJ Defesche JC | 2015 | JAMA2015，313，10： | 1 |
| 12 | Pain after laparoscopy 显示文摘 | Mouton WG Bessell JR Otten KT | 1999 | SurgEndosc1999，13，5： | 1 |
| 13 | Detection and tracking using particle-filter-based wireless sensor networks显示文摘 | AHMED N RUTYEN M BESSELL T et el | 2010 | IEEE Trans on Mobile Computing2010，9，9： | 1 |
| 14 | A randomized controlled trial assessing he benefit of humidified insufflation gas during laparoscopic surgery显示文摘 | Mouton WG Bessell JR Millard SH | 1998 | Surg Endosc1998，13，： | 1 |
| 15 | The law of one price: developed and developing country market integration显示文摘 | JIAN Y D BESSELER A LEATHAM D J | 2000 | Journal of Agricultural and Applied Economics2000，32，3： | 1 |
| 16 | Measuring Prevalence: Prevalence of South Australia' s Online Health Seekers显示文摘 | Bessell T L Silagy C A Anderson J N | 2002 | Australian and New Zealand Journal of Public Health2002，26，2： | 1 |
| 17 | The use of deoxyfluoro-D-glucopyranoses and related com-pounds in a study of yeast hexokinase specificity显示文摘 | Bessell EM Foster AB Westwood JH | 1972 | Biochem J1972，128，2： | 1 |
| 18 | Support effects in cobalt-based fischer-tropsch catalysis 显示文摘 | BESSELL S | 1993 | Applied Catalysis A1993，96，2： | 1 |
| 19 | Statistical modeling of holding level susceptibility to infection during the 2001 foot and mouth disease epidemic in Great Britain 显示文摘 | Bessell PR Shaw DJ Savill NJ | 2010 | Interna- tional Journal of Infectious Diseases2010，14，3： | 1 |
| 20 | The Law of OnePrice:Developed and Developing Country Market Integration 显示文摘 | Jian Y Besseler D A Leatham D J | 2000 | Journal of Agricultural and Apphed Economics2000，，3： | 1 |
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