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| 1 | Comparison of the Exeter Trauma Stem and the Thompson hemiarthroplasty for intraeapsular hip fractures显示文摘 | Bidwai AS Willett KM | 2012 | Hip Int2012，22，6： | 1 |
| 2 | Blood-pressure and pulse-rate response to endotmcheal extubation with and without prior injection of lidocine显示文摘 | Bidwai VA Rogers CR | 1979 | Anesthesiology1979，51，2： | 1 |
| 3 | One step forward, many steps back: dismemberment of India's National Drug Policy显示文摘 | BIDWAI P | 1995 | Dev Dial1995，1，： | 1 |
| 4 | Balloon control of the saphenofemoral junction during foam sclerotherapy:proposed innovation显示文摘 | Bidwai A Beresford T Dialynas M | | 0，，： | 1 |
| 5 | Blood Pressure and pulserate response to endotrucheal extubation with and without prior injection显示文摘 | Bidwai AV Bidwai VA Rogers CR | 1979 | Anesthesiology1979，51，： | 1 |
| 6 | Blood pressure and pulse rate responses to extubation with and without prior topical tracheal anaesthesia显示文摘 | Bidwai AV Stanley TH | 1978 | Can Anaesth Soc J1978，5，5： | 1 |
| 7 | The role of the length and sequence of the linker domain of cytochrome b5 in stimulating cytochrome P450 2B4 catalysis显示文摘 | Clarke T A Im S C Bidwai A | | 0，，35： | 1 |
| 8 | Blood pressure and pulse-rate responses to endotracheal extubation with and without prior injection of lidocaine显示文摘 | Bidwai AR Bidwai VA Rodgers CR | 1979 | Anesthesiology1979，51，： | 1 |
| 9 | pH dependence of cyanide binding to the ferric heme domain of the direct oxygen sensor from eseherichia eoli and the effect of alkaline denaturation显示文摘 | BIDWAI A K OK E Y ERMAN J E | 2008 | Biochemistry2008，47，10： | 1 |
| 10 | Blood pressure and pulse rate responses to endotracheal extubation with and without prior injection of lidocaine 显示文摘 | Bidwai AV Bidwai VA Rogers CR | 1979 | Anesthesiology1979，51，2： | 1 |
| 11 | Interaction of casein kinase Ⅱ with ribosomal protein L22 of Drosophila melanogaster 显示文摘 | Zhao W Bidwai AP Glover CV | 2002 | Biochem Biophys Res Commun2002，298，1： | 1 |
| 12 | Blood pressure and pulse rate response to endotracheal extrbation with and without prior injection 显示文摘 | Bidwai AV Bidwai VA Rogers CR | 1979 | Anesthesiologay1979，5，1： | 1 |
| 13 | Interaction of casein kinase Ⅱ with ribosomal protein L22 of Drosophila melanogaster 显示文摘 | Zhao W Bidwai AP Glover CV | 2002 | Biochem Biophys Res Commun2002，298，1： | 1 |
| 14 | Nationalism Gone Berserk显示文摘 | Praful Bidwai | 2002 | Frontline2002，19，3： | 1 |
| 15 | Cardiovascular dynamics after large doses of fentanyl and fentanyl plus N20 in the dog 显示文摘 | Liu WS Bidwai AV Stanley TH | 1976 | Anesth Analg1976，55，： | 1 |
| 16 | Doom, a product of the Drosophila Mod (mdg4) gene, induces apoptosis and binds to baculovirus inhibitor-of-apoptosis proteins 显示文摘 | Harvey A J Bidwai A P Miller L K | 1997 | Mol Cell Biol1997，17，： | 1 |
| 17 | Blood pressure and pulse rate responses to endo-tracheal extrubation with and without prior injection of lidocaine显示文摘 | Bidwai AV Bidwai VA Rogars CR | 1979 | Anesthesiology1979，51，： | 1 |
| 18 | Doom, a Product of the Drosophila mod(mdg4) Gene,Induces Apoptosis and Binds to Baculovirus Inhibitor-of-Apoptosis Proteins显示文摘 | Harvey AJ Bidwai AP Miller LK | 1997 | Mol Cell Biol1997，17，5： | 1 |
| 19 | Molecular docking of amphetamine,cathine and cathinone with dihydrofolate reductase:a computational analysis of inhibition of dihydrofolate reductase by khat alkaloids显示文摘Interaction of amphetamine,cathine and cathinone with the enzyme dihydrofolate reductase was studied by molecular docking using AutoDock 4.2 as the docking software application.AutoDock 4.2 software serves as a valid and acceptable docking application to study the interactions of small compounds with proteins.Interactions of amphetamine,cathine and cathinone with dihydrofolate reductase were compared to those of methotrexate,a known inhibitor of the enzyme.The calculated free energy of binding(ΔG binding)shows that the three ligands(ΔG=-6.87 to-7.21 kcal/mol;Ki=9.15 to 5.18μM)bind with affinity slightly lower than methotrexate(ΔG=-8.78 kcal/mol;Ki=363 nM).Binding interactions of the three ligands with active site residues of the enzyme are also predicted.All the ligands appear to bind in a similar conformation making extensive VDW contacts in the active site of the enzyme.Hydrogen bonding and pi-pi interaction with key active site residues is also observed.Thus,a probable inhibition of dihydrofolate reductase by khat alkaloids can be explained on the basis of this in silico binding and khat alkaloids can be considered as potential lead compounds in the development of new inhibitors of dihydrofolate reductase which is a potential target of anti-cancer drugs.The results of these studies can serve as a starting point for further computational and experimental studies. | Siddig Ibrahim Abdelwahab Abdullah Farasani Ahmed Jerah Manal Mohamed Elhassan Taha Anil Bidwai | 2022 | Toxicology Communications2022，4，2： | 0 |
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