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| 1 | Prognostic value of pre-treatment F-18-FDG PET-CT in patients with hepatocellular carcinoma undergoing radioembolization显示文摘AIM To evaluate the value of pre-treatment 18F-FDG PET/CT in patients with HCC following liver radioembolization.METHODS We identified 34 patients with HCC who underwent an FDG PET/CT scan prior to hepatic radioembolization at our institution between 2009 and 2013. Patients wereseen in clinic one month after radioembolization and then at 2-3 mo intervals. We assessed the influence of FDG tumor uptake on outcomes including local liver control(LLC), distant liver control(DLC), time to distant metastases(DM), progression free survival(PFS) and overall survival(OS).RESULTS The majority of patients were males(n = 25, 74%), and had Child Pugh Class A(n = 31, 91%), with a median age of 68 years(46-84 years). FDG-avid disease was found in 19(56%) patients with SUVmax ranging from 3 to 20. Female patients were more likely to have an FDG-avid HCC(P = 0.02). Median follow up of patients following radioembolization was 12 months(1.2-62.8 mo). FDG-avid disease was associated with a decreased 1 year LLC, DLC, DM and PFS(P < 0.05). Using multivariate analysis, FDG avidity predicted for LLC, DLC, and PFS(all P < 0.05).CONCLUSION In this retrospective study, pre-treatment HCC FDGavidity was found to be associated with worse LLC, DLC, and PFS following radioembolization. Larger studies are needed to validate our initial findings to assess the role of F-18-FDG PET/CT scans as biomarker for patients with HCC following radioembolization. | Yazan Abuodeh Arash O Naghavi Kamran A Ahmed Puja S Venkat Youngchul Kim Bela Kis Junsung Choi Benjamin Biebel Jennifer Sweeney Daniel A Anaya Richard Kim Mokenge Malafa Jessica M Frakes Sarah E Hoffe Ghassan El-Haddad | 2016 | World Journal of Gastroenterology2016，22，47： | 3 |
| 2 | Hearing loss in athyroid pax8 knockout mice and effects of thyroxine substitution显示文摘 | Christ S Biebel U W Hoidis S | 2004 | Audiol & Neurooto|2004，9，2： | 1 |
| 3 | Development of controlled drug release systems based on polymer-cysteine conjugates显示文摘 | Bernkop-Schnurch A Scholler S Biebel RG | 2000 | J Controlled Release2000，66，1： | 1 |
| 4 | Why do mechanical seal fail显示文摘 | Peter Biebel | 1990 | Plant services magazine1990，92，： | 1 |
| 5 | Development of controlled drug release systems based on thiolated polymers显示文摘 | Bernkop-Schnurch A Scholler S Biebel RG | 2000 | J Controlled Release2000，66，1： | 1 |
| 6 | Women's perspec- tives on postpartum depression screening in pediatric set- tings: a preliminary study 显示文摘 | Byatt N Biebel K Friedman L | 2013 | Arch Women 's Ment Health2013，16，5： | 1 |
| 7 | Review of Particle Physics显示文摘 | C. Amsler M. Doser M. Antonelli D.M. Asner K.S. Babu H. Baer H.R. Band R.M. Barnett E. Bergren J. Beringer G. Bernardi W. Bertl H. Bichsel O. Biebel P. Bloch E. Blucher S. Blusk R.N. Cahn M. Carena C. Caso A. Ceccucci D. Chakraborty M.-C. Chen R.S. Chivuk | 2008 | Physics Letters B2008，，1： | 1 |
| 8 | The effects of bacteria overgrowth and hemorrhagic Shock on mocosal immunity显示文摘 | Gordon DM biebel LN Liberati DM | 1998 | Am Surg1998，64，8： | 1 |
| 9 | Development of controlled drug release systems based on thiolated polymers 显示文摘 | Bernkop-Schnurch A Biebel RG Scholler S | 2000 | J Controlled Release2000，166，1： | 1 |
| 10 | Development of controlled drug release systems based on thiolated polymers 显示文摘 | Bernkop-Schnureh A Scholler S Biebel RG | 2000 | J Controlled Release2000，66，1： | 1 |
| 11 | Why do mechanical seals fail显示文摘 | | 1990 | Plant Services Magazine1990，，： | 1 |
| 12 | Plasmatic resiitance and rate of respiration and photosynthesis of Zostera marina at different salinities and temperatures显示文摘 | BIEBEL R MCROY C P | 1971 | Mar Biol1971，8，： | 1 |
| 13 | FRAGMENTATION FUNCTIONS IN e+e-, ep AND pp COLLISIONS显示文摘 | O. Biebel D. de Florian D. Milstead A. Vogt | 2016 | Chinese Physics C2016，40，10： | 0 |
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