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| 1 | Impact of postoperative omega-3 fatty acid-supplemented parenteral nutrition on clinical outcomes and immunomodulations in colorectal cancer patients显示文摘AIM: To investigate the effect of omega-3 fatty acid parenteral supplementation postoperatively on clinical outcomes and immunomodulation in colorectal cancer patients. METHODS: Forty-two patients undergoing radical colorectal cancer resection with an indication for total parenteral nutrition postoperatively were enrolled in this prospective, double-blind, randomized, controlled study. Patients received total parenteral nutrition supplemented with either soybean oil (LCT; Intralipid, Fresenius-Kabi, SO group, n = 21) or a combination of omega-3 fish oil and soybean oil (LCT:fish oil = 5:1, fish oil; Omegaven, Fresenius-Kabi, FO group, n = 21), up to a total of 1.2 g lipid/kg per day for 7 d postoperatively. A same volume calorie and nitrogen was administrated. Routine blood test, biochemistry, systemic levels of IL-6 and TNF-α, percentage of CD3+, CD4+, and CD8+ lymphocytes were evaluated preoperatively and on postoperative d 1 and 8. Patient outcome was evaluated considering mortality during the hospital stay, length of postoperative hospital stay, and occurrence of infectious complications. RESULTS: Both lipid regimens were well tolerated. No differences between the two groups were noticed in demographics, baseline blood test, biochemistry, serum levels of IL-6 and TNF-α, percentage of CD4+, CD8+ lymphocytes, and ratios of CD4+/CD8+. Compared with those on postoperative d 1, serum IL-6 levels onpostoperative d 8 were significantly depressed in the FO group than in the reference group (-44.43 ± 30.53 vs -8.39 ± 69.08, P = 0.039). Simultaneously, the ratios of CD4+/CD8+ were significantly increased in the FO group (0.92 ± 0.62 vs 0.25 ± 1.22, P = 0.035). In addition, depression of serum TNF-α levels (-0.82 ± 2.71 vs 0.27 ± 1.67, P = 0.125) and elevation of CD3+ and CD4+ lymphocyte percentage (12.85 ± 11.61 vs 3.84 ± 19.62, P = 0.081, 17.80 ± 10.86 vs 9.66 ± 17.55, P = 0.084, respectively) were higher in the FO group than in the reference group. Patients in the FO group trended to need a shorter postoperative hospital stay (17.45 ± 4.80 d vs 19.62 ± 5.59 d, P = 0.19). No statistically significant difference was found when stratified to mortality and occurrence of infectious complications. CONCLUSION: Postoperative supplementation of omega-3 fatty acids may have a favorable effect on the outcomes in colorectal cancer patients undergoing radical resection by lowering the magnitude of inflammatory responses and modulating the immune response. | Bin Liang, Shan Wang, Ying-Jiang Ye, Xiao-Dong Yang, You-Li Wang, Jun Qu, Qi-Wei Xie, Mu-Jun Yin, Division of Surgical Oncology and Division of Gastroenterological Surgery, Peking University People’s Hospital, Beijing 100044, China Author contributions: Liang B and Wang S contributed equally to this work Liang B and Wang S designed the research Liang B, Ye YJ, Yang XD, Wang YL, Qu J, Xie QW, Yin MJ performed the research and collected the data Wang S and Ye YJ supervised the research Liang B and Ye YJ analyzed the data Liang B wrote the paper and revised the manuscript. | 2008 | World Journal of Gastroenterology2008，14，15： | 31 |
| 2 | Weighted Multi-sensor Data Level Fusion Method of Vibration Signal Based on Correlation Function显示文摘As the differences of sensor's precision and some random factors are difficult to control,the actual measurement signals are far from the target signals that affect the reliability and precision of rotating machinery fault diagnosis.The traditional signal processing methods,such as classical inference and weighted averaging algorithm usually lack dynamic adaptability that is easy for trends to cause the faults to be misjudged or left out.To enhance the measuring veracity and precision of vibration signal in rotary machine multi-sensor vibration signal fault diagnosis,a novel data level fusion approach is presented on the basis of correlation function analysis to fast determine the weighted value of multi-sensor vibration signals.The approach doesn't require knowing the prior information about sensors,and the weighted value of sensors can be confirmed depending on the correlation measure of real-time data tested in the data level fusion process.It gives greater weighted value to the greater correlation measure of sensor signals,and vice versa.The approach can effectively suppress large errors and even can still fuse data in the case of sensor failures because it takes full advantage of sensor's own-information to determine the weighted value.Moreover,it has good performance of anti-jamming due to the correlation measures between noise and effective signals are usually small.Through the simulation of typical signal collected from multi-sensors,the comparative analysis of dynamic adaptability and fault tolerance between the proposed approach and traditional weighted averaging approach is taken.Finally,the rotor dynamics and integrated fault simulator is taken as an example to verify the feasibility and advantages of the proposed approach,it is shown that the multi-sensor data level fusion based on correlation function weighted approach is better than the traditional weighted average approach with respect to fusion precision and dynamic adaptability.Meantime,the approach is adaptable and easy to use,can be applied to other areas of vibration measurement. | BIN Guangfu JIANG Zhinong LI Xuejun DHILLON B S | 2011 | Chinese Journal of Mechanical Engineering2011，24，5： | 7 |
| 3 | The magnetic properties of Serbian loess and its environmental significance显示文摘This paper reports a loess-paleosol sequence located in the Danube River basin,Serbia,which formed at least since the latest part of the early Pleistocene,and before the paleomagnetic B/M boundary.Various magnetic parameters of the Serbian V-L1-V-S4 loess-paleosol sequence have been measured and analyzed in the Titel Loess Plateau.These parameters show a very similar magnetic behavior compared with that of the Chinese loess.There is a general positive relationship between magnetic susceptibility() and pedogenesis.The main contributors to are the magnetic grains of SP(superparamagnetic) and SD(single domain) magnetic domains,while MD(multi domain) contributes only a small percentage.The difference in between loess and paleosol mainly is caused by pedogenesis.The very fine magnetic minerals increase gradually with increasing soil development(from loess to soil),and they lead to higher.The thermomagnetic curves show thatmagnetic minerals in the loess layers are magnetite and maghemite,both providing a major contribution to.In contrast the paleosol layers mainly are composed of magnetite,with almost no or a very small amount of maghemite,as implied by a reversible thermomagnetic behavior.This indicates that pedogenic conditions during V-S3 and V-S4 strong soil development have resulted in maghemite that is no longer stable,and has been resolved or converted to other stable phase minerals.This likely indicates that soil moisture during V-S3 and V-S4 development exceeded a critical condition of maghemite stability. | LIU XiuMing LIU Zhi Lü Bin MARKOVI S B CHEN JiaSheng GUO Hui MA MingMing ZHAO GuoYong FENG Hua | 2013 | Chinese Science Bulletin2013，58，3： | 7 |
| 4 | STAT3 associates with vacuolar H^+-ATPase and regulates cytosolic and lysosomal pH显示文摘 | Bin Liu Johan Palmfeldt Lin Lin Alexandria Colaco Knut K. B, Clemmensen Jinrong Huang Fengping Xu Xin Liu Kenji Maeda Yonglun Luo Marja Jaattela | 2018 | Cell Research2018，28，10： | 5 |
| 5 | Intensive blood pressure reduction in acute cerebral haemorrhage trial (INTERACT): a randomised pilot trial显示文摘 | Craig S Anderson Yining Huang Ji Guang Wang Hisatomi Arima Bruce Neal Bin Peng Emma Heeley Christian Skulina Mark W Parsons Jong Sung Kim Qing Ling Tao Yue Chun Li Jian Dong Jiang Li Wen Tai Jin Li Zhang En Xu Yan Cheng Stephane Heritier Lewis B Morgenste | 2008 | Lancet Neurology2008，，5： | 4 |
| 6 | Effect of Sr on microstructure and aging behavior of Mg-14Li alloys | Bin Jiang a,b,c,Ying Zeng b,Hengmei Yin a,b,Ruihong Li a,b,Fusheng Pan a,b a National Engineering Research Center for Magnesium Alloys,Chongqing University,Chongqing 400030,China b College of Materials Science and Engineering,Chongqing University,Chongqing 400030,China c New Materials Center,Chongqing Academy of Science and Technology,Chongqing 401123,China | 2012 | Progress in Natural Science:Materials International2012，22，2： | 3 |
| 7 | A Perivascular Origin for Mesenchymal Stem Cells in Multiple Human Organs显示文摘 | Mihaela Crisan Solomon Yap Louis Casteilla Chien-Wen Chen Mirko Corselli Tea Soon Park Gabriella Andriolo Bin Sun Bo Zheng Li Zhang Cyrille Norotte Pang-Ning Teng Jeremy Traas Rebecca Schugar Bridget M. Deasy Stephen Badylak Hans-J?rg B?hring Jean-Paul Gi | 2008 | Cell Stem Cell2008，，3： | 3 |
| 8 | Two contrasting Paleozoic magmatic belts in northern Inner Mongolia,China: petrogenesis and tectonic implications 显示文摘 | CHEN Bin Jahn B M Wilde S | 2000 | Tectonophysics2000，328，： | 1 |
| 9 | Two contrasting Paleozoic magmatic belts in northern Inner Mongolia,China:Petrogenesis and tectonic implications显示文摘 | Chen Bin Jahn B M Wilde S | | 0，，： | 1 |
| 10 | Internet-based SCADA display system显示文摘 | QIU Bin GOOI H B | 2002 | IEEE Trans on Power Systems2002，15，1： | 1 |
| 11 | A simple method for the assessment of the cloud cover state in high-latitude regions by a ground-based digital camera显示文摘 | Souza-Echer M P Pereir A E B Bins L S | 2006 | J Atmos Ocean Technol2006，23，3： | 1 |
| 12 | Targeted knock down of Notch1 inhibits invasion of human prostate cancer ceils concomitant with inhibition of matrix metalloproteinase-9 and urokinase plasminogen activator 显示文摘 | Bin Hafeez B Adhami VM Asim M | 2009 | Clin Cancer Res2009，15，2： | 1 |
| 13 | Cancer treatment adherence among low-income women with breast or gynecologic cancer: a randomized con- trolled trial of patient navigation 显示文摘 | Ell K Vourlekis B Bin X | 2009 | Cancer2009，115，19： | 1 |
| 14 | Hydrodynamics and ozone mass transfer in a tall bubble column显示文摘 | Bin A K Duczmal B Machniewski P | 2001 | Chemical Engineering Science2001，56，： | 1 |
| 15 | Novel inhibitory function of miR125bin melanogenesis显示文摘 | Kim K H Bin B H Kim J | 2014 | Pigm Cell Melanoma R2014，27，1： | 1 |
| 16 | Intensity modulated radiation therapy(IMRT) : a new promising teehnology in radiation oncology显示文摘 | Bin ST Shiao YW Brian B | 1999 | The Oneologist1999，4，6： | 1 |
| 17 | The dynamics of online word-of-mouth and product sales-An empirical investigation of the movie industry显示文摘 | Wenjing Duan Bin Gu Andrew B Whinston | 2008 | Journal of Retailing2008，84，2： | 1 |
| 18 | Absorption and migration of bio-based epoxidized soybean oil and its mixtures with tri(2-2ethylhexyl)trimellitate in poly(vinylchloride)显示文摘 | Di M Indu C B Bin S | 2001 | Journal of Applied Polymer Science2001，26，7： | 1 |
| 19 | Do online reviews matter? -an empirical investigation of panel data显示文摘 | Wenjing Duan Bin Gu Andrew B Whinston | 2008 | Decision Support Systems2008，45，4： | 1 |
| 20 | Channel coordination under fairness concerns and nonlinear de- mand 显示文摘 | CALISKAN - DEMIRAG O YOUHUA (FRANK) C B LI JIAN- BIN | 2010 | European Journal of Operational Research2010，，207： | 1 |
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