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2篇 您的检索式：作者名="Binghao Lu"

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		题名	作者	年代	出处	被引量
	1	Estimation of Incident-Induced Congestion on Signalized Arteries Using Traffic Sensor Data显示文摘This paper describes how to derive quantitative information about the effect of traffic incidents on urban traffic flow from the raw measurements detected by sectional loop sensors. The two critical parameters of the travel delay and queue length, which reflect the temporal and spatial properties of incident-induced congestion, cannot be directly determined from commonly used loop sensors. The modified queuing diagram is used here to quantify incident-induced queues and travel delays on signalized arteries using sensor data from the targeted and upstream links. The method is tested using data generated by the VISSIM simulation model, with results indicating its efficiency and accuracy with an average relative travel delay error of 18.67% for all samples which falls to 8.07% for high volume and very high volume conditions.	Lin Hou Zuo Zhang Binghao Lu Runmin Xu Yi Zhang	2012	Tsinghua Science and Technology2012，17，3：	2
	2	Enhancement of T cell infiltration via tumor-targeted Th9 cell delivery improves the efficacy of antitumor immunotherapy of solid tumors显示文摘Insufficient infiltration of T cells severely compromises the antitumor efficacy of adoptive cell therapy(ACT)against solid tumors.Here,we present a facile immune cell surface engineering strategy aiming to substantially enhance the anti-tumor efficacy of Th9-mediated ACT by rapidly identifying tumor-specific binding ligands and improving the infiltration of infused cells into solid tumors.Non-genetic decoration of Th9 cells with tumor-targeting peptide screened from phage display not only allowed precise targeted ACT against highly heterogeneous solid tumors but also substantially enhanced infiltration of CD8+T cells,which led to improved antitumor outcomes.Mechanistically,infusion of Th9 cells modified with tumor-specific binding ligands facilitated the enhanced distribution of tumor-killing cells and remodeled the immunosuppressive microenvironment of solid tumors via IL-9 mediated immunomodulation.Overall,we presented a simple,cost-effective,and cell-friendly strategy to enhance the efficacy of ACT against solid tumors with the potential to complement the current ACT.	Tao Chen Yucheng Xue Shengdong Wang Jinwei Lu Hao Zhou Wenkan Zhang Zhiyi Zhou Binghao Li Yong Li Zenan Wang Changwei Li Yinwang Eloy Hangxiang Sun Yihang Shen Mohamed Diaty Diarra Chang Ge Xupeng Chai Haochen Mou Peng Lin Xiaohua Yu Zhaoming Ye	2023	Bioactive Materials2023，，5：	0

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