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35篇 您的检索式：作者名="Biswal J"

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	题名	作者	年代	出处	被引量
1	Nrf2 is required for normal postnatal bone acquisition in mice显示文摘A large body of literature suggests that bone metabolism is susceptible to the ill effects of reactive species that accumulate in the body and cause cellular dysfunction. One of the body's front lines in defense against such damage is the transcription factor, Nrf2. This transcription factor regulates a plethora of antioxidant and cellular defense pathways to protect cells from such damage. Despite the breadth of knowledge of both the function of Nrf2 and the effects of reactive species in bone metabolism, the direct role of Nrf2 in skeletal biology has yet to be thoroughly examined. Thus, in the current study, we have examined the role of Nrf2 in postnatal bone metabolism in mice. Mice lacking Nrf2(Nrf22/2) exhibited a marked deficit in postnatal bone acquisition,which was most severe at 3 weeks of age when osteoblast numbers were 12-fold less than observed in control animals. While primary osteoblasts from Nrf22/2mice functioned normally in vitro, the colony forming capacity of bone marrow stromal cells(BMSCs) from these mice was significantly reduced compared to controls.This defect could be rescued through treatment with the radical scavenger N-acetyl cysteine(NAC), suggesting that increased reactive species stress might impair early osteoblastogenesis in BMSCs and lead to the failure of bone acquisition observed in Nrf22/2animals. Taken together, these studies suggest Nrf2 represents a key pathway in regulating bone metabolism, which may provide future therapeutic targets to treat osteoporosis.	Jung-Hyun Kim Vandana Singhal Shyam Biswal Rajesh K Thimmulappa Douglas J Di Girolamo	2014	Bone Research2014，2，4：	3
2	Supercritical carbon dioxid deextraction of caffeine from guarana显示文摘	Mehr C B Biswal R N Collins J L	1996	The Journal of Supererifical Fluids1996，9，3：	1
3	Enhancement of dissolution rate of gliclazide using solid dispersions with polyethylene glycol 6000显示文摘	BISWAL S SAHOO J MURTHY P N	2008	AAPS PharmSciTech2008，9，2：	1
4	Synthesis of silver nanoparticles supported on silica aerogel using gamma radiolysis显示文摘	Ramnani S P Biswal J Sabharwal S	2007	Radiation Physics and Chemistry2007，76，：	1
5	Comparative study of propranolol hydrochloride release from matrix tablets with KollidonSR or hydroxy propyl methyl cellulose显示文摘	Sahoo J Murthy PN Biswal S	2008	AAPS Pharm Sci Tech2008，9，2：	1
6	Analysis of oxygen inhibition in photopolymerizations of hydrogel micropattems using FTIR imaging 显示文摘	Biswal D Hilt J Z	2009	Macromolecules2009，42，4：	1
7	The molecular effects of acrolein 显示文摘	Kehrer J Biswal SS	2000	ToxicolSci2000，57，：	1
8	The molecular effects of acrolein显示文摘	Kehrer J P Biswal S S	2000	Toxicol Sci2000，57，：	1
9	Blind source separation of multiple signal sources of fMRI data sets using independent component a-nalysis显示文摘	Biswal B B Ulmer J L	1999	J Comput Assist Tomogr1999，23，2：	1
10	Microscale analysis of patterning reactions via FTIR imaging: application to intelligent hydrogel systems显示文摘	Biswal D Hilt J Z	2006	Polymer2006，47，21：	1
11	The molecular effects of acrolein显示文摘	Kehrer J Biswal SS	2000	Toxicol Sci2000，57，：	1
12	Application of a recombinant capsid polyprotein (PD expressed in a prokaryotic system to detect antibodies against foot- and-mouth disease virus serotype 0显示文摘	Biswal J K Bisht P Mohapatra J K	2015	J Virol Meth- ods2015，215，：	1
13	Contour-based registration technique to differentiate between task-activated and head motioninduced signal variations in fMRI显示文摘	BISWAL B B HYDE J S	1997	Magnet Reson Med1997，38，：	1
14	Hydrogel Nanocomposites:a Review of Applications as Remote Controlled Biomaterials 显示文摘	Satarkar N S Biswal D Hilt J Z	2010	Soft Matter2010，6，11：	1
15	Supercritical carbon dioxide extraction of caffeine from guarana 显示文摘	Mehr C B Biswal R N Collins J L	1996	The Journal of Supercritical Fluids1996，9，：	1
16	The molecular effects of acrolein显示文摘	Kehrer J H biswal S S	2000	Toxicology science2000，57，：	1
17	Hy- drogel nanocomposites: a Rview of ap- plications as remote controlled bicmateri- als 显示文摘	Satarkar N S Biswal D Hilt J Z	2010	Soft Matter2010，6，11：	1
18	Blind source separation of multiple signal sources of fMRI data sets using Independent component analysis显示文摘	Biswal B B Ulmer J L	1999	Journal of computer assisted tomography1999，23，2：	1
19	Hydrogel nanocomposites:A review of applications as remote controlled biomateri- als显示文摘	Satarkar N S Biswal D Zach Hilt J	2010	Soft Matter2010，6，11：	1
20	Radiation-induced grafting of aerylamide onto guar gum in aqueous medium: Synthesis and characterization of grafted polymer guar-g- acrylamide显示文摘	Biswal J Kumar V Bhardwaj Y K	2007	Radiat Phys Chem2007，76，：	1

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