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| 1 | Global, regional, and national causes of child mortality in 2008: a systematic analysis显示文摘 | Robert E Black Simon Cousens Hope L Johnson Joy E Lawn Igor Rudan Diego G Bassani Prabhat Jha Harry Campbell Christa Fischer Walker Richard Cibulskis Thomas Eisele Li Liu Colin Mathers | 2010 | The Lancet2010，，9730： | 3 |
| 2 | Global, regional, and national causes of child mortality in 2008: a systematic analysis显示文摘 | Robert E Black Simon Cousens Hope L Johnson Joy E Lawn Igor Rudan Diego G Bassani Prabhat Jha Harry Campbell Christa Fischer Walker Richard Cibulskis Thomas Eisele Li Liu Colin Mathers | 2010 | The Lancet . 2010 (9730)2010，，： | 2 |
| 3 | On-chip multiplexed single-cell patterning and controllable intracellular delivery显示文摘Conventional electroporation approaches show limitations in the delivery of macromolecules in vitro and in vivo.These limitations include low efficiency,noticeable cell damage and nonuniform delivery of cells.Here,we present a simple 3D electroporation platform that enables massively parallel single-cell manipulation and the intracellular delivery of macromolecules and small molecules.A pyramid pit micropore array chip was fabricated based on a silicon wet-etching method.A controllable vacuum system was adopted to trap a single cell on each micropore.Using this chip,safe single-cell electroporation was performed at low voltage.Cargoes of various sizes ranging from oligonucleotides(molecular beacons,22 bp)to plasmid DNA(CRISPR-Cas9 expression vectors,>9 kb)were delivered into targeted cells with a significantly higher transfection efficiency than that of multiple benchmark methods(e.g.,commercial electroporation devices and Lipofectamine).The delivered dose of the chemotherapeutic drug could be controlled by adjusting the applied voltage.By using CRISPR-Cas9 transfection with this system,the p62 gene and CXCR7 gene were knocked out in tumor cells,which effectively inhibited their cellular activity.Overall,this vacuum-assisted micropore array platform provides a simple,efficient,high-throughput intracellular delivery method that may facilitate on-chip cell manipulation,intracellular investigation and cancer therapy. | Zaizai Dong Yanli Jiao Bingteng Xie Yongcun Hao Pan Wang Yuanyuan Liu Junfeng Shi Chandani Chitrakar Stephen Black Yu-Chieh Wang LJames Lee Mo Li Yubo Fan Lingqian Chang | 2020 | Microsystems & Nanoengineering2020，6，1： | 2 |
| 4 | Neuronal regulation of alternative pre- mRNA splicing显示文摘 | LI Q LEE J A BLACK D L | 2007 | Nat Rev Neurosci2007，8，11： | 1 |
| 5 | Skeletal muscle cell hypertrophy induced by inhibitors of metalloproteases; myostatin as a potential mediator显示文摘 | Huet C Li ZF Liu HZ Black RA Galliano MF Engvall E | 2001 | Am J Physiol Cell Physiol2001，281，： | 1 |
| 6 | Normal or non-diagnostic neuroimaging studies prior to the detection of malignant primary brain tumors显示文摘 | Thater PB Black KS Li JUet Clin Nertosci M Lsakov Y Demopouios AJ | 2012 | 2012，，： | 1 |
| 7 | Global, regional, and national causes of child mortality: an updated systematic analysis for 2010 with time trends since 2000显示文摘 | Li Liu Hope L Johnson Simon Cousens Jamie Perin Susana Scott Joy E Lawn Igor Rudan Harry Campbell Richard Cibulskis Mengying Li Colin Mathers Robert E Black | 2012 | The Lancet2012，，9832： | 1 |
| 8 | Wavelet-based nonlinear AGC method for hearing aid loudness compensation 显示文摘 | LI M MCALLISTER H G BLACK N D | 2000 | IEEE Proceedings of Vision Image and Signal Processing2000，147，6： | 1 |
| 9 | Global, regional, and national causes of child mortality in 2008: a systematic analysis显示文摘 | Robert E Black Simon Cousens Hope L Johnson Joy E Lawn Igor Rudan Diego G Bassani Prabhat Jha Harry Campbell Christa Fischer Walker Richard Cibulskis Thomas Eisele Li Liu Colin Mathers | 2010 | The Lancet2010，，9730： | 1 |
| 10 | Global, regional, and national causes of child mortality in 2008: a systematic analysis显示文摘 | Robert E Black Simon Cousens Hope L Johnson Joy E Lawn Igor Rudan Diego G Bassani Prabhat Jha Harry Campbell Christa Fischer Walker Richard Cibulskis Thomas Eisele Li Liu Colin Mathers | 2010 | The Lancet2010，，9730： | 1 |
| 11 | An upwelling case study on Florida′s west coast 显示文摘 | Weisberg R H Black B D Li Z | 2002 | Journal of Geophysical Research2002，，11： | 1 |
| 12 | Autophagy is a component of epithelial cell fate in obstructive uropathy 显示文摘 | Li L Zepeda - Orozco D Black R | 2010 | Am J Pathol2010，176，4： | 1 |
| 13 | Autophagy is a component of epithelial cell fate in obstructive uropathy显示文摘 | Li LiZepeda-Orozco D Black R | 2010 | Am J Pathol2010，176，4： | 1 |
| 14 | Wavelet-based nonlinear AGC method for hearing aid loudness compensation显示文摘 | Li M McAllister H G Black N D | 2000 | IEE Proceedings of Vision Image and Signal Processing2000，147，6： | 1 |
| 15 | Analysis of thermal stress-induced grain boundary cavitation and notching in narrow AI-Si metallizations 显示文摘 | Li Cheyu Black Ronald D Lafontaine Willian R | 1988 | Appl Phys Len1988，53，1： | 1 |
| 16 | Global, regional, and national causes of child mortality: an updated systematic analysis for 2010 with time trends since 2000显示文摘 | Li Liu Hope L Johnson Simon Cousens Jamie Perin Susana Scott Joy E Lawn Igor Rudan Harry Campbell Richard Cibulskis Mengying Li Colin Mathers Robert E Black | 2012 | The Lancet2012，，9832： | 1 |
| 17 | Wavelet-based nonlinear AGC method for hearing aid loudness compensation 显示文摘 | Li M McAllister HG Black ND | 2000 | IEEEProceedings-Vision Image and Signal Processing2000，147，6： | 1 |
| 18 | Autophagy is a component of epithelial cell fate in obstructive uropathy 显示文摘 | Li L Zepeda-Orozco D Black R | 2010 | Am J Pathol2010，176，4： | 1 |
| 19 | Co-evolution from yeast to mouse:cDNA cloning of the two NF-Y(CP-1/CBF) sub- units显示文摘 | Van Huijsduijnen R H Li X Y Black D | 1990 | EMBO J1990，9，10： | 1 |
| 20 | Wavelet-based nonlinear AGC method for hearing aid loudness compensation 显示文摘 | Li M McAllister H G Black N D | 2000 | lEE Proceedings of Vision hnage and Signal Processing2000，147，6： | 1 |
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