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| 1 | Photodynamic therapy vs radiofrequency ablation for Barrett's dysplasia: Efficacy,safety and cost-comparison显示文摘AIM:To compare effectiveness,safety,and cost of photodynamic therapy(PDT)and radiofrequency ablation(RFA)in treatment of Barrett’s dysplasia(BD).METHODS:Consecutive case series of patients undergoing either PDT or RFA treatment at single center by a single investigator were compared.Thirty-three patients with high-grade dysplasia(HGD)had treatment with porfimer sodium photosensitzer and 630 nm laser(130 J/cm),with maximum of 3 treatment sessions.Fifty-three patients with BD(47 with low-grade dysplasia-LGD,6 with HGD)had step-wise circumferential and focal ablation using the HALO system with maximum of 4 treatment sessions.Both groups received proton pump inhibitors twice daily.Endoscopic biopsies were acquired at 2 and 12 mo after enrollment,with 4-quadrant biopsies every 1 cm of the original BE extent.A complete histological resolution response of BD(CR-D)was defined as all biopsies at the last endoscopy session negative for BD.Fisher’s exact test was used to assess differences between the two study groups for primary outcomes.For all outcomes,a two-sided P value of less than 0.05 was considered to indicate statistical significance.RESULTS:Thirty(91%)PDT patients and 39(74%)RFA were men(P=0.05).The mean age was 70.7±12.2 and 65.4±12.7(P=0.10)year and mean length of BE was 5.4±3.2 cm and 5.7±3.2 cm(P=0.53)for PDT and RFA patients,respectively.The CR-D was(18/33)54.5%with PDT vs(47/53)88.7%with RFA(P=0.001).One patient with PDT had an esophageal perforation and was managed with non-surgical measures and no perforation was seen with RFA.PDT was five times more costly than RFA at our institution.The two groups were not randomized and had different BD grading are the limitations of the study.CONCLUSION:In our experience,RFA had higher rate of CR-D without any serious adverse events and was less costly than PDT for endoscopic treatment of BD. | Atilla Ertan Irum Zaheer Arlene M Correa Nirav Thosani Shanda H Blackmon | 2013 | World Journal of Gastroenterology2013，19，41： | 7 |
| 2 | On the relationship between tropical and North Pacific sea surface temperature variations显示文摘 | Deser C Blackmon M L | 1995 | Journal of Climate1995，8，6： | 1 |
| 3 | A remote optical system for port and harbor defense显示文摘 | BLACKMON F ANTONELLI L KALINOWSKI A | 2005 | Proc of SPIE2005，，5780： | 1 |
| 4 | Renal cell carcinoma,metastatic to the left ventricle显示文摘 | Aburto J Bruckner BA Blackmon SH | 2009 | Tex Heart Inst J2009，36，1： | 1 |
| 5 | QTc prolongation associated with combination therapy of levofloxacin, imipramine, and fluoxetine显示文摘 | Nykamp D L Blackmon C L Schmidt P E | 2005 | Ann Pharmacother2005，39，3： | 1 |
| 6 | Cardiac autotransplantation for malignant or complex primary left-heart tumors显示文摘 | Blackmon SH Patel AR Bruckner BA | | 0，，03： | 1 |
| 7 | Hypothermia:a neuroprotective therapy for neonatal hypoxic-ischemie encephalopathy显示文摘 | Blackmon LR Stark AR American Academy of Pediatrics Committee on Fetus and Newborn | 2006 | Pediatries2006，117，3： | 1 |
| 8 | Single sperm cryopreservation on cryoloops:an alternative to hamster zona for freezing individual spermatozoa 显示文摘 | Desai NN Blackmon H Goldfarb J | 2004 | Reprod Biomed Online2004，9，1： | 1 |
| 9 | Supercharged pedicled jejunal interposition for esophageal replacement:a 10-year experience显示文摘 | Blackmon S H Correa A M Skoracki R Chevray P M Kim M P Mehran R J | 2012 | Ann Thorac Surg2012，94，： | 1 |
| 10 | A climatological spectral study of the 500 mb geopotential height of the Northern Hemisphere显示文摘 | BLACKMON M L | 1976 | J Atmos Sci1976，33，8： | 1 |
| 11 | Pulmonary nocardiosis : computed tomography features at diagnosis 显示文摘 | Blackmon K N Ravenel J G Gomez J M | 2011 | J Thorac Imaging2011，26，3： | 1 |
| 12 | Thulium Fiber Laser Lithotripsy Using Tapered Fibers 显示文摘 | BLACKMON R L IRBY P B FRIED N M | 2010 | Lasers in Surgery and Medicine(S0196-8092)2010，42，： | 1 |
| 13 | Congenital iris coloboma repair u- sing a modified McCannel suture technique 显示文摘 | Blackmon DM Lambert SR | 2003 | Am J Ophthal- mo/2003，135，5： | 1 |
| 14 | Storage: High- availability file server with heartbeat显示文摘 | BLACKMON S NGUYEN J | 2001 | System Administrators2001，10，9： | 1 |
| 15 | A general circulation model study of January climate anomalous Patterns associated with interannual variation of equatorial Pacific sea surface Temperature显示文摘 | Blackmon M L | 1983 | J Atmos Sci1983，40，6： | 1 |
| 16 | Esophageal salvage with removable covered self-expanding metal stents in the setting of intrathoracic esophageal leakage 显示文摘 | David EA Kim MP Blackmon SH | 2011 | Am J Surg2011，202，6： | 1 |
| 17 | Research on prevention of bilirubin-induced brain injury and kernicterus显示文摘 | Lillian R Blackmon Avroy A | 2004 | Pediatrics2004，114，1： | 1 |
| 18 | Remote,aerial,opto-acoustic communication and sonar显示文摘 | BLACKMON F ANTONELLI L | 2005 | SPIE2005，5778，： | 1 |
| 19 | Spirals of Silence: The Dynamic Effects of Diversity on Organizational Voice显示文摘 | Bowen F Blackmon K | 2003 | Journal of Management Studies2003，40，6： | 1 |
| 20 | Experimental detection and reception performance for uplink underwater acoustic communication using a remote, in-air, acousto-optic sensor 显示文摘 | Blackmon F A Antonelli L T | 2006 | Oceanic Engineering IEEE Journal of2006，31，1： | 1 |
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