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| 1 | Not Ready for Convergence in Data Infrastructures显示文摘Much research is dependent on Information and Communication Technologies(ICT).Researchers in different research domains have set up their own ICT systems(data labs)to support their research,from data collection(observation,experiment,simulation)through analysis(analytics,visualisation)to publication.However,too frequently the Digital Objects(DOs)upon which the research results are based are not curated and thus neither available for reproduction of the research nor utilization for other(e.g.,multidisciplinary)research purposes.The key to curation is rich metadata recording not only a description of the DO and the conditions of its use but also the provenance-the trail of actions performed on the DO along the research workflow.There are increasing real-world requirements for multidisciplinary research.With DOs in domain-specific ICT systems(silos),commonly with inadequate metadata,such research is hindered.Despite wide agreement on principles for achieving FAIR(findable,accessible,interoperable,and reusable)utilization of research data,current practices fall short.FAIR DOs offer a way forward.The paradoxes,barriers and possible solutions are examined.The key is persuading the researcher to adopt best practices which implies decreasing the cost(easy to use autonomic tools)and increasing the benefit(incentives such as acknowledgement and citation)while maintaining researcher independence and flexibility. | Keith Jeffery Peter Wittenburg Larry Lannom George Strawn Claudia Biniossek Dirk Betz Christophe Blanchi | 2021 | Data Intelligence2021，3，1： | 7 |
| 2 | Endoscopic mucosal resection for high-grade dysplasia and intramucosal carcinoma in Barrett's esophagus: An Italian experience显示文摘AIM: To evaluate endoscopic mucosal resection (EMR)in patients with high-grade dysplasia (HGD) and/or intramucosal cancer (IMC) in Barrett's esophagus (BE).METHODS: Between June 2000 and December 2003,39 consecutive patients with HGD (35) and/or IMC (4)underwent EMR. BE >30 mm was present in 27 patients.In three patients with short segment BE (25.0%), HGDwas detected in a normal appearing BE. Lesions had a mean diameter of 14.8±10.3 mm. Mucosal resection was carried out using the cap method.RESULTS: The average size of resections was 19.7±9.4×14.6±8.2 mm. Histopathologic assessment postresection revealed 5 low-grade dysplasia (LGD) (12.8%),27 HGD (69.2%), 2 IMC (5.1%), and 5 SMC (-12.8%).EMR changed the pre-treatment diagnosis in 10 patients (25.6%). Three patients with SMC underwehtsurgery.Histology of the surgical specimen revealed 1 T0N0 and 2 T1N0 lesions. The remaining two patients were cancer free at 32.5 and 45.6 mo, respectively. A metachronous lesion was detected after 25 mo in one patient with HGD. Intra-procedural bleeding, controlled at endoscopy,occurred in four patients (10.3%). After a median followup of 34.9 mo, all patients remained in remission.CONCLUSION: In the medium term, EMR is effective and safe to treat HGD and/or IMC within BE and is a valuable staging method. It could become an alternative to surgery. | Massimo Conio Alessandro Repici Renzo Cestari Sabrina Blanchi Gabriella Lapertosa Guido Missale Domenico Della Casa Vincenzo Villanacci Pier Gigi Calandri Rosangela Filiberti | 2005 | World Journal of Gastroenterology2005，11，42： | 6 |
| 3 | Acute small bowel obstruction caused by endometriosis:A case report and review of the literature显示文摘Gastrointestinal involvement of endometriosis has been found in 3%-37% of menstruating women and exclusive localization on the ileum is very rare(1%-7%).Endometriosis of the distal ileum is an infrequent cause of intestinal obstruction,ranging from 7% to 23% of all cases with intestinal involvement.We report a case in which endometrial infiltration of the small bowel caused acute obstruction requiring emergency surgery,in a woman whose symptoms were not related to menses.Histology of the resected specimen showed that endometriosis was mainly prevalent in the muscularis propria and submucosa and that the mucosa was not ulcerated but had inflammation and glandular alteration.Endometrial lymph node involvement,with a cystic glandular pattern was also detected. | Antonella De Ceglie Claudio Bilardi Sabrina Blanchi Massimo Picasso Massimo Conio Marcello Di Muzio Alberto Trimarchi | 2008 | World Journal of Gastroenterology2008，14，21： | 5 |
| 4 | Endoscopic management of GI perforations with a new over-the-scope clip device (with videos)显示文摘 | Andrea Parodi Alessandro Repici Antonietta Pedroni Sabrina Blanchi Massimo Conio | 2010 | Gastrointestinal Endoscopy2010，，4： | 3 |
| 5 | Polyflex stents for malignant oesophageal and oesophagogastric stricture: a prospective, multicentric study显示文摘 | Rita Conigliaro Giorgio Battaglia Alessandro Repici Giovanni De Pretis Luigi Ghezzo Max Bittinger Helmut Messmann Jean-Fran?ois Demarquay Michele Togni Sabrina Blanchi Rosangela Filiberti Massimo Conio | 2007 | European Journal of Gastroenterology & Hepatology2007，，3： | 2 |
| 6 | Distributed interoperable metadataregistry显示文摘 | BLANCHI C PETRONE J | 2001 | D-Lib Magazine2001，7，12： | 1 |
| 7 | Endoscopic mucosal resec- tion显示文摘 | Conio M Ponchon T Blanchi S | 2006 | Am J Gastroenterol2006，101，3： | 1 |
| 8 | Microporous thermally sensitive hydrogels based on hydroxypropyl cellulose crosslinked with poly-ethyleneglicol diglycidyl ether显示文摘 | MARSANO E BLANCHI E SCIUTFO L | 2003 | Polymer2003，44，22： | 1 |
| 9 | International Autoimmune Hepatitis Group Report: review of criteria for diagnosis of autoimmune hepatitis 显示文摘 | Alvarez F Berg PA Blanchi FB | 1999 | J Hepato1999，31，5： | 1 |
| 10 | Microporous and mesoporous materials for the treatment of wastewater produced by petrochemical activities显示文摘 | Moreno Maretto Federica Blanchi Rodolfo Vignola | 2014 | Journal of Cleaner2014，77，15： | 1 |
| 11 | Self-expanding plastic stent to palliate symptomatic tissue in/overgrowth after self-expanding metal stent placement for esopha- geal cancer 显示文摘 | Conio M Blanchi S Filiberti R | 2010 | Dis Esophagus2010，23，7： | 1 |
| 12 | Quantification of green fluorescent protein by in vivo imaging,PCR,and flow cytometry:comparison of transgenic strains and relevance for fetal cell microchimerism显示文摘 | Fujiki Y Tao K Blanchi DW | 2008 | Cytometry A2008，73，2： | 1 |
| 13 | The secretion of HMGB1 is required far the migration of maturing dendritic cells显示文摘 | Dumitriu IE Blanchi ME Bacci M | 2007 | J Leukoc Biol2007，81，1： | 1 |
| 14 | beLi expanding plastic stent to palliate symptomatic tissue in/overgrowth after self-expanding metal stent place- ment for esophageal cancer显示文摘 | CONIO M BLANCHI S FILIBERT1 R | 2010 | Dis Esophagus2010，23，7： | 1 |
| 15 | A randomized, double blind, clinical trial comparing the efficacy of nimesulide, celecoxib and rofecoxid in os- teoarthritis of the knee显示文摘 | Blanchi M Broggini M | 2003 | Drugs2003，63，10： | 1 |
| 16 | MafB is required for islet beta cell maturation显示文摘 | BLANCHI B RAUM J C | 2007 | Proc Natl Acad Sci USA2007，104，10： | 1 |
| 17 | CD133 + neural stem cells in the ependyma of mammalian postnatal fore- brain 显示文摘 | Coskun V Wu H Blanchi B | 2008 | Proc Natl Acad Sci U S A2008，105，： | 1 |
| 18 | The secretion of HMGB1 is required for the migration of maturing dendritic cells 显示文摘 | Dumitriu IE Blanchi ME Bacci M | 2007 | J Leukoc Bio12007，81，1： | 1 |
| 19 | An Architecture for Information in Digital Libraries显示文摘 | William Y Arms Christophe Blanchi Edward A Overly | 1997 | D-Lib Magazine1997，02，： | 1 |
| 20 | Metal stents in the cervical esophagus显示文摘 | Conio M Blanchi S Munizzi F | 2002 | Gastrointest Endosc2002，55，7： | 1 |
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