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| 1 | Concurrent use of aromatase inhibitors and hypofractionated radiation therapy显示文摘AIM: To retrospectively assess the acute and long-term toxicity using aromatase inhibitors (AI) therapy concurrently with hypofractionated radiotherapy (HFRT) in breast cancer patients. METHODS: From November 1999 to October 2007, 66 patients were treated with breast HFRT and concurrent AI. In 63 patients (95.5%), HFRT delivered a total dose of 32.5 Gy to the whole breast within 5 wk (five fractions, one fraction per week). Other fractionations were chosen in three patients for the patients' personal convenience. A subsequent boost to the tumor bed was delivered in 35 patients (53.0%). Acute toxicities were scored according to the Common Toxicity Criteria for Adverse Events v3. Late toxicity was defined as any toxicity occurring more than 6 mo after completion of HFRT and was scored according to the Late Effects Normal Tissue Task Force-Subjective, Objective, Management and Analytic scale. RESULTS: At the end of the HFRT course, 19 patients (28.8%) had no irradiation-related toxicity. Acute grade 1-2 epithelitis was observed in 46 patients (69.7%). One grade 3 toxicity (1.5%) was observed. With a median follow-up of 34 mo (range: 12-94 mo), 31 patients (47%) had no toxicity, and 35 patients (53%) presented with grade 1-2 fibrosis. No grade 3 or greater delayed toxicity was observed. CONCLUSION: We found that AI was well tolerated when given concurrently with HFRT. All toxicities were mild to moderate, and no treatment disruption was necessary. Further prospective assessment is warranted. | Cyrus Chargari Pablo Castro-Pena Ivan Toledano Marc A Bollet Alexia Savignoni Paul Cottu Fatima Laki Franois Campana Patricia De Cremoux Alain Fourquet Youlia M Kirova | 2012 | World Journal of Radiology2012，4，7： | 2 |
| 2 | Postoperative brachytherapy alone and combined postoperative radiotherapy and brachytherapy boost for squamous cell carcinoma of the oral cavity, with positive or close margings 显示文摘 | Lapeyre M Bollet MA Racadot S | 2004 | Head Neck2004，26，3： | 1 |
| 3 | Targeting poly(ADP-ribose) polymerase activity for cancer therapy显示文摘 | Megnin-Chanet F Bollet M A Hall J | 2010 | Cell Mol Life Sci2010，67，21： | 1 |
| 4 | 16S ribosomal DNA sequence analysis of a large collection of environmental and clinical unidentifiable bacterial isolates 显示文摘 | Drancourt M Bollet C Carlioz A | 2000 | J Clin Microbiol2000，38，10： | 1 |
| 5 | 16S ribosomal DNA sequence analysis of a large collection of environmental and clinical unidentifiable bacterial isolates 显示文摘 | Dranourt M Bollet C Carlioz R | 2000 | Clin Microbiol2000，38，： | 1 |
| 6 | Pathological response to preoperative concurrent chemo-radiotherapy for breast cancer:Results of a phase Ⅱ study显示文摘 | Bollet M A Sigal-Zafrani B Gambotti L | 2006 | Eur J Cancer2006，42，14： | 1 |
| 7 | 16S ribosomal DNA sequence analysis of a large collection of environmental and clinical unidentifiable bacterial isolates 显示文摘 | Drancourt M Bollet C Carlioz R | 2000 | J Clin Microbiol2000，38，10： | 1 |
| 8 | Radiotherapy treatment planning of prostate cancer using magnetic resonance imaging alone显示文摘 | Lee YK Bollet M Charles-Edwards G | 2003 | Radiother Oncol2003，66，2： | 1 |
| 9 | 16SribosomalDNA sequence analysis of a large collection environ-mental and clinical unidentifiable bacterial isolates显示文摘 | Drancourt M Bollet C Carlioz R | 2000 | Clin Microbiol2000，38，： | 1 |
| 10 | 16S ribosomal DNA sequence analysis of a large collection of environmental and clinical unidentifiable bacterial isolates显示文摘 | Drancourt M Bollet C Carlioz R | 2000 | J Clin Microbiol2000，38，： | 1 |
| 11 | Radiotherapy treatment planning of prostate cancer using magnetic resonance imaging alone显示文摘 | Lee YK Bollet M Edwards GH | 2003 | Radiother Oncol2003，669，2： | 1 |
| 12 | Cardiac toxicity in breast cancer patients:From a fractional point of view to a global assessment显示文摘 | CHARGARI C KIROV K M BOLLET M A | 2011 | Can Treat Rev2011，37，4： | 1 |
| 13 | 16S ribosomal DNA sequence analysis of a large collection of envi- ronmental and clinical unidentifiable bacterial isolates 显示文摘 | Drancourt M Bollet C Carlioz R | 2000 | J Clin Microbiol2000，38，： | 1 |
| 14 | Effect of hypoxia on muscular performance capacity: Living Low-Training High 显示文摘 | VOGT M BOLLETER R HOPPELER H | 2003 | Ther Umsch2003，60，7： | 1 |
| 15 | 16S ribosomal DNA sequence analysis of a large collection of environmental and clinical unidentifiable bacterial isolates显示文摘 | DRANCOURT M BOLLET C CARLIOZ A | 2000 | J Clin Microbiol2000，38，10： | 1 |
| 16 | 16S ribosomal DNA sequence analysis of a large collection of environmental and clinical Unidentifiable bacterial isolations显示文摘 | DRANCOURT M BOLLET A | 2000 | Clin Microbio12000，10，： | 1 |
| 17 | 16S ribosomal DNA sequence analysis of a large collection of environ- mental and clinical unidentifiable bacterial isolates 显示文摘 | Drancourt M Bollet C Carlioz R | 2000 | Journal of Clinical Microbiology2000，38，10： | 1 |
| 18 | 16Sribosomal DNA sequence analysis of a large collection of environmental and clinical unidentifiable bacterial isolates显示文摘 | Drancourt M Bollet C Carlioz R | 2000 | Clin Microbiol2000，38，： | 1 |
| 19 | Radiotherapy treatment planning of prostate cancer using magnetic resonance imaging alone显示文摘 | Lee Y K Bollet M Charles - Edwards G | 2003 | Radiother Oncol2003，66，2： | 1 |
| 20 | Postoperative brachytherapy boost for squamous cell carcinoma of the oral cavity with positive or close margins显示文摘 | Lapeyre M Bollet MA Racadot S | | 0，，： | 1 |
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