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| 1 | 2018加拿大心境障碍与焦虑障碍治疗协作组/国际双相障碍学会指南:双相障碍的管理显示文摘加拿大心境障碍与焦虑障碍治疗协作组(Canadian Network for Mood and Anxiety Treatments,CANMAT)曾于2005年发布了第1版双相障碍管理指南,并分别于2007、2009和2013年对该指南进行了更新,其中最近的2次更新是与国际双相障碍学会(International Society for Bipolar Disorders,ISBD)合作完成。2018版CANMAT/ISBD双相障碍治疗指南(以下简称指南)反映了自2005年首版指南发表以来本领域取得的重大进展,包括疾病诊断与疾病管理的更新以及药物治疗与心理治疗的近期研究进展。这些前沿进展中综合考虑了循证证据的级别,并基于治疗疗效、临床实践经验、安全性、耐受性和药物导致的转相风险等,对一线、二线及三线治疗方案进行了简明而清晰的推荐。本指南中新增内容涵盖了双相Ⅰ型障碍(BD-Ⅰ)的躁狂发作急性期、抑郁发作急性期和双相障碍维持期的一线及二线治疗推荐等级划分。这种对治疗推荐等级的划分综合考虑了治疗方法对双相障碍不同时相的影响,将进一步帮助临床医生做出基于循证证据的治疗决策。锂盐、喹硫平、双丙戊酸盐、阿塞那平、阿立哌唑、帕利哌酮、利培酮和卡利拉嗪单药或联合使用被推荐为躁狂发作急性期的一线治疗选择。BD-Ⅰ抑郁期的一线治疗选择包括喹硫平、鲁拉西酮、锂盐、拉莫三嗪单药,鲁拉西酮联合锂盐或双丙戊酸盐或拉莫三嗪辅助治疗。尽管急性期治疗有效的药物通常应继续用于BD-Ⅰ的维持期治疗,但也存在一些特殊情况(例如抗抑郁药)。现有数据表明,锂盐、喹硫平、双丙戊酸盐、拉莫三嗪、阿塞那平和阿立哌唑单药或联合治疗应被视为维持治疗的初始或更换治疗方案时的一线选择。除了探讨BD-Ⅰ的相关问题外,本指南中还对双相Ⅱ型障碍(BD-Ⅱ)的临床管理进行了系统回顾并给予治疗推荐,同时针对特殊人群也有相关推荐,如处于各个生殖周期的女性、儿童、青少年和老年人。此外,本指南中还讨论了特定精神疾病及共病(如物质滥用、焦虑障碍和代谢性疾病)的影响。最后,本指南中概述了安全性和药物监测的相关问题。CANMAT/ISBD工作组希望本指南能够成为全球临床医生的实用工具。 | Lakshmi N Yatham Sidney H Kennedy Sagar V Parikh Ayal Sehaffer David J Bond Benicio N Frey Verinder Sharma Benjamin I Goldstein Soham Rej Serge Beaulieu Martin Alda Glenda MaeQueen Roumen V Milev Arun Ravindran Claire O'Donovan Diane Mclntosh Raymond W Lam Gustavo Vazquez Flavio Kapczinski Roger S Melntyre Jan Kozicky Shigenobu Kanba Beny Lafer Trisha Suppes Joseph R Calabrese Eduard Vieta Gin Malhi Robert M Post Michael Berk 胡晨(译) 王刚(译) | 2019 | 中华精神科杂志2019，52，1： | 25 |
| 2 | Choledochal cysts: Similarities and differences between Asian and Western countries显示文摘Choledochal cysts(CCs)are rare bile duct dilatations,intra-and/or extrahepatic,and have higher prevalence in the Asian population compared to Western populations.Most of the current literature on CC disease originates from Asia where these entities are most prevalent.They are thought to arise from an anomalous pancreaticobiliary junction,which are congenital anomalies between pancreatic and bile ducts.Some similarities in presentation between Eastern and Western patients exist such as female predominance,however,contemporary studies suggest that Asian patients may be more symptomatic on presentation.Even though CC disease presents with an increased malignant risk reported to be more than 10%after the second decade of life in Asian patients,this risk may be overstated in Western populations.Despite this difference in cancer risk,management guidelines for all patients with CC are based predominantly on observations reported from Asia where it is recommended that all CCs should be excised out of concern for the presence or development of biliary tract cancer. | George N Baison Morgan M Bonds William S Helton Richard A Kozarek | 2019 | World Journal of Gastroenterology2019，25，26： | 16 |
| 3 | ES-cell derived hematopoietic cells induce transplantation tolerance显示文摘 | Bonde S Chan KM Zavazava N | 2008 | PloS ONE2008，3，9： | 1 |
| 4 | Introduction : self-healing polymers and composites 显示文摘 | Sottos N White S Bond I | 2007 | Journal of The Royal Society Interface2007，4，13： | 1 |
| 5 | Using a Delphi approach to identify managers' preferences for visitor interpretation at Canterbury Cathedral World Heritage Site显示文摘 | BALLANrTYNE R HUGHES K BOND N | 2016 | Tourism Management2016，28，2： | 1 |
| 6 | Uncertainty and Investment Dynamics 显示文摘 | Bloom N Bond S Van Reenen J | 2007 | The Review of Economic Studies2007，74，2： | 1 |
| 7 | Synthesis and prelimi-nary evaluation of some pyrazine containing thiazolinesand thiazolidinones as antimicrobial agents 显示文摘 | BONDE C G GAIKWAD N J | 2004 | Bioorg Med Chem2004，12，： | 1 |
| 8 | Atmospheric forcing of the southeast Bering Sea Shelf during 1995-99 in the context of a 40-year historical record显示文摘 | Bond N A Adams J M | 2002 | Deep-Sea Research2002，49，： | 1 |
| 9 | Australian futures:Aquatic ecosystems and human water usage显示文摘 | Lake P S Bond N R | | 0，，39： | 1 |
| 10 | Upperocean response to typhoon Choi-Wan as measured by theKuroshio extension observatory mooring显示文摘 | BOND N A CRONIN M F SABINE C | 2011 | J GeophysRes2011，116，2： | 1 |
| 11 | Plant cyclotides: A uniquefamily of cyclic and knotted proteins that defines the cyclic cystineknot structural motif 显示文摘 | Craik D J Daly N L Bond T | 1999 | J Mol Biol1999，294，13： | 1 |
| 12 | Phthalates and Perfluorooctanesulfonic Acid in Human Amniotic Fluid: Temporal Trends and Timing of Amniocentesis in Pregnancy显示文摘 | Jensen Morten S?ndergaard N?rgaard-Pedersen Bent Toft Gunnar Hougaard David M Bonde Jens Peter Cohen Arieh Thulstrup Ane Marie Ivell Richard Anand-Ivell Ravinder Lindh Christian H J?nsson Bo A G | 2012 | EN2012，，6： | 1 |
| 13 | High frequency of multiple HPV types in cervical specimens from Danish women 显示文摘 | Mejlhede N Bonde J Fomsgaard A | 2009 | APMIS2009，117，： | 1 |
| 14 | The hydraulic limitation hypothesis revisited显示文摘 | RYAN M G PHILIPS N BOND B J | 2006 | Plant Cell and Environment2006，29，3： | 1 |
| 15 | Mannan-binding leetin and healing of a radiation-induced chronic uleer-a case report on mannan-binding lectin replacement therapy 显示文摘 | Maaloe N Bonde C Laursen I | 2011 | J Plast Reconstr Aesthet Surg2011，64，6： | 1 |
| 16 | Uncertainty and investment dynamies显示文摘 | BLOOM N BOND S : 2007 | 2007 | The review of economic studies2007，74，2： | 1 |
| 17 | Evidence for general instability of past climate from a 250-kyr ice-core record显示文摘 | Dansgaard W Johnsen S J Clausen H B Dahl-Jensen D Gundestrup N S Hammer C U Hvidberg C S Steffensen J P Sveinbj rnsdottir A E Jouzel J Bond G | | 0，，： | 1 |
| 18 | Introduction: Self-healing polymers and composites显示文摘 | Sottos N White S Bond I | 2007 | J Royal So c lnterf2007，4，： | 1 |
| 19 | The Drosophila melanogaster actin 5C gene uses two transcription initiation sites and three polyadenylation sites to express multiple mRNA species显示文摘 | Bond BJ Davidson N | 1986 | Mol Cell Biol1986，6，6： | 1 |
| 20 | Endoscopic vein harvest:advantages and limitations显示文摘 | Bonde P Graham A N MacGowan S W | 2004 | Ann Thorac Surg2004，77，6： | 1 |
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