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| 1 | Multipurpose use of the over-the-scope-clip system(“Bear claw”) in the gastrointestinal tract:Swiss experience in a tertiary center显示文摘AIM:To evaluate the outcome of over-the-scope-clip system(OTSC)for endoscopic treatment of various indications in daily clinical practice in Switzerland.METHODS:This prospective,consecutive case series was conducted at a tertiary care hospital from September 2010 to January 2014.Indications for OTSC application were fistulae,anastomotic leakage,perforation,unroofed submucosal lesion for biopsy,refractory bleeding,and stent fixation in the gastrointestinal(GI)tract.Primary technical success was defined as the adequate deployment of the OTSC on the target lesion.Clinical success was defined as resolution of the problem;for instance,no requirement for surgery or further endoscopic intervention.In cases of recurrence,retreatment of a lesion with a second intervention was possible.Complications were classified into those related to sedation,endoscopy,or deployment of the clip.RESULTS:A total of 28 OTSC system applications werecarried out in 21 patients[median age 64 years(range42-85),33%females].The main indications were fistulae(52%),mostly after percutaneous endoscopic gastrostomy tube removal,and anastomotic leakage after GI surgery(29%).Further indications were unroofed submucosal lesions after biopsy,upper gastrointestinal bleeding,or esophageal stent fixation.The OTSC treatments were applied either in the upper(48%)or lower(52%)GI tract.The mean lesion size was 8 mm(range:2-20 mm).Primary technical success and clinical success rates were 85%and 67%,respectively.In53%of cases,the suction method was used without accessories(e.g.,twin grasper or tissue anchor).No endoscopy-related or OTSC-related complications were observed.CONCLUSION:OTSC is a useful tool for endoscopic closure of various GI lesions,including fistulae and leakages.Future randomized prospective multicenter trials are warranted. | Michael Christian Sulz Reto Bertolini Remus Frei Gian-Marco Semadeni Jan Borovicka Christa Meyenberger | 2014 | World Journal of Gastroenterology2014，20，43： | 17 |
| 2 | Genetic Variation in IL28B Is Associated With Chronic Hepatitis C and Treatment Failure: A Genome-Wide Association Study显示文摘 | Andri Rauch Zoltán Kutalik Patrick Descombes Tao Cai Julia Di Iulio Tobias Mueller Murielle Bochud Manuel Battegay Enos Bernasconi Jan Borovicka Sara Colombo Andreas Cerny Jean–Fran?ois Dufour Hansjakob Furrer Huldrych F. Günthard Markus Heim Bernard Hirs | 2010 | Gastroenterology2010，，4： | 2 |
| 3 | Hyperaceumulation of silver by Amanita strobiformis and related species of the section Lepidella 显示文摘 | Borovicka J Randa Z Jelinek E | 2007 | Mycological Research2007，111，11： | 1 |
| 4 | Autofluorescence endoscopy in surveillance of Barrett'sesophagus:a multicenter randomized trial on diagnosticefficacy显示文摘 | Borovicka J Fischer J Neuweiler J | 2006 | Endoscopy2006，38，9： | 1 |
| 5 | Effect of lintitript,a new CCK-A receptor antagonist,on gastric emptying of a solid ~liquid meal in humans显示文摘 | Sch Wzzer W Borovicka J | 1998 | regual Pept1998，30，： | 1 |
| 6 | Cytomegalovirus induced transient protein-losing hypertrophic gastropathy in an immunocom petent adult显示文摘 | Suter WR Neuweiler J Borovicka J | 2000 | Digestion2000，62，： | 1 |
| 7 | Measurement of proximal and distal gastric motility with magnetic resonance image显示文摘 | Schwizer W Fraser R Borovicka J | 1996 | Am J Physiol1996，271，11： | 1 |
| 8 | 显示文摘 | Schwizer W Fraser R Borovicka J | 1994 | Dig Dis Sci1994，39，： | 1 |
| 9 | 显示文摘 | Schwizer W Fraser R Borovicka J | 1996 | Am J Physiol1996，271，： | 1 |
| 10 | Lapambcopic Mesh-augmented hiatnplasty as a treatment of gastroesophageal refluxdisease and hiatal hernias preliminary clinical and functional resultsof a prospective case series显示文摘 | Moiler Stich BP Linke GR Borovicka J | 2008 | Am J Surg2008，195，6： | 1 |
| 11 | Hyperaccumulation of silver by Amanita strobiliformis and related species of the section Lepidella显示文摘 | Borovicka J Randa Z Jelinek E | 2007 | Mycological Research2007，111，11： | 1 |
| 12 | Measurement of proximal and distal gastric motility with magnetic resonance imaging显示文摘 | Schwizer W Fraser R Borovicka J | 1996 | Am J Physiol1996，271，： | 1 |
| 13 | Clinical severity does not reliably predict quality of life in women with alopecia areata,telogen effluvium,or androgenic alopecia显示文摘 | Reid EE Haley AC Borovicka JH | 2012 | JAAD2012，66，： | 1 |
| 14 | Macro and trace mineral con- stituents and radionuclides in mushrooms-health benefits and risks显示文摘 | Falandysz J Borovicka J | 2013 | Applied Microbiology and Biotechnology2013，97，2： | 1 |
| 15 | Macro and trace mineral constituents and mdionuclides in mushrooms: health benefits and risks 显示文摘 | FALANDYSZ J BOROVICKA J | 2013 | Appl Microbiol Biotechnol2013，92，2： | 1 |
| 16 | Is a barium swallow complementary to endoscopy essential in the preoperative assessment of laparoscopic antireflux and hiatal hernia surgery显示文摘 | Linke GR Borovicka J Schneider P | 2008 | Surg Endosc2008，22，1： | 1 |
| 17 | Clinical severity does not reliably predict quality of life in women with alopecia areata,telogen effluvium,or androgenic alopecia显示文摘 | Reid EE Haley AC Borovicka JH | 2012 | J Am Acad Dermatol2012，66，3： | 1 |
| 18 | Ablation of the otcC gene encoding a postpolyketide hydroxylase from the oxytetracyline biosynthetic pathway in Streptomyces rimosus results in novel polyketides with altered chain length 显示文摘 | Peric-Concha N Borovicka B Long P F | 2005 | J Biol Chem2005，280，37： | 1 |
| 19 | Laparoscopic mesh-augmented hiatoplasty as a treatment of gastroesophageal re- flux disease and hiatal hernias-preliminary clinical and fmlctional sults of a prospective case series 显示文摘 | Mtiller-Stich BP Linke GR Borovicka J el al | 2008 | Am J Surg2008，195，6： | 1 |
| 20 | Genetic Variation in IL28B Is Associated With Chronic Hepatitis C and Treatment Failure: A Genome-Wide Association Study显示文摘 | Andri Rauch Zoltán Kutalik Patrick Descombes Tao Cai Julia Di Iulio Tobias Mueller Murielle Bochud Manuel Battegay Enos Bernasconi Jan Borovicka Sara Colombo Andreas Cerny Jean–Fran?ois Dufour Hansjakob Furrer Huldrych F. Günthard Markus Heim Bernard Hirs | 2010 | Gastroenterology2010，，4： | 1 |
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