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20篇 您的检索式:作者名="Borschitz"
    题名 作者 年代 出处 被引量
1Coexpression of receptor-tyrosine-kinases in gastric adenocarcinoma-a rationale for a molecular targeting strategy?显示文摘AIM: To define the (co-)expression pattern of target receptor-tyrosine-kinases (RTK) in human gastric adenocarcinoma. METHODS: The (co-)expression pattern of VEGFR1-3,PDGFRα/b and EGFR1 was analyzed by RT-PCR in 51 human gastric adenocarcinomas. In addition,IHC staining was applied for confirmation of expression and analysis of RTK localisation. RESULTS: The majority of samples revealed a VEGFR1 (98%),VEGFR2 (80%),VEGFR3 (67%),PDGFRα (82%) and PDGFRβ(82%) expression,whereas only 62% exhibited an EGFR1 expression. 78% of cancers expressed at least four out of six RTKs. While VEGFR1-3 and PDGFRα revealed a predominantly cytoplasmatic staining in tumor cells,accompanied by an additional nuclear staining for VEGFR3 ,EGFR1 was almost exclusively detected on the membrane of tumor cells. PDGFRβ was restricted to stromal pericytes,which also depicted a PDGFRα expression.receptor-tyrosine-kinases coexpression in gastric adenocarcinoma and might therefore encourage an application of multiple-target RTK-inhibitors within a combination therapy.Daniel Drescher Markus Moehler Ines Gockel Kirsten Frerichs Annett Müller Friedrich Dünschede Thomas Borschitz Stefan Biesterfeld Martin Holtmann Thomas Wehler Andreas Teufel Kerstin Herzer Thomas Fischer Martin R Berger Theodor Junginger Peter R Galle Carl C Schimanski 2007World Journal of Gastroenterology2007,13,26:4
2The intluevtce of histopathologic criteria on the long--term prognosis of locally excised pWl rectal carcinomas: results of local exci--sion (transanal endoscopic microsurgery) and immediate reoperation显示文摘Borschitz T Hemtz A Junginger T 2006Dis Col --on Rectum2006,49,10:1
3Progress report about the 1st workshop on localexcision of rectal cancer显示文摘Borschitz T Junginger T 2007Zentralbl Chir2007,132,2:1
4The influence of histopathologic criteria on the long-term prognosis of locally excised pTl rectal carcinomas: results of local excision (transanal endoscopic microsurgery ) and immediate reoperation 显示文摘Borschitz T Heintz A Junginger T 2006Dis Colon Rectum2006,49,10:1
5Neoadjuvant chemoradiation and local excision for T2-3 rectal cancer 显示文摘Borschitz T Wachtlin D Mohler M 2008Ann Surg Oncol2008,15,3:1
6Neoadjuvant chemoradiation and local excision for T2-3 rectal cancer显示文摘Borschitz T Wachtlin D Mohler M 2008Ann Surg Oncol2008,15,3:1
7Neoadjuvant chemo- radiation and local excision for T2-3 rectal cancer 显示文摘Borschitz T Waehtlin D Mohler M 2008Ann Surg Oncol2008,15,3:1
8Neoadjuvant chemoradiationand local excision for T2-3 rectal cancer显示文摘Borschitz T Wachtlin D Mohler M 0,,03:1
9Neoadjuvant Chemoradiation and Local Excision for T2-3 Rectal Cancer显示文摘Thomas Borschitz MD Daniel Wachtlin Markus M?hler MD Heinz Schmidberger MD Theodor Junginger MD 2008Annals of Surgical Oncology2008,,3:1
10Local excision for more advanced rectal tumors显示文摘Borschitz T Kneist W Gockel I 2008Acta Oncol2008,47,6:1
11Neoadjuvant chemoradiation and local excision for T2-3 rectal cancer显示文摘Borschitz T Wachtlin D M(o)hler M 2008Ann Surg Oncol2008,15,:1
12The influence of histopathologic criteria on the long-term prognosis of locally excised pT1 rectal carcinomas: results of local excision (transanal endoscopic microsurgery ) and immediate reoperation 显示文摘Borschitz T Heintz A Junginger T 2006Dis Colon Rectum2006,49,10:1
13Transanal endoscopic microsurgical excision of pT2 rectal cancer: results and possible indications 显示文摘Borschitz T Heintz A Junginger T 2007Dis Colon Rectum2007,50,3:1
14Improvement of a clinical score for necrotizing fasciitis: 'pain out of proportion' and high CRP levels aid the diagnosis显示文摘Borschitz T Schlicht S Siegel E 2015PLoS One2015,10,01:1
15Neoadjuvant chemora-diation and local excision for T2-3 rectal cancer 显示文摘Borschitz T Wachtlin D Mohler M 2008Ann Surg0nool2008,15,3:1
16Perforation into the peritoneal cavity during transanal endoscopic microsurgery for rectal cancer is not associated with major complications or oncological compromise显示文摘Gunnar Baatrup Thomas Borschitz Christoffer Cunningham Niels Qvist 2009Surgical Endoscopy2009,,12:1
17Neoadjuvant chemoradiation and local excision for T2-3 rectal cancer显示文摘Borschitz T Wachtlin D Mohler M 0,,03:1
18Neoadjuvant chemoradiation and local excision for T2-3 rectal cancer 显示文摘Borschitz T Wachtlin D Mohler M 2008AnnSurgOncol2008,15,3:1
19Neoadjuvant chemoradiation and local excision for T2-3 rectal cancer 显示文摘Borschitz T Wachtlin D Mohler M 2008Ann Surg Oncol2008,15,:1
20The influence of histopathologic criteria on the long-term prognosis of locally excised pT1 rectal car-cinomas:results of local exci-sion(transanal endoscopicmicrosurgery)and immediate reoperation显示文摘Borschitz T Heintz A Junginger T 2006Dis Colon Rectum2006,49,10:1
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