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12篇 您的检索式：作者名="Bote G"

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		题名	作者	年代	出处	被引量
	1	The addition of HZSM-5 to the Fischer-Tropsch process for improved gasoline production显示文摘	Bhringer W	2004	Applied Catalysis A2004，267，12：	1
	2	显示文摘	Lorenzen L Van Deventer J S J	1998	Chemical Engineering Communication1998，170，：	1
	3	Genomic typing of Pseudomonas aeruginosa isolates by comparison of riboprinting and PFGE : correlation of experimental results with those predicted from the complete genome sequence of isolate PAO1 显示文摘	Botes J Williamson G Sinickas V	2003	J Microbiol Met2003，55，1：	1
	4	Rotavirus detection and characterisation in outbreaks of gastroenteritis in aged-care facilities显示文摘	Marshall J Botes J Gorrie G	2003	J Clin Virol2003，28，：	1
	5	Mechanistic pathway for C2+ hydrocarbons over an Fe/K catalyst显示文摘	Govender N S Botes F G de Croon M H J M	2014	Journal 0/ Catalysis2014，312，：	1
	6	Process parameter influence on performance of friction taper stud welds in AISI 4140 steel显示文摘	Hattingh D G Bulbring D L H Els -Botes A	2011	Materials and Design2011，32，6：	1
	7	A comparison of cobalt and iron based slurry phase Fischer-Tropsch synthesis显示文摘	BOTES F G NIEMANTSWERDRIET J W VAN DE LOOSDRECHT J	2013	Catal Today2013，215，：	1
	8	Citation flows inthe zones of influence of scientific collaborations显示文摘	Lancho Barrantes B S Bote G Vicente P	2012	Journal of theAmerican Society for Information Science and Technology2012，63，3：	1
	9	Mechanis- tic pathway for methane formation over an iron-based catalyst 显示文摘	Govender N S Botes F G Croon M H J M	2008	Journal of Catalysis2008，260，2：	1
	10	Quantifying the benefits of international scientific collaboration 显示文摘	Bote G Vicente P Olmeda-Gomez C	2013	Journal of the American Society for Information Science and Technology2013，64，2：	1
	11	Biocatalytic resolution of 1,2-epoxyoctane using resting cells of different yeast strains with novel epoxide hydrolase activities显示文摘	BOTES A L WEIJERS C A G M van DYK M S	1998	Biotechnol Lett1998，20，4：	1
	12	Layer-by-layer heparinization of decellularized liver matrices to reduce thrombogenicity of tissue engineered grafts显示文摘Background: Tissue-engineered liver grafts may offer a viable alternative to orthotopic liver transplantation and help overcome the donor organ shortage. Decellularized liver matrices (DLM) have a preserved vasculature and sustain hepatocellular function in culture, but graft survival after transplantation remains limited due to thrombogenicity of the matrix. Aim: To evaluate the effect of heparin immobilization on DLM thrombogenicity. Methods: Heparin was immobilized on DLMs by means of layer-by-layer deposition. Grafts with 4 or 8 bilayers and 2 or 4 g/L of heparin were recellularized with primary rat hepatocytes and maintained in culture for 5 days. Hemocompatibility of the graft was assessed by ex vivo diluted whole-blood perfusion and heterotopic transplantation. Results: Heparin was deposited throughout the matrix and the heparin content in the graft was higher with increasing number of bilayers and concentration of heparin. Recellularization and in vitro albumin and urea production were unaffected by heparinization. Resistance to blood flow during ex vivo perfusion was lower with increased heparinization and, macroscopically, no clots were visible in grafts with 8 bilayers. Following transplantation, flow through the graft was limited in all groups. Histological evidence of thrombosis was lower in heparinized DLMs, but transplantation of DLM grafts was not improved. Conclusions: Layer-by-layer deposition of heparin on a DLM is an effective method of immobilizing heparin throughout the graft and does not impede recellularization or hepatocellular function in vitro. Thrombogenicity during ex vivo blood perfusion was reduced in heparinized grafts and optimal with 8 bilayers, but transplantation remained unsuccessful with this method. Relevance for patients: Tissue engineered liver grafts may offer a viable solution to dramatic shortages in donor organs.	Bote G Bruinsma Yeonhee Kim Tim A Berendsen Sinan Ozer Martin L Yarmush Basak E Uygun	2015	Journal of Clinical & Translational Research2015，1，1：	0

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