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14篇 您的检索式:作者名="Bout L"
    题名 作者 年代 出处 被引量
1Sex-specific differences in white matter microvascular integrity after ischaemic stroke显示文摘background and purpose Functional outcomes after ischaemic stroke are worse in women,despite adjusting for differences in comorbidities and treatment approaches.White matter microvascular integrity represents one risk factor for poor long-term functional outcomes after ischaemic stroke.The aim of the study is to characterise sex-specific differences in microvascular integrity in individuals with acute ischaemic stroke.Methods A retrospective analysis of subjects with acute ischaemic stroke and brain MRI with diffusion-weighted(DWI)and dynamic-susceptibility contrast-enhanced(DSC)perfusion-weighted imaging obtained within 9 hours of last known well was performed.In the hemisphere contralateral to the acute infarct,normal-appearing white matter(NAWM)microvascular integrity was measured using the K_(2) coefficient and apparent diffusion coefficient(ADC)values.Regression analyses for predictors of K_(2) coefficient,DWI volume and good outcome(90-day modified Rankin scale(mRS)score<2)were performed.results 105 men and 79 women met inclusion criteria for analysis.Despite no difference in age,women had increased NAWM K_(2) coefficient(1027.4 vs 692.7×10^(-6)/s;p=0.006).In women,atrial fibrillation(β=583.6;p=0.04)and increasing NAWM ADC(β=4.4;p=0.02)were associated with increased NAWM K_(2) coefficient.In multivariable regression analysis,the K_(2) coefficient was an independent predictor of DWI volume in women(β=0.007;p=0.01)but not men.Conclusions In women with acute ischaemic stroke,increased NAWM K_(2) coefficient is associated with increased infarct volume and chronic white matter structural integrity.Prospective studies investigating sex-specific differences in white matter microvascular integrity are needed.Mark R Etherton Ona Wu Pedro Cougo Svetlana Lorenzano Hua Li Lisa Cloonan Mark J R J Bouts Arne Lauer Ken Arai Eng H Lo Steve K Feske Karen L Furie Natalia S Rost 2019Stroke & Vascular Neurology2019,4,4:2
2Quality of different chondroitin sulfate preparations in relation to their therapeutic activity显示文摘MEERW ME BOUT J V D 2009J Pharm Pharmacol2009,61,10:1
3Installing copper staves and operational practice at sidmar显示文摘Bout L DeLenghe H Depamelare M etal 1999Iron and Steel Engineer1999,,6:1
4Oeulomotor abnormalities in myoclonic tremor: a comparison with spinocerebellar ataxia type 6显示文摘Bout L J van Rootselaar AF Koelman J H 2008Brain2008,131,:1
5Development and evaluation of a guideline for nursing care of suicidal patients with schizophrenia显示文摘Meerwijk E L van Meijel B van den Bout J 2010Perspect Psychiatr Care2010,46,1:1
6Leiomyosarcoma of the bladder in a retinoblastoma patient显示文摘Bleoo S L God bout R Rayner D et a l 2003Urol Int2003,71,:1
7Installing Copper Staves and Operational Practice at Sidmar显示文摘Bout L Delenghe H Depamelare M 1999Iron and Steel Engineer1999,,6:1
8New helper cells and matched early region 1 - deleted adenovirus vectors prevent generation of replication - competent adenoviruses显示文摘Fallaux FJ Bout A Vander Velde L 1998Hum Gene Ther1998,9,13:1
9Neurophysiological aspects of eye and eyelid movements dining blinking in humans显示文摘Bout L J Aramideh M de-Visser B W 2000J Neurophysiol2000,83,1:1
10A Mobile Precursor Determines Amyloid-beta Peptide Fibril Formation at In- terfaces显示文摘Shen L Adachi T Vanden Bout D 2012J Am Chem Soc2012,134,14:1
11Installing copper staves and operational practice at sidmar显示文摘Bout L Delenghe H Depamelare M 1999Iron and Steel Engineer1999,76,6:1
12The formation of an intrachain disulfide bond in the leptin protein is necessary for efficient leptin secretion 显示文摘Boute N Ziberfarb V Camion L 2004Biochimie2004,86,:1
13Cooperative an- ion binding and electrochemical sensing bym odular podands显示文摘Abouderbala L O Be lcherW J Boute lie M G 2002Proc Natl A cad Sci USA2002,99,:1
14Internet-delivered or mailed self-help treatment for insomnia? A randomized waiting-list controlled trial显示文摘Jaap L Bout A S Victor I.S 0,,:1
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