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| 1 | Management of distal humeral coronal shear fractures显示文摘Coronal shear fractures of the distal humerus are rare,complex fractures that can be technically challenging to manage. They usually result from a low-energy fall and direct compression of the distal humerus by the radial head in a hyper-extended or semi-flexed elbow or from spontaneous reduction of a posterolateral subluxation or dislocation. Due to the small number of soft tissue attachments at this site, almost all of these fractures are displaced. The incidence of distal humeral coronal shear fractures is higher among women because of the higher rate of osteoporosis in women and the difference in carrying angle between men and women. Distal humeral coronal shear fractures may occur in isolation, may be part of a complex elbow injury, or may be associated with injuries proximal or distal to the elbow. An associated lateral collateral ligament injury is seen in up to 40% and an associated radial head fracture is seen in up to 30% of these fractures. Given the complex nature of distal humeral coronal shear fractures, there is preference for operative management. Operative fixation leads to stable anatomic reduction, restores articular congruity, and allows initiation of early range-of-motion movements in the majority of cases. Several surgical exposure and fixation techniques are available to reconstruct the articular surface fol owing distal humeral coronal shear fractures. The lateral extensile approach and fixation with countersunk headless compression screws placed in an anterior-to-posterior fashion are commonly used. We have found a two-incision approach(direct anterior and lateral) that results in less soft tissue dissection and better outcomes than the lateral extensile approach in our experience. Stiffness, pain, articular incongruity, arthritis, and ulnohumeral instability may result if reduction is non-anatomic or if fixation fails. | Shahram S Yari Nathan L Bowers Miguel A Craig Lee M Reichel | 2015 | World Journal of Clinical Cases2015，3，5： | 15 |
| 2 | Chemoprotective effects of curcumin in esophageal epithelial cells exposed to bile acids显示文摘AIM:To investigate the ability of curcumin to counteract the impact of bile acids on gene expression of esophageal epithelial cells.METHODS:An esophageal epithelial cell line(HET1A)was treated with curcumin in the presence of deoxycholic acid.Cell proliferation and viability assays were used to establish an appropriate dose range for curcumin.The combined and individual effects of curcumin and bile acid on cyclooxygenase-2(COX-2)and superoxide dismutase(SOD-1 and SOD-2)gene expression were also assessed.RESULTS:Curcumin in a dose range of 10-100μmol/L displayed minimal inhibition of HET-1A cell viability.Deoxycholic acid at a concentration of 200μmol/L caused a 2.4-fold increase in COX-2 gene expression compared to vehicle control.The increased expression of COX-2 induced by deoxycholic acid was partially reversed by the addition of curcumin,and curcumin reduced COX-2 expression 3.3-to 1.3-fold.HET-1A cells exposed to bile acid yielded reduced expression of SOD-1 and SOD-2 genes with the exception that high dose deoxycholic acid at 200μmol/L led to a 3-fold increase in SOD-2 expression.The addition of curcumin treatment partially reversed the bile acid-induced reduction in SOD-1 expression at all concentrations of curcumin tested.CONCLUSION:Curcumin reverses bile acid suppression of gene expression of SOD-1.Curcumin is also able to inhibit bile acid induction of COX-2 gene expression. | Matthew R Bower Harini S Aiyer Robert CG Martin Yan Li | 2010 | World Journal of Gastroenterology2010，16，33： | 10 |
| 3 | What is the meaning of non-line-ar dose–response relationships between blood lead concentrationsand IQ显示文摘 | Teresa S Bowers Barbara D Beck | 2006 | NeuroToxicology2006，，27： | 1 |
| 4 | Platinum silicide fusion bonding显示文摘 | ISMAIL M S BOWER R W | 1991 | Electronics Letters1991，27，13： | 1 |
| 5 | Diseases of cultured Japanese scallops (Patinopecten yessoensis ) in British Columbia, Canada 显示文摘 | Bower S M Blackbourn J Meyer G R | 1992 | Aquaculture1992，107，： | 1 |
| 6 | Calculation of the thermodynamic and geochemical consequences of non-ideal mixing in the system H2O-CO2-NaC1 on phase relations in geologic systems: Metamorphic equilibria at high pressures and temperatures 显示文摘 | Bowers T S Helgeson H C | 1983 | America Mineralogist1983，68，： | 1 |
| 7 | Aircraft route op- timization for formation flight 显示文摘 | Xu J S Ning S A Bower G C Kroo I M | 2014 | Journal of Aircraft2014，51，2： | 1 |
| 8 | Foamedasphalt Paving Mixtures:Preparation of Design Mixes and Treatment of Test Specimens显示文摘 | Ruckel PJ Acott S M Bowering R H | 1983 | Transportation Research Record1983，911，： | 1 |
| 9 | Cholesteryl ester transfer protein expression prevents dietinduced atherosclerotic lesions in male db/db mice显示文摘 | MACLEAN P S BOWER J F VADLAMUDI S | 2003 | Arterioscler Thromb Vasc Biol2003，23，8： | 1 |
| 10 | Modeling sucrose hydrolysis in dilute sulfuric acid solutions at pretreatment conditions for lignocellulosic biomass显示文摘 | Bower S Wickramasinghe R Nagle N J | 2008 | Bioresource Technology2008，99，15： | 1 |
| 11 | Acquired and innate resistance to the haemoflagellate Cryptobia salmositica in sockeye salmon (Oncorhynchus nerka) 显示文摘 | Bower S M Evelyn T P | 1988 | Dev Comp Immunol1988，12，： | 1 |
| 12 | SKIP3, a novel Drosophila tribbles ortholog, is overexpressed in human tumors and is regulated by hypoxia显示文摘 | Bowers A J Scully S Boylan JF | 2003 | Oncogene2003，22，18： | 1 |
| 13 | Costs of intravenous adverse drug events in academic and nonacademic intensive care units 显示文摘 | NUCKOLS T K PADDOCK S M BOWER A G | 2008 | Med Care2008，46，1： | 1 |
| 14 | 显示文摘 | Bower C Zhu W Jin S | 2000 | Appl Phys Lett2000，77，： | 1 |
| 15 | Two members of the thioredoxin-h family interact with the kinase domain of a Brassica S-locus receptor kinase 显示文摘 | Bower M S Matias D D Femandes-carvalho E Mazzurco M Gu T Rothstein A J and Goring D R | 1996 | Plant Cell1996，8，： | 1 |
| 16 | Neuroendocrine-immune mechanisms of behavioral comorbidities in patients with cancer显示文摘 | Miller AH Ancoli-lsrael S Bower JE | 2008 | Clin Oncol2008，26，6： | 1 |
| 17 | Exploring parameter space in detailed single neuron models: simulations of the mitral and granule cells of the olfactory bulb 显示文摘 | Bhalla U S Bower J M | 1993 | The Journal of Neuroseienee1993，69，： | 1 |
| 18 | The role of transbronchial fineneedle aspiration in an integrated care pathway for the assessment ofpatients with suspected lung cancer显示文摘 | Shah P L Singh S Bower M | 2006 | J Thorac Oncol2006，，4： | 1 |
| 19 | Global analysis of protein expression in yeast显示文摘 | Ghaemmaghami S Huh W K Bower K | 2003 | Nature2003，425，： | 1 |
| 20 | 查看详情显示文摘 | Haynam C A Wegner P J Auerbach J M Bowers M W Dixit S N Erbert G V Heestand G M Henesian M A Hermann M R Jancaitis K S Manes K R Marshall C D Mehta N C Menapace J Moses E Murray J R Nostrand M C Orth C D Patterson R SacksR A Shaw M J Spaeth M Sutton S B W | | 0，，： | 1 |
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