|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Effect of inflammatory bowel disease treatments on patients with diabetes mellitus显示文摘As medical care progresses and the number of patients with chronic conditions increases there is the inevitable challenge of managing patients with multiple comorbidities.Inflammatory bowel disease(IBD)is an umbrella term for are inflammatory conditions affecting the gastrointestinal tract,the two most common forms being Ulcerative Colitis and Crohn’s disease.These diseases,usually diagnosed in young adults,exhibit a relapsing and remitting course and usually require longterm treatment.IBD can be treated with a number of topical and systemic treatments.We conducted a review of the current published evidence for the effects these medications can have on diabetes mellitus(DM)and glycaemic control.Searches were conducted on medline and embase with a timeframe from 1947(the date from which studies on embase are recorded)to November 2020.Suitable publications were selected and reviewed.Current evidence of the impact of aminosalicylates,corticosteroids,thiopurines,and biologic agents was reviewed.Though there was limited evidence for certain agents,IBD medications have been shown to have an effect of DM and these effects should be considered in managing patients with dual pathologies.The effects of steroids on blood sugar control is well documented,but consideration of other agents is also important.In patients requiring steroids for Ulcerative Colitis,locally acting steroid agents delivered rectally may be preferred to minimise side effects in those with distal bowel Ulcerative Colitis.A switch to other agents should be considered as soon as possible in people with diabetes to limit the impact on glycaemic control.5-aminosalicylates appear to play a role in the reduction of hemoglobin A1c(HbA1c),although the literature suggests these may be falsely low readings.Consequently,monitoring of people with diabetes on these agents may require daily monitoring of capillary blood sugars rather than relying simply on HbA1c;for example fructosamine performed 3-6 monthly,although this risks missing the rise in readings.There is only limited evidence of the effects of thiopurines on diabetes and further investigation is needed into the possible relationship between them.However,given the current available evidence it may be preferable to commence patients with diabetes on thiopurines as soon as possible,whilst also monitoring for side effects such as pancreatitis.There appears to be more evidence supporting a link between tumor necrosis factor-αinhibitors and DM.Both infliximab and adalimumab have evidence suggesting that both can cause reduced blood sugar levels.Further studies on the effects of the various biological agents mentioned are required alongside any novel biologic therapy and the impact of dual biologic therapy in the future. | Joshua Ashley Jack Bower Lauren O'Flynn Rakhi Kakad David Aldulaimi | 2021 | World Journal of Diabetes2021，12，8： | 1 |
| 2 | The interlaminar tensile and shear behavior of a unidirectional C-C composite显示文摘 | Lam-Curzio Edgar Bowers David Ferber Mattison K | 1996 | Journal of Nuclear Materials1996，230，3： | 1 |
| 3 | Organizational theory and human resource accounting 显示文摘 | Likert Rensis Bowers David G | 1969 | American Psychologist1969，24，6： | 1 |
| 4 | Anton, a special-purpose machine for molecular dynamics simulation显示文摘 | David E. Shaw Martin M. Deneroff Ron O. Dror Jeffrey S. Kuskin Richard H. Larson John K. Salmon Cliff Young Brannon Batson Kevin J. Bowers Jack C. Chao Michael P. Eastwood Joseph Gagliardo J. P. Grossman C. Richard Ho Douglas J. Ierardi István Kolossváry | 2007 | ACM SIGARCH Computer Architecture News2007，，2： | 1 |
| 5 | Exudation and decomposition of chromophoric dissolved organic matter (CDOM) from some temperate macroalgae显示文摘 | Christopher J. Hulatt David N. Thomas David G. Bowers Louiza Norman Chi Zhang | 2009 | Estuarine, Coastal and Shelf Science2009，，1： | 1 |
| 6 | Differential Diagnosis of Prostatism: a 12-year Retrospective Analysis of Symptoms, Urodynamics and Satisfaction with Therapy显示文摘 | Steven A. Kaplan David L. Bowers Alexis E. Te Carl A. Olsson | 1996 | The Journal of Urology1996，，4： | 1 |
| 7 | What makes a successful volunteer Expert Patients Programme tutor? Factors predicting satisfaction, productivity and intention to continue tutoring of a new public health workforce in the United Kingdom显示文摘 | Wendy Macdonald Evangelos Kontopantelis Peter Bower Anne Kennedy Anne Rogers David Reeves | 2008 | Patient Education and Counseling2008，，1： | 1 |
| 8 | A secondary analysis of the moderating effects of depression and multimorbidity on the effectiveness of a chronic disease self-management programme显示文摘 | Mark Harrison David Reeves Elaine Harkness Jose Valderas Anne Kennedy Anne Rogers Mark Hann Peter Bower | 2011 | Patient Education and Counseling2011，，1： | 1 |
| 9 | Anton, a special-purpose machine for molecular dynamics simulation显示文摘 | David E. Shaw Martin M. Deneroff Ron O. Dror Jeffrey S. Kuskin Richard H. Larson John K. Salmon Cliff Young Brannon Batson Kevin J. Bowers Jack C. Chao Michael P. Eastwood Joseph Gagliardo J. P. Grossman C. Richard Ho Douglas J. Ierardi István Kolossváry | 2007 | ACM SIGARCH Computer Architecture News2007，，2： | 1 |
| 10 | Photodynamie therapy- induced killing is enhanced in depigmented metastatic melanoma cells显示文摘 | Sharma KV Bowers N Davids LM | 2011 | Cell Biol Int2011，35，9： | 1 |
| 11 | Suicidal Behavior, Negative Affect, Gender, and Self- Reported Delinquency in College Students 显示文摘 | Jennifer Langhinrichsen-Rohling Catalina Arata David Bowers Natalie O' Brien Allen Morgan | 2004 | Suicide & Life : Threatening Behavior2004，34，3： | 1 |
| 12 | Vena cava replacement for malignant disease: Is there a role?显示文摘 | Thomas C. Bower MD David M. Nagorney MD Barbara J. Toomey RN Peter Gloviczki MD Peter C. Pairolero MD John W. Hallett MD Kenneth J. Cherry MD | 1993 | Annals of Vascular Surgery1993，，1： | 1 |
| 13 | Simulation of networks of spiking neurons: A review of tools and strategies显示文摘 | Romain Brette Michelle Rudolph Ted Carnevale Michael Hines David Beeman James M. Bower Markus Diesmann Abigail Morrison Philip H. Goodman Frederick C. Harris Milind Zirpe Thomas Natschl?ger Dejan Pecevski Bard Ermentrout Mikael Djurfeldt Anders Lansner Ol | 2007 | Journal of Computational Neuroscience2007，，3： | 1 |
| 14 | Nature:大规模研究揭示生命所必需的基因显示文摘在哺乳动物基因组中。大约三分之一的基因是生命所必需的。在一项新的研究中,来自美国贝勒医学院等多个机构的研究人员描述了这些基因的大规模发现。以及它将如何影响对哺乳动物发育和人类疾病的理解。相关研究结果在线发表在Nature期刊上,论文标题为“High—throughput discovery of novel developmental phenotypes”。 | Dickinson, Mary E. Flenniken, Ann M. Ji, Xiao Teboul, Lydia Wong, Michael D. White, Jacqueline K. Meehan, Terrence F. Weninger, Wolfgang J. Westerberg, Henrik Adissu, Hibret Baker, Candice N. Bower, Lynette Brown, James M. Caddle, L. Brianna Chiani, Francesco Clary, Dave Cleak, James Daly, Mark J. Denegre, James M. Doe, Brendan Dolan, Mary E. Edie, Sarah M. Fuchs, Helmut Gailus-Durner, Valerie Galli, Antonella Gambadoro, Alessia Gallegos, Juan Guo, Shiying Horner, Neil R. Hsu, Chih-Wei Johnson, Sara J. Kalaga, Sowmya Keith, Lance C. Lanoue, Louise Lawson, Thomas N. Lek, Monkol Mark, Manuel Arschall, Susan M. Mason, Jeremy McElwee, Melissa L. Newbigging, Susan Nutter, Lauryl M. J. Peterson, Kevin A. Ramirez-Solis, Ramiro Rowland, Douglas J. Ryder, Edward Samocha, Kaitlin E. Seavitt, John R. Selloum, Mohammed Szoke-Kovacs, Zsombor Tamura, Masaru Trainor, Amanda G. Tudose, Ilinca Wakana, Shigeharu Warren, Jonathan Wendling, Olivia West, David B. Wong, Leeyean Yoshiki, Atsushi MacArthur, Daniel G. Tocchini-Valentini, Glauco P. Gao, Xiang Flicek, Paul Bradley, Allan Skarnes, William C. Justice, Monica J. Parkinson, Helen E. Moore, Mark Wells, Sara Braun, Robert E. Svenson, Karen L. de Angelis, Martin Hrabe Herault, Yann Mohun, Tim Mallon, Ann-Marie Henkelman, R. Mark Brown, Steve D. M. Adams, David J. Lloyd, K. C. Kent McKerlie, Colin Beaudet, Arthur L. Bucan, Maja Murray, Stephen A. | 2016 | 现代生物医学进展2016，16，31： | 1 |
| 15 | Geospatial epidemiology of leprosy in northwest Bangladesh: a 20-year retrospective observational study显示文摘Background:Leprosy is known to be unevenly distributed between and within countries.High risk areas or'hotspots'are potential targets for preventive interventions,but the underlying epidemiologic mechanisms that enable hotspots to emerge,are not yet fully understood.In this study,we identified and characterized leprosy hotspots in Bangladesh,a country with one of the highest leprosy endemicity levels globally. | Caroline A.Bulstra David J.Blok Khorshed Alam CRuth Butlin Johan Chandra Roy Bob Bowers Peter Nicholls Sake Jde Vlas Jan Hendrik Richardus | 2021 | Infectious Diseases of Poverty2021，10，2： | 1 |
| 16 | Long-term culture and passage of human fetal liver cells that synthesize albumin显示文摘 | Mary Ann Sells Jonathon Chernoff Arturo Cerda Charles Bowers David A. Shafritz Nathan Kase Judith K. Christman George Acs | 1985 | In Vitro Cellular & Developmental Biology1985，，4： | 1 |
| 17 | Randomized trial of surgical cutdown versus percutaneous access in transfemoral TAVR显示文摘 | Elizabeth M. Holper Rebeca J. Kim Michael Mack David Brown William Brinkman Morley Herbert Wells Stewart Kaitlyn Vance Bruce Bowers Todd Dewey | 2014 | Cathet Cardiovasc Intervent2014，，3： | 1 |
| 18 | 灯镜之间显示文摘镜子,我们生活中必不可少的物品之一,是自我修饰的专用工具,相信每个人的家中都会有一面镜子,或者好几面镜子,梳妆镜、穿衣镜、手境……每天早晨醒来,我们对着镜子洗漱、对着镜子整理妆容、对着镜子微笑,镜子见证了我们各种状态下的自己,它是每一位女生最真诚的"闺蜜"。每当我们使用镜子的时候,光线必须足够明亮,因为镜子需要依赖光的照耀和反射才能显现出它的魅力,而灯作为光源的一种,是家居空间中的另一种必须品, | Elkeland Jean-Baptiste Colleuille F?LSOM Studio Alain Gilles Craft Combine Yonoh Jan Plechá & Henry Wielgus BD Barcelona Design Lefteris Tsampikakis David Derksen Bower Vera&Kyte FARG & BLANCHE Moshi-mosh 李薇 范嘉苑 | 2016 | 现代装饰(家居)2016，，8： | 0 |
| 19 | Towards integrated photonic interposers for processing octave-spanning microresonator frequency combs显示文摘Microcombs-optical frequency combs generated in microresonators-have advanced tremendously in the past decade,and are advantageous for applications in frequency metrology,navigation,spectroscopy,telecommunications,and microwave photonics.Crucially,microcombs promise fully integrated miniaturized optical systems with unprecedented reductions in cost,size,weight,and power.However,the use of bulk free-space and fiber-optic comp on ents to process microcombs has restricted form factors to the table-top.Taking microcomb-based optical frequency synthesis around 1550 nm as our target application,here,we address this challenge by proposing an integrated photonics interposer architecture to replace discrete components by collecting,routing,and interfacing octave-wide microcomb-based optical signals between photonic chiplets and heterogeneously integrated devices.Experimentally,we con firm the requisite performa nee of the individual passive elements of the proposed interposer一octave-wide dichroics,multimode interferometers,and tunable ring filters,and implement the octave-spanning spectral filteri ng of a microcomb,central to the in terposer,using silicon n itride phot onics.Moreover,we show that the thick silicon nitride needed for bright dissipative Kerr soliton generation can be integrated with the comparatively thin silicon nitride interposer layer through octave-bandwidth adiabatic evanescent coupling,indicating a path towards future system-level consolidation.Fin ally,we numerically confirm the feasibility of operating the proposed in terposer synthesizer as a fully assembled system.Our interposer architecture addresses the immediate need for on-chip microcomb processing to successfully miniaturize microcomb systems and can be readily adapted to other metrology-grade applications based on optical atomic clocks and high-precision navigation and spectroscopy. | Ashutosh Rao Gregory Moille Xiyuan Lu Daron A.Westly Davide Sacchetto Michael Geiselmann Michael Zervas Scott B.Papp John Bowers Kartik Srinivasan | 2021 | Light(Science & Applications)2021，10，6： | 0 |
| 20 | 法理地震学与全面禁止核试验条约显示文摘法理地震学的用途之一就是帮助核查'全面禁止核试验条约'的执行情况。法理地震学家面临的一个重要挑战是将每年发生的成千上万次天然地震与可能违反条约的地下爆破区别开来。识别方法主要有4种:(a)体波与面波的震级比,(b)高频P波与S波能量比,(c)基于模型的方法,(d)震源深度。方法(a)和(b)有经验基础。方法(a)~(c)的不足是对全球地质学介质范围内激发的地下爆破缺少一个等效的弹性震源。可靠的常规震源深度的确定已被证明非常困难。然而,过去的十几年获得的在识别可疑震源方面的经验说明,尽管没有单一的方法能够长期奏效,但巧妙地独创性地应用各种互补方法通常能够解决可疑震源识别问题。 | David Bowers Neil D.Selby 王兴臣 郭志伟 杨婷 吴清 常莹 | 2009 | 国际地震动态2009，，10： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员