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| 1 | Endoscopic submucosal dissection for premalignant lesions and noninvasive early gastrointestinal cancers显示文摘AIM: To investigate the indication, feasibility, safety, and clinical utility of endoscopic submucosal dissection (ESD) in the management of various gastrointestinal pathologies. METHODS: The medical records of 60 consecutive patients (34 female, 26 male) who underwent ESD at the gastroenterology department of Kocaeli University from 2006-2010 were examined. Patients selected for ESDhad premalignant lesions or non-invasive early cancers of the gastrointestinal tract and had endoscopic and histological diagnoses. Early cancers were considered to be confined to the submucosa, with no lymph node involvement by means of computed tomography and endosonography. RESULTS: Sixty ESD procedures were performed. The indications were epithelial lesions (n = 39) (33/39 adenoma with high grade dysplasia, 6/39 adenoma with low grade dysplasia), neuroendocrine tumor (n = 7), cancer (n = 7) (5/7 early colorectal cancer, 2/7 early gastric cancer), granular cell tumor (n = 3), gastrointestinal stromal tumor (n = 2), and leiomyoma (n = 2). En bloc and piecemeal resection rates were 91.6% (55/60) and 8.3% (5/60), respectively. Complete and incomplete resection rates were 96.6% (58/60) and 3.3% (2/60), respectively. Complications were major bleeding [n = 3 (5%)] and perforations [n = 5 (8.3%)] (4 colon, 1 stomach). Two patients with colonic perforations and two patients with submucosal lymphatic and microvasculature invasion (1 gastric carcinoid tumor, 1 colonic adenocarcinoma) were referred to surgery. During a mean follow-up of 12 mo, 1 patient with adenoma with high grade dysplasia underwent a second ESD procedure to resect a local recurrence. CONCLUSION: ESD is a feasible and safe method for treatment of premalignant lesions and early malignant gastrointestinal epithelial and subepithelial lesions. Successful en bloc and complete resection of lesions yield high cure rates with low recurrence. | Sadettin Hulagu Omer Senturk Cem Aygun Orhan Kocaman Altay Celebi Tolga Konduk Deniz Koc Goktug Sirin Ugur Korkmaz Ali Erkan Duman Neslihan Bozkurt Gokhan Dindar Tan Attila Yesim Gurbuz Orhan TarcinDivision of Gastroenterology Derince State Hospital Kocaeli 41900 Turkey Cem Kalayci | 2011 | World Journal of Gastroenterology2011，17，13： | 23 |
| 2 | 2013 ACCF/AHA guideline a report of the American College of Cardiology Foundation/American Heart Association Task Force on Prac-rice Guidelines显示文摘 | Yancy CW Jessup M Bozkurt B for the management of heart failure | 2013 | J Am Coil Cardiol2013，62，16： | 1 |
| 3 | Treatment of vaginal agenesis with modified Abbe-Mclndoe technique:long-term follow-up in 22 patients显示文摘 | Keser A Bozkurt N Taner OF | 2005 | EarJ Obstet Gynecol Reprod Biol2005，121，1： | 1 |
| 4 | Retrograde intrarenal surgery versus percutaneous nephrolithotomy in the management of lower-pole renal stones with a diameter of 15 to 20 mm显示文摘 | Omer F Bozkurt OF Resorlu B | | 0，，07： | 1 |
| 5 | Is the percutaneous nephrolithotomy procedure complicated in patients with anterior caliceal stones显示文摘 | Tepeler A Bozkurt OF Resorlu B | 2013 | Urol Int2013，90，4： | 1 |
| 6 | Retrograde intrarenal sur- gery versus percutaneous nephrolithotomy in the management of lower - pole renal stones with a diameter of 15 to 20 mm显示文摘 | Bozkurt OF Resorlu B Yildiz Y | 2011 | J En- dourol2011，25，： | 1 |
| 7 | Retrogarde intrarenal surgery versus percutaneous nephrolithotomy in the management of lower-pole renal stones with a diameter of 15 to 20 mm显示文摘 | Bozkurt OF Resorlu B Yildiz Y | 2011 | JEndourol2011，25，25： | 1 |
| 8 | Retrograde intrarenal surgery versus percutaneous nephrolithotomy in the management of lower-pole renal stones with a diameter of 15 to 20 mm显示文摘 | BOZKURT OF REsoRLU B YILDIZ Y | 2011 | J Endourol2011，25，7： | 1 |
| 9 | Pain, wound healing and refractive comparison of mechanical and transepithelial debridement in photore- fractive keratectomy for myopia 显示文摘 | Celik U Bozkurt E Yilmaz OF | 2014 | Cont Lens Anterior Eye2014，37，6： | 1 |
| 10 | Retrograde intrarenal surgery versus percutaneous nephrolithotomy in the management of lower-pole renal stones with a diameter of 15 to 20 mm 显示文摘 | Bozkurt OF Itesorlu B Yildiz Y | 2011 | J Endourol2011，25，： | 1 |
| 11 | geotechnical engineering for transportation projects显示文摘 | GULER Erol BOZKURT Cemal E The effect of upward nail inclination to the stability of soil nailed structures | 2004 | :2213 - 22202004，，： | 1 |
| 12 | The efficacy of bupivacaine infiltration on the nephrostomy tract in tubeless and standard percutaneous nephrolithotomy: a prospective,randomized,multicenter study显示文摘 | KIRAC M TEPELER A BOZKURT OF | 2013 | Urology2013，82，3： | 1 |
| 13 | Treatment of vaginalagenesis with modified Abbe-McIndoe technique:long-term follow-up in 22 patients显示文摘 | Keser A Bozkurt N Taner OF | 2005 | Eur J Obstet GynecolReprod Biol2005，121，1： | 1 |
| 14 | The Eficacy of Bupivacaine Infiltration on the nephrostomy tract in tubeless and standard percutaneous nephrolithotomy: A prospective,randomized,multicenter study显示文摘 | MUSTAFA K ABDULKADIR T BOZKURT OF | 2013 | Urology2013，82，： | 1 |
| 15 | Retrograde intrarenal surgery versus percutaneous nephrolithotomy in the management of lower-pole renal stones with a diameter of 15 to 20 ram显示文摘 | Omer F Bozkurt OF Resorlu B | 2011 | Endourol2011，25，7： | 1 |
| 16 | Retrograde intrarenal sur- gery versus pereutaneous nephrolithotomy in the management of lower- pole renal stones with a diameter of 15 to 20 mm 显示文摘 | Bozkurt OF Resorlu B Yildiz Y | 2011 | J Endourol2011，25，7： | 1 |
| 17 | Comparing the effects of analge- sia techniques with controlled intravenous and epidural on postoper- ative pain and knee rehabilitation after total knee arthroplusty显示文摘 | Bozkurt M Yflmazlar A Bilgen OF | 2009 | Ek- lem I-Iastalik Cerrabisi2009，20，2： | 1 |
| 18 | Comparison of retrograde intrarenal surgery and mini-percutaneous nephrolithotomy in management of lower-pole renal stones with a diameter of smaller than 15 mm显示文摘 | Kirac M Bozkurt OF Tunc L | 2013 | Urolithiasis2013，41，3： | 1 |
| 19 | Retrograde intrarenal surgery versus percutaneous nephrolithotomy in the management of lower-pole renal stones with a diameter of 15 to 20 mm显示文摘 | BOZKURT OF RESORLU B YILDIZ Y | 2011 | J Endourol2011，25，7： | 1 |
| 20 | Retrograde intrarenal surgery versus percutaneous nephrolithotomy in the management of lower- pole renal stones with a diameter of 15 to 20 mm显示文摘 | Bozkurt OF Resorlu B Yildiz Y | 2011 | J Endourol2011，25，7： | 1 |
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