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67篇 您的检索式：作者名="Brachman"

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	题名	作者	年代	出处	被引量
1	RTOG 0211:a phase 1/2 study of radiation therapy with concurrent gefitinib for newly diagnosed glioblastoma patients显示文摘PURPOSE: To determine the safety and efficacy of gefitinib,an epidermal growth factor receptor(EGFR) tyrosine kinase inhibitor,in combination with radiation for newly diagnosed glioblastoma(GBM) patients.METHODS AND MATERIALS: Between March 21,2002,and May 3,2004,Radiation Therapy Oncology Group(RTOG) 0211 enrolled 31 and 147GBM patients in the phase 1 and 2 arms,respectively.Treatment consisted of daily oral gefinitnib started at the time of conventional cranial radiation therapy(RT) and continued post RT for 18 months or until progression.Tissue microarrays from 68 cases were analyzed for EGFR expression.RESULTS: The maximum tolerated dose(MTD) of gefitinib was determined to be 500 mg in patients on non-enzyme-inducing anticonvulsant drugs(non-EIAEDs).All patients in the phase 2 component were treated at a gefitinib dose of 500 mg;patients receiving EIADSs could be escalated to 750 mg.The most common side effects of gefitinib in combination with radiation were dermatologic and gastrointestinal.Median survival was 11.5 months for patients treated per protocol.There was no overall survival benefit for patients treated with gefitinib + RT when compared with a historical cohort of patients treated with RT alone,matched by RTOG recursive partitioning analysis(RPA) class distribution.Younger age was significantly associated with better outcome.Per protocol stratification,EGFR expression was not found to be of prognostic value for gefitinib + RT-treated patients.CONCLUSIONS: The addition of gefitinib to RT is well tolerated.Median survival of RTOG 0211 patients treated with RT with concurrent and adjuvant gefitinib was similar to that in a historical control cohort treated with radiation alone.	Chakravarti A Wang M Robins HI Lautenschlaeger T Curran WJ Brachman DG Schultz CJ Choucair A Dolled-Filhart M Christiansen J Gustavson M Molinaro A Mischel P Dicker AP Bredel M Mehta M	2013	中国神经肿瘤杂志2013，11，1：	8
2	Salmonellosis in the United States-a five-year review显示文摘	Aserkoff B Schroeder S A Brachman P S	1970	Am J Epidemiology1970，92，1：	1
3	Randomized compar- ison of stereotactic radiosurgery followed by conventional radiothera- py with earmustine to conventional radiotherapy with carmustine for patients with glioblastoma muhiforme: report of Radiation Therapy Oncology Group 93 - 05 protocol 显示文摘	Souhami L Seiferheld W Brachman D	2004	Int J Radiat Oncol Biol Phys2004，60，3：	1
4	What IS-A is and isn′t:An analysis of taxonomic links in semantic networks显示文摘	Brachman R	1983	Computer1983，16，10：	1
5	Glucocorticoids orchestrate divergent effects on mood through adult neurogenesis 显示文摘	Lehmann ML Brachman RA Martinowich K	2013	J Neurosci2013，33，7：	1
6	Randomized comparison of stereotactic radiosurgery followed by conventional radiotherapy with carmustine to conventional radiotherapy with carmustine for patients with glioblastoma multiforme:report of Radiation Therapy Oncology Group 93-05 protocol显示文摘	Souhami L Seiferheld W Brachman D	2004	Int J Radiat Oncol Biol Phys2004，60，3：	1
7	Deformations of a geosythetic clay liner beneath a geomembrane wrinkle and coarse gravel显示文摘	Dickinson S Brachman R W I	2006	Geotextiles and Geomembranes2006，24，：	1
8	Invasiv Haemophilus influenzae disease inadults a prospectiv popu-lationbased surveiuance显示文摘	Farley MM Stephens DS Brachman PS	1992	Ann Intern Med1992，11，10：	1
9	Estimating liquefaction-induced ground settlements from CPT for level ground显示文摘	ZHANG G ROBERTSON P K BRACHMAN R W I	2002	Canadian Geotechnical Journal2002，39，5：	1
10	An overview of the KL-ONE knowl-edge representation system显示文摘	Brachman R J Sehmolze J G		0，，02：	1
11	Standard sampler for assay of airborne microorganisms显示文摘	BRACHMAN P S EHRLICH R EICHENWALD H F	1964	Science1964，144，：	1
12	Deformations of a geosynthetic clay liner beneath a geomembrane wrinkle and coarse gravel显示文摘	DICKINSON S BRACHMAN R W I	2006	Geotextiles and Geomembranes2006，24，：	1
13	Randomized comparison of stereotactic radiosurgery followed by conventional radiotherapy with carmustine to conventional radiotherapy with cammstine tor patients with glioblastoma multiforage : report of radiation therapy oncology group 93-05 protocol 显示文摘	Souhami L Seiferheld W Brachman D	2004	Int J Radiat Oncol Biol Phys2004，60，：	1
14	Failure-free survival following brachytherapy alone or external beam irradiation alone for T1-2 prostate tumors in 2222 patients: results from a single practice显示文摘	Brachman DG Thomas T Hilbe J	2000	Int J Radiat Oncol Biol Phys2000，48，1：	1
15	Sensitivity of auditory-nerve fibers to changes in intensity:a dichotomy between decrements and increments显示文摘	Smith RL Brachman ML Frisina RD		0，，：	1
16	Operating range and maximum response of single auditory nerve fibers显示文摘	Smith RL Brachman ML		0，，：	1
17	The impact of adjuvant stereotactic radiosurgery on atypical meningioma recurrence follow- ing aggressive microsurgical resection 显示文摘	Hardesty DA Wolf AB Brachman DG	2013	J Neurosurg2013，119，：	1
18	The impact of adju- vant stereotactic radiosurgery on atypical meningioma recurrence following aggressive microsurgical resection 显示文摘	Hardesty DA Wolf AB Brachman DG	2013	J Neurosurg2013，119，：	1
19	Grout field trials in outwash sands显示文摘	Brachman R W I Martin C D Gilliss S A	2004	Canadian Geoteehnical Journal2004，41，：	1
20	Estimating liquefaction-induced lateral displacements using the standard penetration test or cone penetration test显示文摘	Zhang G Robertson P K Brachman R W I	2004	Journal of Geoteehnical and Geeenvironmental Engineering2004，130，8：	1

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