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| 1 | Adulteration of diesel/biodiesel blends by vegetable oil as determined by Fourier transform (FT) near infrared spectrometry and FT-Raman spectroscopy显示文摘 | Flavia C.C. Oliveira Christian R.R. Brand?o Hugo F. Ramalho Leonardo A.F. da Costa Paulo A.Z. Suarez Joel C. Rubim | 2007 | Analytica Chimica Acta2007，，2： | 1 |
| 2 | Resection arthroplasty of the hip显示文摘 | Lowry DA Brand RA | 1995 | J Arthroplasty1995，10，： | 1 |
| 3 | Sustained hyperinsulinemia increases arterial pressure in conscious rats显示文摘 | Brands MW Hildebrandt DA Mizelle HL | 1991 | Am J Physiol1991，260，4： | 1 |
| 4 | Uncoupling protein 3 protects aconitase against inactivation in isolated skeletal muscle mitochondria显示文摘 | Talbot DA Brand MD | 2005 | Biochim Biophys Acta2005，1709，2： | 1 |
| 5 | Co-nanoencapsulated meloxicam and curcumin improves cognitive impairment induced by amyloid-beta through modulation of cyclooxygenase-2 in mice显示文摘Alzheimer’s disease is a progressive brain disorder and complex mechanisms are involved in the physiopathology of Alzheimer’s disease.However,there is data suggesting that inflammation plays a role in its development and progression.Indeed,some non-steroidal antiinflammatory drugs,such as meloxicam,which act by inhibiting cyclooxygenase-2 have been used as neuroprotective agents in different neurodegenerative disease models.The purpose of this study was to investigate the effects of co-nanoencapsulated curcumin and meloxicam in lipid core nanocapsules(LCN)on cognitive impairment induced by amyloid-beta peptide injection in mice.LCN were prepared by the nanoprecipitation method.Male Swiss mice received a single intracerebroventricular injection of amyloid-beta peptide aggregates(fragment 25–35,3 nmol/3μL)or vehicle and were subsequently treated with curcumin-loaded LCN(10 mg/kg)or meloxicam-loaded LCN(5 mg/kg)or meloxicam+curcumin-co-loaded LCN(5 and 10 mg/kg,respectively).Treatments were given on alternate days for 12 days(i.e.,six doses,once every 48 hours,by intragastric gavage).Our data showed that amyloid-beta peptide infusion caused long-term memory deficits in the inhibitory avoidance and object recognition tests in mice.In the inhibitory avoidance test,both meloxicam and curcumin formulations(oil or co-loaded LCN)improved amyloid-beta-induced memory impairment in mice.However,only meloxicam and curcumin-co-loaded LCN attenuated non-aversive memory impairment in the object recognition test.Moreover,the beneficial effects of meloxicam and curcuminco-loaded LCN could be explained by the anti-inflammatory properties of these drugs through cortical cyclooxygenase-2 downregulation.Our study suggests that the neuroprotective potential of meloxicam and curcumin co-nanoencapsulation is associated with cortical cyclooxygenase-2 modulation.This study was approved by the Committee on Care and Use of Experimental Animal Resources,the Federal University of Pampa,Brazil(approval No.02-2015)on April 16,2015. | Maria Eduarda Ziani Gutierrez Anne Suély Pinto Savall Edina da Luz Abreu Kelly Ayumi Nakama Renata Bem Dos Santos Marina Costa Monteiro Guedes Daiana SilvaÁvila Cristiane Luchese Sandra Elisa Haas Caroline Brandão Quines Simone Pinton | 2021 | Neural Regeneration Research2021，16，4： | 1 |
| 6 | Inhaling to mitigate exhaled bioaerosols 显示文摘 | Edwards DA Man JC Brand P | 2004 | PNAS2004，101，17： | 1 |
| 7 | Adequacy of antiteta- nus prophylaxis in six hospital emergency rooms显示文摘 | Brand DA Acampora D Gottlieb LD | 1983 | N Enql J Med:1983，309，11： | 1 |
| 8 | DNA methylation of T(H)I/T(H)2 cytokine genes affects sensitization and progress of experimental asthma显示文摘 | Brand S Kesper DA Teich RA | 2012 | J Allergy Clin Immunol2012，129，6： | 1 |
| 9 | Evaluation and determination of chloride in crude oil based on the counterions Na, Ca, Mg, Sr and Fe, quantified via ICP-OES in the crude oil aqueous extract显示文摘 | Murilo de Oliveira Souza Maria Aparecida Ribeiro Maria Tereza Weitzel Dias Carneiro Geisamanda Pedrini Brand?o Athayde Eustáquio Vinícius Ribeiro de Castro Francisco Luan Fonseca da Silva Wladiana Oliveira Matos Rafael de Queiroz Ferreira | 2015 | Fuel2015，，： | 1 |
| 10 | DNA methylationof TH1/TH2 cytokine genes affects sensitization and prog- ress of experimental asthma显示文摘 | Brand S Kesper DA Teich R | 2012 | J Allergy Clin lmmunol2012，129，6： | 1 |
| 11 | 显示文摘 | Hall JE Brands MW Hildebrandt DA | 2000 | Braz J Med Biol Res2000，33，6： | 1 |
| 12 | Childhood obesity: do parents recognize this health risk? 显示文摘 | Etelson D Brand DA Patrick PA | 2003 | Obes Res2003，11，11： | 1 |
| 13 | Classifying asthma:disagreement among specialists显示文摘 | Baker KM Brand DA Hen J Jr | 2003 | Chest2003，124，： | 1 |
| 14 | Vitamin D and retinopathy in adults with diabetes mellitus 显示文摘 | Patrick PA Visintainer PF Shi Q Weiss IA Brand DA | 2012 | Arch Ophthalmol2012，130，6： | 1 |
| 15 | Long-term flue gas exposure effects of silica membranes on porous steel substrate显示文摘 | BRANDS K UHLMANN D SMART S BRAM M DIN/Z DA COSTA J C | 2010 | J Membr Sci2010，359，1： | 1 |
| 16 | The GAlA system: a versatile system for the expression of genes显示文摘 | Elliott DA Brand AH | 2008 | Methods Mol Biol2008，420，： | 1 |
| 17 | Impact of Rapid Weight Reduction on Risk of Cholelithiasis after Bariatric Surgery显示文摘 | Carlos Iglézias Brand?o de Oliveira MD Elinton Adami Chaim PhD MD Benedito Borges da Silva PhD MD | 2003 | Obesity Surgery2003，，4： | 1 |
| 18 | Box-Behnken design:an alternative for the optimization of analytical methods显示文摘 | Ferreira S L C Bruns R E Ferreira H S Matos G D David J M Brand(a)o G C da Silva E G P Portugal L A dos Reis P S Souza A S dos Santos W N L | | 0，，02： | 1 |
| 19 | A computer protocol to predict myocardial infarction in emergency department patients with chest pain显示文摘 | Goldman L Cook EF Brand DA | 1988 | N Eng J Med1988，318，5： | 1 |
| 20 | Classifying asthma: disagreement among specialists显示文摘 | Baker KM Brand DA Hen J Jr | 2003 | Chest2003，124，6： | 1 |
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