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| 1 | Primary prophylaxis of variceal bleeding in patients with cirrhosis:A comparison of different strategies显示文摘Patients with cirrhosis and esophageal varices bleed at a yearly rate of 5%-15%,and,when variceal hemorrhage develops,mortality reaches 20%.Patients are deemed at high risk of bleeding when they present with medium or large-sized varices,when they have red signs on varices of any size and when they are classified as Child-Pugh C and have varices of any size.In order to avoid variceal bleeding and death,individuals with cirrhosis at high risk of bleeding must undergo primary prophylaxis,for which currently recommended strategies are the use of traditional non-selective beta-blockers(NSBBs)(i.e.,propranolol or nadolol),carvedilol(a NSBB with additional alpha-adrenergic blocking effect)or endoscopic variceal ligation(EVL).The superiority of one of these alternatives over the others is controversial.While EVL might be superior to pharmacological therapy regarding the prevention of the first bleeding episode,either traditional NSBBs or carvedilol seem to play a more prominent role in mortality reduction,probably due to their capacity of preventing other complications of cirrhosis through the decrease in portal hypertension.A sequential strategy,in which patients unresponsive to pharmacological therapy would be submitted to endoscopic treatment,or the combination of pharmacological and endoscopic strategies might be beneficial and deserve further investigation. | Ângelo Zambam de Mattos Carlos Terra Alberto Queiroz Farias Paulo Lisboa Bittencourt Alliance of Brazilian Centers for Cirrhosis Care–the ABC Group | 2021 | World Journal of Gastrointestinal Endoscopy2021，13，12： | 8 |
| 2 | End result of a prospective trial on elective lateral neck dissection vs type Ⅲ modified radical neck dissection in the management of supraglottic and transglottic carcinomas显示文摘 | Brazilian Head and Neck Cancer Study Group | 1999 | Head Neck1999，21，5： | 1 |
| 3 | Results of a prospective trial on elective modified radical classical versus supraomohyoid neck dissection in the management of oral squamous carcinoma显示文摘 | Brazilian Head and Neck Cancer Study Group | 1998 | Am J Surg1998，176，5： | 1 |
| 4 | One-year follow-up of a Brazilian randomized multicenter study comparing tacrolimus versus cyclosporine in kidney transplantation显示文摘 | Campos HH Abbud Filho M Brazilian Tacrolimus Study Group | 2002 | Transplant Proc2002，34，5： | 1 |
| 5 | End results of a prospective trial on elective lateral neck dissection vs type m modified radical neck dissection in the management of supraglottic and transglottic carcinomas 显示文摘 | Brazilian Head and Neck Cancer Study Group | 1999 | Head Neck1999，21，： | 1 |
| 6 | Results of a prospective trial on elective modified radical classical versus supraomohyoid neck dissection in the manaement of oral squamous carcinoma显示文摘 | | 1998 | Am J Srug1998，176，4： | 1 |
| 7 | Collabora- tive Study Group of infant acute ,high birth weight as an important risk factor for infant leukemia 显示文摘 | Koifman S Pombo-de-Oliveira MS Brazilian L | 2008 | Br J Cancer2008，98，3： | 1 |
| 8 | Results of a prospective trial on elective modified radical classical versus supraomohyoid neck dissection in the management of oral squamous carcinoma显示文摘 | | 1998 | Am J Surg1998，176，5： | 1 |
| 9 | The complete genome se- quence of Chromobacterium violaceum reveals remarkable and exploitable bacterial adaptability显示文摘 | I Brazilian National Genome Project Consortium | 2003 | PNAS2003，100，11： | 1 |
| 10 | End results of a prospective trial on elective lateral neck dissection vs type Ⅲ modified radical neck dissection in the management of supraglottic and transglottic carcinomas显示文摘 | Brazilian Head and Neck Cancer Study Group | 1999 | Head Neck1999，21，8： | 1 |
| 11 | Results of a prospective trial on elective modified radical classical versus supraomohyoid neck dissection in the management of oral squamous carcinoma显示文摘 | Brazilian Head Neck Cancer Study Group | 1998 | Am J Surg1998，176，5： | 1 |
| 12 | End results of a prospective trial on elective lateral neck dissection vs type Ⅲ modified radical neck dissection in the management of supraglottic and transglottic carcinoma显示文摘 | Brazilian Head | | 0，，： | 1 |
| 13 | The completegenome sequence of Chromobacterium violaceum reveals re-markable and exploitable bacterial adaptability 显示文摘 | Brazilian National Genome Project Consortium | 2003 | Proc NatlAcad Sci USA2003，100，20： | 1 |
| 14 | Epidemiology of candidemia in Brazil:a nationwide sentinel surveillance of candidemia in eleven medical centers显示文摘 | Colombo AL Nucci M Park BJ Nouér SA ArthingtonSkaggs B da Matta DA Warnock D Morgan J Brazilian Network Candidemia Study | 2006 | J Clin Microbiol2006，44，8： | 1 |
| 15 | Results of a prospective trial on elective modified radical classical versus supraomohyoid neck dissection in the management of oral squamous carcinoma显示文摘 | Brazilian Head and Neck Cancer Study Group | 1998 | Am J Surg1998，176，5： | 1 |
| 16 | comparison between immunochemiluminescent Southern blot and nested PCR显示文摘 | Dania M A C Edison L Molecular characterization of Brazilian avian pneumovirus isolates | | 0，，： | 1 |
| 17 | T-cell lymphoblastic leukemia in early childhood presents NOTCH1 mutations and MLL rearrangements显示文摘 | Mansur M B Emerenciano M Splendore A Brewer L Hassan R Pombo-de-Oliveira M S: Brazilian Collaborative Study Group of Infant Acute Leukemia | 2010 | Leuk Res2010，34，： | 1 |
| 18 | 1 open reading frame 显示文摘 | Lunardi M Caus M P Alfieri A A Phylogenetic po- sitlon of an uneharacterized Brazilian strain of bovine pap illomavirus in the genus Xipapillomavirus based on sequen- cing of the 1 | 2010 | Genet Mol Biol2010，33，4： | 1 |
| 19 | Albumin administration in patients with cirrhosis: Current role and novel perspectives显示文摘Mortality in cirrhosis is mostly associated with the development of clinical decompensation,characterized by ascites,hepatic encephalopathy,variceal bleeding,or jaundice.Therefore,it is important to prevent and manage such complications.Traditionally,the pathophysiology of decompensated cirrhosis was explained by the peripheral arterial vasodilation hypothesis,but it is currently understood that decompensation might also be driven by a systemic inflammatory state(the systemic inflammation hypothesis).Considering its oncotic and nononcotic properties,albumin has been thoroughly evaluated in the prevention and management of several of these decompensating events.There are formal evidence-based recommendations from international medical societies proposing that albumin be administered in individuals with cirrhosis undergoing large-volume paracentesis,patients with spontaneous bacterial peritonitis,those with acute kidney injury(even before the etiological diagnosis),and those with hepatorenal syndrome.Moreover,there are a few randomized controlled trials and meta-analyses suggesting a possible role for albumin infusion in patients with cirrhosis and ascites(long-term albumin administration),individuals with hepatic encephalopathy,and those with acute-on-chronic liver failure undergoing modest-volume paracentesis.Further studies are necessary to elucidate whether albumin administration also benefits patients with cirrhosis and other complications,such as individuals with extraperitoneal infections,those hospitalized with decompensated cirrhosis and hypoalbuminemia,and patients with hyponatremia. | Angelo Zambam de Mattos Douglas Alano Simonetto Carlos Terra Alberto Queiroz Farias Paulo Lisboa Bittencourt Tales Henrique Soares Pase Marlon Rubini Toazza Angelo Alves de Mattos Alliance of Brazilian Centers for Cirrhosis Care-the ABC Group | 2022 | World Journal of Gastroenterology2022，28，33： | 0 |
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