3篇
您的检索式：作者名="Brian Marples"
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| 1 | Low-dose hypersensitivity: current status and possible mechanisms显示文摘 | Michael C Joiner PHD Brian Marples PHD | 2001 | Int J Radiation Oncology Biol Phys2001，49，2： | 1 |
| 2 | Cranial irradiation significantly reduces beta amyloid plaques in the brain and improves cognition in a murine model of Alzheimer’s Disease (AD)显示文摘 | Brian Marples Mackenzie McGee Sean Callan Scott E. Bowen Bryan J. Thibodeau Daniel B. Michael George D. Wilson Michael E. Maddens James Fontanesi Alvaro A. Martinez | 2016 | Radiotherapy and Oncology2016，，： | 1 |
| 3 | Sphingomyelin phosphodiesterase acid like 3B(SMPDL3b)regulates Perilipin5(PLIN5)expression and mediates lipid droplet formation显示文摘Lipid droplets(LDs)are lipid storage organelles with a central hydrophobic core of neutral lipids that is enclosed in a monolayer of phospholipids.Though the storage of lipids,mainly cholesterol and triglycerides,was thought to be the primary function of LDs,studies have shown that they have important functions in maintaining lipid homeostasis and modulating various signaling pathways.Abnormal lipid accumulation has been recognized as a key feature in several human diseases such as obesity,diabetes,cancer,neurological diseases,cardiovascular diseases,insulin resistance,liver diseases and kidney diseases.LDs play an important role in innate immunity,in the fight against infections,and in the replication of SARS-CoV-2.Hence a tight regulation of LD metabolism is essential for proper functioning of a cell. | Shamroop Kumar Mallela Mengyuan Ge Judith Molina Javier Varona Santos Jin-Ju Kim Alla Mitrofanova Hassan Al-Ali Brian Marples Sandra Merscher Alessia Fornoni | 2022 | Genes & Diseases2022，9，6： | 0 |
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