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| 1 | Single vs dual(en bloc) kidney transplants from donors ≤ 5 years of age: A single center experience显示文摘AIM: To compare outcomes between single and dual en bloc(EB) kidney transplants(KT) from small pediatric donors. METHODS: Monocentric nonprospective review of KTs from pediatric donors ≤ 5 years of age. Dual EB KT was defined as keeping both donor kidneys attached tothe inferior vena cava and aorta, which were then used as venous and arterial conduits for the subsequent transplant into a single recipient. Donor age was less useful than either donor weight or kidney size in decision-making for kidney utilization as kidneys from donors < 8 kg or kidneys < 6 cm in length were not transplanted. Post-transplant management strategies were standardized in all patients.RESULTS: From 2002-2015, 59 KTs were performed including 34 dual EB and 25 single KTs. Mean age of donors(17 mo vs 38 mo, P < 0.001), mean weight(11.0 kg vs 17.4 kg, P = 0.046) and male donors(50% vs 84%, P = 0.01) were lower in the dual EB compared to the single KT group, respectively. Mean cold ischemia time(21 h), kidney donor profile index(KDPI; 73% vs 62%) and levels of serum creatinine(SCr, 0.37 mg/d L vs 0.49 mg/d L, all P = NS) were comparable in the dual EB and single KT groups, respectively. Actuarial graft and patient survival rates at 5-years follow-up were comparable. There was one case of thrombosis resulting in graft loss in each group. Delayed graft function incidence(12% dual EB vs 20% single KT, P = NS) was slightly lower in dual EB KT recipients. Initial duration of hospital stay(mean 5.4 d vs 5.6 d) and the one-year incidences of acute rejection(6% vs 16%), operative complications(3% vs 4%), and major infection were comparable in the dual EB and single KT groups, respectively(all P = NS). Mean 12 mo SCr and abbreviated MDRD levels were 1.17 mg/d L vs 1.35 mg/d L and 72.5 m L/min per 1.73 m^2 vs 60.5 m L/min per 1.73 m^2(both P = NS) in the dual EB and single KT groups, respectively. CONCLUSION: By transplanting kidneys from young pediatric donors into adult recipients, one can effectively expand the limited donor pool and achieve excellent medium-term outcomes. | Yousef Al-Shraideh Umar Farooq Hany El-Hennawy Alan C Farney Amudha Palanisamy Jeffrey Rogers Giuseppe Orlando Muhammad Khan Amber Reeves-Daniel William Doares Scott Kaczmorski Michael D Gautreaux Samy S Iskandar Gloria Hairston Elizabeth Brim Margaret Mangus Robert J Stratta | 2016 | World Journal of Transplantation2016，6，1： | 3 |
| 2 | Inheritance resistance of soybean to the Heterodera glycines显示文摘 | Caldwell B E C A Brim | 1960 | Agronomy Journal1960，52，： | 1 |
| 3 | An in vitro evaluation ofthe effectiveness of endotracheal suction catheters显示文摘 | Shah S Fung K Brim S | 2005 | Chest2005，128，5： | 1 |
| 4 | Outcomes and complications fol- lowing medical thoracoscopy显示文摘 | Brims FJ Arif M Chauhan AJ | 2012 | Clin Respir J2012，6，： | 1 |
| 5 | Deinococcns radiodnrans engineered for complete toluene degradation facilitates Cr(Ⅵ) reduction显示文摘 | Brim H Osborne J P Kostandarithes H M | 2006 | Microbiology2006，152，8： | 1 |
| 6 | Component-interaction au-tomata as a verification-oriented component-based system specification显示文摘 | Brim L Cerna I Varekova P | 2006 | ACM SIGSOFT Software Engineering Notes2006，31，2： | 1 |
| 7 | The Challenge of Harvesting Green Cane显示文摘 | Schem briM Carson C A | 1997 | International Cane Energy News1997，，7： | 1 |
| 8 | Distinct high - profile meth- ylated genes in eoloreetaleancer 显示文摘 | Mokarram P Kumar K Brim H | 2009 | PLoS One2009，4，9： | 1 |
| 9 | Inheritance of quantitative characters in soybean显示文摘 | Brim C A Cockerham C C | 1961 | Crop Science1961，，1： | 1 |
| 10 | Inheritance of quantitative characters in soybeans 显示文摘 | Brim C A Cockerham C C | 1961 | Crop Science1961，1，： | 1 |
| 11 | Out-of-hemodi- alysis- unit blood pressure is a superior determinant of left ventricular hypertrophy 显示文摘 | Agarwal R Brim NJ Mahenthiran J et ai | 2006 | Hypertension2006，47，1： | 1 |
| 12 | Progress in the selection for altered fatty acid composition in soybean 显示文摘 | Richard F Wilson Burton J W Brim C A | 1981 | Crop Science1981，21，： | 1 |
| 13 | Impact of BRAF, MLH1 on the incidence of microsatellite instabilily high colorectal cancer in populations based study显示文摘 | Brim H Mokarram P Naghibalhossaini F | 2008 | Mol cancer2008，7，： | 1 |
| 14 | An invitro evaluation of the effectiveness of endotracheal suction catheters显示文摘 | Shah S Fung K Brim S | 2005 | Chest2005，128，5： | 1 |
| 15 | Distinct high-profile methylated genes in colorectal cancer显示文摘 | Mokarram P Kumar K Brim H | 2009 | PLoS One2009，4，9： | 1 |
| 16 | Distinct high- profile methylated genes in colorectal cancer显示文摘 | Mokarram P Kumar K Brim H | 2009 | PLoS One2009，114，9： | 1 |
| 17 | An in vitro evaluation of the effectiveness of endotracheal suction catheters显示文摘 | Shah S Fung K Brim S | 2005 | Chest2005，128，5： | 1 |
| 18 | Engineering Deinococcus radiodurans for metal remediation in radioactive mixed waste environments显示文摘 | Brim H MeFarlan S C | | 0，，01： | 1 |
| 19 | From distributed memory cycle detection to parallel LTL model checking显示文摘 | Barnat J Brim L Chaloupka J | 2005 | ENTCS2005，3，1： | 1 |
| 20 | Designing fast LTL model checking algorithms for many-core GPUs显示文摘 | BAMAT J BAUCH P BRIM L | 2012 | Journal of Parallel and Distributed Computing2012，72，9： | 1 |
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