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| 1 | Relationship between Th17 immune response and cancer显示文摘Cancer is the second leading cause of death worldwide and epidemiological projections predict growing cancer mortality rates in the next decades.Cancer has a close relationship with the immune system and,although Th17 cells are known to play roles in the immune response against microorganisms and in autoimmunity,studies have emphasized their roles in cancer pathogenesis.The Th17 immune response profile is involved in several types of cancer including urogenital,respiratory,gastrointestinal,and skin cancers.This type of immune response exerts pro and antitumor functions through several mechanisms,depending on the context of each tumor,including the protumor angiogenesis and exhaustion of T cells and the antitumor recruitment of T cells and neutrophils to the tumor microenvironment.Among other factors,the paradoxical behavior of Th17 cells in this setting has been attributed to its plasticity potential,which makes possible their conversion into other types of T cells such as Th17/Treg and Th17/Th1 cells.Interleukin(IL)-17 stands out among Th17-related cytokines since it modulates pathways and interacts with other cell profiles in the tumor microenvironment,which allow Th17 cells to prevail in tumors.Moreover,the IL-17 is able to mediate pro and antitumor processes that influence the development and progression of various cancers,being associated with variable clinical outcomes.The understanding of the relationship between the Th17 immune response and cancer as well as the singularities of carcinogenic processes in each type of tumor is crucial for the identification of new therapeutic targets. | Hanna Santos Marques Breno Bittencourt de Brito Filipe Antônio França da Silva Maria Luísa Cordeiro Santos Júlio César Braga de Souza Thiago Macêdo Lopes Correia Luana Weber Lopes Nayara Silva de Macêdo Neres Rafael Santos Dantas Miranda Dórea Anna Carolina Saúde Dantas Lorena Lôbo Brito Morbeck Iasmin Souza Lima Amanda Alves de Almeida Maiara Raulina de Jesus Dias Fabrício Freire de Melo | 2021 | World Journal of Clinical Oncology2021，12，10： | 5 |
| 2 | Adenosine receptors: expression, function and regulation 显示文摘 | Sheth S Brito R Mukherjea D | 2014 | Int J Mol Sci2014，15，2： | 1 |
| 3 | Effects of the Mi 1, N and tabasco genes on infection and reproduction of Meloidogyne mayaguensis on tomato and pepper genotypes 显示文摘 | Brito J A Stanley J D Kaur R | 2007 | Journal of Nematology2007，39，4： | 1 |
| 4 | Bacteriocin production by Lactobacillus pentosus B96 can be expressed as a function of temperature and NaC1 concentration显示文摘 | DELGADO A BRITO D PERES C | 2005 | Food Microbiology2005，22，6： | 1 |
| 5 | Descriptive study on pulmonary embolism in an urban-teaching hospital 显示文摘 | SCHWED D MURALI G BRITO C | 2006 | Chest2006，130，： | 1 |
| 6 | Ultrasonic Doppler Velocimetry in Liquid Gallium 显示文摘 | Brito D Natal H C Cardin P | 2001 | Experiments in Fluids2001，31，6： | 1 |
| 7 | Aerodynamic instability of cylindrical bluff bodies in non-bomogennous flow 显示文摘 | Brito J L V Rjera J D | 1995 | J of WEIA1995，57，： | 1 |
| 8 | Neurovaseular unit: afo- eus on perieytes显示文摘 | Sa-Pereira I Brites D Brito MA | 2012 | Mol Neurobiol2012，45，2： | 1 |
| 9 | Community genomics among stratified microbial assemblages in the ocean's interior显示文摘 | DeLong E F Preston C M Mincer T Rich V Hallam S J Frigaard N U Martinez A Sullivan M B Edwards R Brito B R Chisholm S W Karl D M | | 0，，5760： | 1 |
| 10 | Bilirubin toxicity to human erythrocytes: A review显示文摘 | Brito MA Silva RF Brites D | 2006 | Clin Chim Acta2006，374，12： | 1 |
| 11 | Mechanical behaviour of concrete made with fine recycled concrete aggregates 显示文摘 | Evangelista L Brito J D | 2007 | Cement and Concrete Composites2007，29，5： | 1 |
| 12 | TRPV1 : a potential drug target for treating various diseases 显示文摘 | Brito R Sheth S Mukherjea D | 2014 | Cells2014，3，2： | 1 |
| 13 | Fault detection and classification in transmission lines based on wavelet transform and ANN显示文摘 | Silva K M Souza B A Brito N S D | 2006 | IEEE Transactions onPowerDelivery2006，21，4： | 1 |
| 14 | Effect of compost on rhizosphere microflora of the tomato and on the incidence of plant growth-promoting rhizobacteria显示文摘 | Brito D E Marcos A Alvare Z | 1995 | Applied and Environmental Microbiology1995，61，1： | 1 |
| 15 | Nitrogen transport in plants,with emphasis on the regulation of fluxes to match plant demand显示文摘 | Glass A D M Brito D T Kaiser B | 2001 | J Plant Nutr Soil Sci2001，164，： | 1 |
| 16 | The regulation of nitrate and ammonium transport systems in plants显示文摘 | Glass A D M Brito D T Kaiser B N | 2002 | Journal of Experimental Botany2002，53，370： | 1 |
| 17 | Effects of environmental factors, age and genotype on sperm production and semen quality in Bos indicus and Bos taurus AI bulls in Brazil显示文摘 | Brito L F C Silva A E D F Rodrigues L H | 2002 | Anita Reprod Sci2002，70，： | 1 |
| 18 | Preemptive mergers under spatial competition 显示文摘 | Brito D | 2003 | International Journal of Industrial Organization2003，21，10： | 1 |
| 19 | Transfer RNA -mediated antitermination in vitro 显示文摘 | Putzer H Condon C Brechemier - Baey D Brito R Grunberg - Manago M | 2002 | Nucleic Acids Research2002，30，14： | 1 |
| 20 | Catalytic wet air oxidation of aqueous solutions of substituted phenols显示文摘 | POSADA D BETANCOURT P LIENDO F BRITO J L | 2006 | Catalysis Letters2006，106，12： | 1 |
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