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| 1 | Efficacy of neoadjuvant therapy and surgical rescue for locally advanced hepatoblastomas:10 year single-center experience and literature review显示文摘AIM:To report our experience with long-term outcomes after multimodal management therapy.METHODS:An observational retrospective study was performed containing seven patients with hepatoblastoma(Hbl)treated in our institution,a tertiary referral center,from 2003 to 2011.Demographic,preoperative,surgical,and outcome variables were collected.A survival analysis and a review of the current literature related to combination neoadjuvant chemotherapy and surgical resection on Hbl were performed.RESULTS:The median age at surgery was 14.4 mo,with a male to female ratio of 4:3.Pretext staging at diagnosis was as follows:stageⅠ,4 cases;stageⅡ,2 patients;and stageⅢ,1 case.Mean pretreatment tumor volume was 735 cm3.Five out of seven patients received neoadjuvant chemotherapy according to SIOPEL-3 or SIOPEL-6 protocols.Tumor volume and alphafetoprotein levels significantly dropped after neoadjuvant therapy.Surgical procedures performed included hemihepatectomies,segmentectomies and atypical resection.All patients received chemotherapy after surgery.Median postoperative hospital stay was 8 d.All patients were alive and disease-free after a median follow-up period of 23 mo.With regards to the literature review,seventeen articles were found that were related to our search.CONCLUSION:Our series shows how multimodal management of Hbl,exhaustive control and a meticulous surgical approach leads to almost 100%complete resection with optimal postoperative results. | Dolores Ayllon Teran Oscar Gómez Beltran Rubén Ciria Bru Elena Mateos González María José Pea Rosa Antonio Luque Molina Pedro López Cillero Javier Briceo Delgado | 2014 | World Journal of Gastroenterology2014，20，29： | 12 |
| 2 | Electron hole recombination emission as a probe of surface chemistry in aqueous CdS colloids 显示文摘 | ROSSETTI R BRUS L | 1982 | J Phys Chem1982，86，172： | 1 |
| 3 | Specific gonadotropinreleasing hormone analogue binding predominantly in human luteinized follicular aspirates and not in human preovulatory follicles显示文摘 | Brus L Lambalk CB De Koning J | 1997 | Hum Reprod1997，12，： | 1 |
| 4 | Level Ⅳ fugacity model depending on temperature by a periodic control system显示文摘 | Paraiba L C Bru R Carrasco J M | 2002 | Ecological Modelling2002，147，3： | 1 |
| 5 | Simple model for the ionization potential, electron affinity, and aqueous redox potential of small semiconductor crystallites 显示文摘 | BRUS L E A | 1983 | J Chem Phys1983，79，： | 1 |
| 6 | Electronic wave functions in semiconductor clusters:experiment and theory 显示文摘 | BRUS L | 1986 | J Phys Chem1986，90，： | 1 |
| 7 | Electron-electron and electron-hole interactions in small semiconductor crystallites:The size dependence of the lowest excited electronic state显示文摘 | BRUS L E | | 0，，09： | 1 |
| 8 | Noble metal nanoparticles: Plasmon electron transfer photochemistry and single-molecule Raman spectroscopy显示文摘 | BRUS L | 2008 | Accounts of Chemical Research2008，41，12： | 1 |
| 9 | Silver nanodisk growth by surface plasmon enhanced photoreduction of adsorbed 显示文摘 | MAILLARD M HUANG P BRUS L | 2003 | Nano Letters2003，3，11： | 1 |
| 10 | Tuning intermolecular attraction to create polar order and one-dimensional nanostructures on surfaces 显示文摘 | Nguyen T Q Bushey M L Brus L E | 2002 | J Am Chem Soc2002，124，15： | 1 |
| 11 | Nanoscale Atoms in Solid- State Chemistry 显示文摘 | Roy X Lee C H Crowther A C Schenck C L Besara T Lalancette R A Siegrist T Stephens P W Brus L E Kim P Steigerwald M L Nuckolls C | 2013 | Science2013，，341： | 1 |
| 12 | Electron- electron and electron-hole interactions in small small semiconductor crystallites:The size dependence of lowest excited electronic state显示文摘 | Brus L E | 1984 | J Chem Phys1984，80，9： | 1 |
| 13 | Electronic wave function in semiconductor cluster : experiment and theory 显示文摘 | L E Brus | 1986 | Phys Chem1986，90，12： | 1 |
| 14 | 显示文摘 | Brus L E | 1984 | J Chem Phys1984，80，9： | 1 |
| 15 | Fast Surface Diffusion of Large Disk-Shaped Nanocrystal Aggregates 显示文摘 | G Ge L E Brus | 2001 | Nanoletter2001，1，4： | 1 |
| 16 | Zero-Dimensional 'Excitons' in Semiconductor Clusters显示文摘 | Brus L E | 1986 | IEEE Journal of Quantum Electron1986，22，9： | 1 |
| 17 | Electron-electron and electron-hole interactions in small semiconductor crystallites:The size dependence of the lowest excited electronic state显示文摘 | Brus L E | 1984 | The Journal of Chemical and Physics1984，80，9： | 1 |
| 18 | A simple generalization of Gersgorin's theorem显示文摘 | CVETKOVIC L KOSTIC V BRU R | 2011 | Advances in Computational Mathematics2011，35，： | 1 |
| 19 | Systematic review of randomized trials for unresectablehepatocellular carcinoma: chemoembolization improves survival显示文摘 | L lovet JM Bru ix J | 2003 | Hepatology2003，37，2： | 1 |
| 20 | Determination of melatonin in biological fluids in the presence of the melatonin agonist $20098: comparison of immunological techniques and GC-MS methods显示文摘 | Simonin G Bru L Lelievre E | 1999 | J Pharm Biomed Anal1999，21，3： | 1 |
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