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| 1 | Mouse models in male fertility research显示文摘男不孕的基因原因的有限知识导致了很少处理并且指向了治疗学的选择。尽管识别引起变化的不孕的理想的途径是在人的人口进行研究,这条途径由于此处描述的限制慢慢地进行了。给男富饶的复杂性,全部过程不能在 vitro 被建模。因此,动物当模特儿,特别地老鼠模型,为基因鉴定和试验提供一种珍贵选择。自从在动物模型生产的分子的生物学和最近的进展的介绍,在与许多疾病联系的基因的鉴定和描述有实质的加速,包括不孕。老鼠模型的三种主要类型通常在生物医学的研究被使用,包括 knockout/knockin/gene-trapped,转基因、导致化学药品的点异种老鼠。使用这些老鼠模型,在为男富饶的 400 基因必需品上被揭示了。然而,几千基因涉及男富饶的复杂过程的规定,这被估计了,当许多如此的基因尚待被描绘。当前的评论绝非是这些鼠标模型,的一张全面的表相当,它包含鼠标模型怎么推进了我们出生后的细菌房间开发和男富饶规定的知识的例子。 | Duangporn Jamsai Moira K O'Bryan | 2011 | Asian Journal of Andrology2011，13，1： | 10 |
| 2 | The role of cysteine-rich secretory proteins in male fertility显示文摘充满半胱氨酸的能分泌的蛋白质(CRISPs ) 是 CRISP,的亚群抗原 5 并且 Pr-1 (帽子) 蛋白质总科,并且仅仅在脊椎动物被发现。他们显示出强壮的表示偏爱到哺乳动物的男繁殖的道和有毒的爬行动物的毒液。在男繁殖的道以内, CRISPs 在跨越 haploid 细菌房间开发, epididymal 成熟, capacitation,活动性和授精的实际进程的男细菌房间生物学的许多方面被含有。在结构的水平, CRISPs 由二个领域,一个帽子领域,它在房间鈥揷e ll 粘附被含有,和一个松脆的领域组成,它被显示了越过多重种类调整离子隧道的几个班。此处,我们将在男富饶在 CRISPs 的角色上考察当前的文学,并且由到相关非哺乳动物的蛋白质的推理,推断潜在的生物化学的功能。 | Adam J Koppers Thulasimala Reddy Moira K O'Bryan | 2011 | Asian Journal of Andrology2011，13，1： | 8 |
| 3 | The central role of wear debris in periprosthetic osteolysis显示文摘 | Edward P Panagiotis K Bryan J N | 2006 | Hospital for Special Surgery Journal2006，2，： | 1 |
| 4 | Petri net modeling and design of task oriented messaging system for robot control显示文摘 | Mo John P T Tang Bryan C K | 1998 | Computers & Industrial Engineering1998，34，4： | 1 |
| 5 | Immunohistichemical localization of endothelial nitric oxide synthase in human testis,epididymis,and vas deferens suggests a possible role for nitric oxide in spermatogenesis,sperm maturation,and programmed cell death 显示文摘 | Zini A O'Bryan M K Magid M S etal | 1996 | Bio Reprod1996，55，： | 1 |
| 6 | Endothelium-dependent vasodilation of cerebral arteries is altered with simulated microgravity through nitric oxide synthase and EDHF mechanisms显示文摘 | Prisby RD Wilkerson K Sokoya EM Bryan RM Wilson E Delp MD | 2006 | Appl Physiol2006，，： | 1 |
| 7 | Nitric oxide synthase activi ty in human seminal plasma 显示文摘 | Zini A O'Bryan M K Schlegel P N | 2001 | Urology2001，58，1： | 1 |
| 8 | Overview of hypemricaemia and gout 显示文摘 | Masseoud D Rott K Liu - Bryan R | 2005 | Currpharm Des2005，11，32： | 1 |
| 9 | In vitro osteogenic potential of an experimental calcium silicate-based root canal sealer 显示文摘 | Bryan TE Kheehen K Brackett MG | 2010 | J Endod2010，36，7： | 1 |
| 10 | A single amino acid difference distinguishes resistant and susceptible alleles of the rice blast resistance gene Pi-ta显示文摘 | Bryan G T Wu K S Farrall L | 2000 | Plant Cell2000，12，11： | 1 |
| 11 | Climate calculations with a combined ocean - atmosphere model显示文摘 | Manabe S Bryan K | 1969 | Journal of the Atmospheric Sciences1969，26，4： | 1 |
| 12 | Sphingosine 1-phosphate and interleukin 1 independently regulate plasminogen activator inhibitor 1 and urokinase type piasminogen activator receptor expression in glio blastoma cells: implications for invasiveness 显示文摘 | Bryan L Paugh B S Kapitonov D Wilczynska K M Alvarez S M Singh S K | 2008 | Mol Cancer Res2008，6，： | 1 |
| 13 | Repression of an altemative mechanism for lengthening of telomeres in somatic cell hybrids 显示文摘 | Perrem K Bryan T M Englezou A | 1999 | Oncogene1999，18，： | 1 |
| 14 | Mapping QTLs for resistance to the cyst nematode Globodera palli da derived from the wild potato species Solanum vernei显示文摘 | Bryan G Mclean K Bradshaw E | 2002 | TAG2002，105，： | 1 |
| 15 | Identification of the DNA Binding specificity and potential target genes for the farnesold X-activated receptor显示文摘 | Bryan A L Heidi R K Catherine M N | 2000 | J Biol Chem2000，275，10： | 1 |
| 16 | The novel angiotensin-converting enzyme(ACE)homolog,ACE2is selectively expressed by adult Leydig cells of the testis显示文摘 | Douglas G C O’Bryan M K Hedger M P | 2004 | Endocrinology2004，145，13： | 1 |
| 17 | Congruent composition and Li-rich phase boundary of LiNbO3显示文摘 | O′BRYAN H M GALLAGHER P K BRANDLE C D | 1985 | J Am Ceram Soc1985，68，9： | 1 |
| 18 | Logistics planning under uncertainty for disposition of radioactive wastes 显示文摘 | List George F Wood Bryan Turnquist Mark A Nozick Linda K Jones Dean A Lawton Craig R | 2006 | Computers and Operations Research2006，33，3： | 1 |
| 19 | Male infertility genetics-the future显示文摘 | Cram D S O'Bryan M K de Kretser D M | 2001 | J Androl2001，22，5： | 1 |
| 20 | The effect of CO2 availability on the growth, iron oxidation and CO,-fixation rates of pure cultures of Leptospirillum Jerriphilum and Acidithiobacillus Jerrooxidans 显示文摘 | BRYAN C G DAVIS-BELMAR C S van WYK N FRASER M K DEW D RAUTENBACH G F HARRISON | 2012 | Biotechnology and Bioengineering2012，109，7： | 1 |
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