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12篇 您的检索式：作者名="Bubke"

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		题名	作者	年代	出处	被引量
	1	The chemokine receptor CCR7 is a promising target for rheumatoid arthritis therapy显示文摘The chemokine receptor CCR7 and its ligands CCL19 and CCL21 guide the homing and positioning of dendritic and T cells in lymphoid organs,thereby contributing to several aspects of adaptive immunity and immune tolerance.In the present study,we investigated the role of CCR7 in the pathogenesis of collagen-induced arthritis(CIA).By using a novel anti-human CCR7 antibody and humanized CCR7 mice,we evaluated CCR7 as a target in this autoimmune model of rheumatoid arthritis(RA).Ccr7-deficient mice were completely resistant to CIA and presented severely impaired antibody responses to collagen II(CII).Selective CCR7 expression on dendritic cells restored arthritis severity and anti-CII antibody titers.Prophylactic and therapeutic treatment of humanized CCR7 mice with anti-human CCR7 mAb 8H3-16A12 led to complete resistance to CIA and halted CIA progression,respectively.Our data demonstrate that CCR7 signaling is essential for the induction of CIA and identify CCR7 as a potential therapeutic target in RA.	Georgios L.Moschovakis Anja Bubke Michaela Friedrichsen Jasmin Ristenpart Jaap Willem Back Christine S.Falk Elisabeth Kremmer Reinhold Forster	2019	Cellular & Molecular Immunology2019，16，10：	3
	2	Estimating Medical Resources Required following a Nuclear Event 显示文摘	Abend M Bubk O Hotop S	1999	Computers in Biology and Medicine1999，，29：	1
	3	Alloantigen-specific de novo-induced Foxp3+ Tregs revert in vivo and do not protect from experimental GVHD 显示文摘	Koenecke C Czeloth N Bubke A	2009	Eur J Immunol2009，39，：	1
	4	Optical Anisotropy of Dispersed Carbon Nanotubes Induced by an Electric Field显示文摘	Bubke K Gnewuch H Hempstead M	1997	Appl Phys Lett1997，71，14：	1
	5	Optical anisotropy ofdispersed carbon nanotubes induced by an electric field显示文摘	Bubke K Gnewuch H Hempstead M	1997	Applied Physics Letters1997，71，：	1
	6	Optical anisotropy of dispersed carbon nanotubes induced by an electric filed 显示文摘	Bubke K Gnewuch H Henpstead M	1997	Appl Phys Lett1997，71，14：	1
	7	Optical anisotropy of dispersed carbon nanotubes induced by an electric field显示文摘	Bubke K Gnewuch H Hempstead M		0，，：	1
	8	Asymmetric catalytic hydrogenation reactors in supercritical carbon dioxide显示文摘	BUBK M J FENC S CBOSS M F TUMAS W J	1995	J Am Chem Soc1995，117，：	1
	9	Deficient CCR7 signaling promotes TH2 polarization and B-cell activation in vivo 显示文摘	Moschovakis G L Bubke A Dittrich-Breiholz O	2012	Eur J Immunol2012，42，1：	1
	10	Estimating medical resources required following a nuclear event 显示文摘	Abend M Bubk O Hotop S	1999	Computers in Biology and Medicine1999，29，：	1
	11	Determination of Mask induced polarization effects occurring in Hyper NA immersion lithography显示文摘	Silvio Teuber Karsten Bubke Ingo Hollein	2005	SPIE2005，5754，：	1
	12	Deficient CCR7 signaling promotes TH2 polarization andB-cell activation invivo显示文摘	Moschovakis GL Bubke A Dittrich Breiholz 0	2012	Eur J Immunol2012，42，1：	1

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