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| 1 | Evolution and predictive factors of thyroid disorder due to interferon alpha in the treatment of hepatitis C显示文摘AIM:To study predictive factors of thyroid dysfunction associated with interferon-alpha(IFNα) therapy in chronic hepatitis C(CHC) and to describe its long-term evolution in a large population without previous thyroid dysfunction.METHODS:We performed a follow-up of thyroid function and detection of thyroid antibodies in 301 patients treated for CHC with IFNα from 1999 to 2004.RESULTS:Thyroid disorder developed in 30/301(10%) patients with a mean delay of 6 ± 3.75 mo:13 patients had hyperthyroidism,11 had hypothyroidism,and 6 had biphasic evolution.During a mean follow-up of 41.59 ± 15.39 mo,9 patients with hyperthyroidism,3 with hypothyroidism,and 4 with biphasic evolution normalized thyroid function in 7.88 ± 5.46 mo.Recovery rate of dysthyroidism was not modified by treatment discontinuation,but was better for patients with negative thyroid antibodies before antiviral treatment(P = 0.02).Women had signif icantly more dysthyroidism(P = 0.05).Positive thyroid peroxidase and thyroglobulin antibodies were more frequent before antiviral treatment in patients who developed dysthyroidism(P < 0.0003 and P = 0.0003,respectively).In a multivariate model,low fibrosis was found to be a predictive factor of dysthyroidism(P = 0.039).CONCLUSION:In this monocentric population of CHC,dysthyroidism,especially hyperthyroidism,developed in 10% of patients.Low fibrosis was found to be a predictive factor of dysthyroidism.Thyroid disorder recovered in 16/30 patients(53%) and recovery was better in the non-autoimmune form. | Moana Gelu-Simeon Aurore Burlaud Jacques Young Gilles Pelletier Catherine Buffet | 2009 | World Journal of Gastroenterology2009，15，3： | 8 |
| 2 | Do males choose their mates in the lekking moth Achroia grisella? Influence of female body mass and male reproductive status on male mate choice显示文摘Lekking 男性聚集吸引女性并且完全作出贡献到鸡蛋授精,没有更进一步父母的照顾。进化理论因此预言他们是向他们的配偶的 nonchoosy,因为任何失去的交配机会将超过与如此的偏爱联系的好处。但由于时间费用,精力充沛地昂贵的性显示的生产,和潜在的精子限制, lekking 男性的交配努力经常是可观的。这些因素,与改变质量的许多女性是可能的访问列克的事实结合了,能赞成男配偶偏爱的进化。这里,我们证明 lekking 的男性更小的蜡蛾, Achroia grisella,确实,对与在选择实验的更重的女性,一起的配偶可能的更多在他们交配的处女弄平(即,他们的繁殖资源什么时候还没有,被以前的 matings 弄空) 。当重、轻的女性显示了类似的动机交配,这微分女性的交配成功不能被归因于女行为(即,走近男性的潜伏) 并且交接的时间。男性们似乎得益于与更重的女性一起交配,当肥沃断然与女质量相关。这条新实验证据证明那种男配偶选择可能在 lekking 种类被低估了。 | Marlene Goubault Rebecca Burlaud | 2018 | Insect Science2018，25，5： | 2 |
| 3 | Rain Retrieval from TMI brightness Temperature Measurements Using a TRMM PR - based Database显示文摘 | Nicolas Viltard Corinne Burlaud | 2006 | Journal of Applied Meteorology and Climatology2006，45，3： | 1 |
| 4 | Mortality and bloodstream infections in geriatrics units显示文摘 | Aurore Burlaud Danièle Mathieu Bruno Falissard Christophe Trivalle | 2010 | Archives of Gerontology and Geriatrics2010，，： | 1 |
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