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| 1 | Measurement of circulating levels of VEGF-A,-C,and -D and their receptors,VEGFR-1 and -2 in gastric adenocarcinoma显示文摘AIM: To analyze the serum levels and prognostic significance of vascular endothelial growth factor (VEGF) -A,-C,and -D,and their receptors,VEGFR-1 and -2 in gastric adenocarcinomas. METHODS: The serum levels of VEGF family members were measured in 76 control subjects and 76 patients with gastric adenocarcinoma using an enzyme-linked immunosorbent assay (ELISA). These measurements were correlated with clinco-pathological features and survival rates. RESULTS: The serum levels of VEGF-A and its receptor,VEGFR-1,were signifi cantly higher in patients with gastric cancer than in healthy donors (t = 2.3,P = 0.02 and t = 4.2,P < 0.0001,respectively). In contrast,the serum levels of VEGF-D were signif icantly higher in control subjects than in patients (t = 2.9,P = 0.004). There was no significant difference in serum levels of VEGF-C and VEGFR-2 between patients and controls. VEGF-C was associated with advanced tumor stage and presence of metastasis. VEGFR-1 was associated with metastasis,advanced overall stage,tumor differentiation and survival. VEGFR-2 levels were associated with poor tumor differentiation. There was no significant prognostic value for any of the VEGF family members or their receptors except for VEGFR-1 where high levels were associated with a poor overall survival. CONCLUSION: Serum VEGF levels vary significantly in the same cohort of patients with variable clinico-pathological features and prognostic values. The simultaneous measurement of VEGF receptors levels in sera may overcome the limitations of a single biomarker assay. | Mansour S Al-Moundhri A Al-Shukaili M Al-Nabhani B Al-Bahrani IA Burney A Rizivi SS Ganguly | 2008 | World Journal of Gastroenterology2008，14，24： | 32 |
| 2 | Excretion of collagen derived peptides is incorased in women with stress urinary incontinence 显示文摘 | Kushner L Mathrubutham M Burney T | 2004 | Neurourol Urody2004，23，3： | 1 |
| 3 | Excretion of collagen derived peptides is increased in women with stress urinary incontinence显示文摘 | KUSHNER L MATHRUBUTHAM M BURNEY T | 2004 | Neurourol Urodyn2004，23，3： | 1 |
| 4 | Detection of Toxoplasma gondii parasitemia in experimentally inoculated cats 显示文摘 | BURNEY D P LAPPIN M R SPILKER M | 1999 | J Parasitol1999，85，5： | 1 |
| 5 | Excretion of collagen derived peptides is increased in women with stress urinary incontinence显示文摘 | Kushner L Mathrubutham M Burney T | 2004 | Neurourol Urodyn2004，23，3： | 1 |
| 6 | A refined fuzzy time series mod- el for stock market forecasting 显示文摘 | Jilani T A Burney S M A | 2008 | Physica A: Statistical Mechanics and its Applications2008，387，12： | 1 |
| 7 | Acute cerebrovascular accident and lower urinary tract dysfunction:a prospective correlation of the site of brain injury with urodynamic findings显示文摘 | Burney TL Senapati M Desai S | 1996 | J Urol1996，156，： | 1 |
| 8 | Computer design of a multi-purpose minimum vibration face milling cutter显示文摘 | Doolan P Burney F E Wu S M | 1976 | International Journal of Machine Tools Design research1976，16，18： | 1 |
| 9 | Acute cerebrovascular accident and lower urinary tract dysfunction:a prospective correlation of the site of brain injury with urodynamic findings显示文摘 | Burney TL Senapati M Desai S | 1996 | J Uro1996，156，： | 1 |
| 10 | Acute cerebrovascular accident and lower urinary tract dysfunction: a prospective cor- relation of the site of brain injury with urodynamic findings 显示文摘 | Burney TL Senapati M Desai S | 1996 | J Urol1996，156，： | 1 |
| 11 | Efficacy of Sublobar Resection With 125I Brachymesh at Two Years for Early Stage Non-Small Cell Lung Cancer (NSCLC)显示文摘 | Manning M Burney D Bryant C | | 0，，1： | 1 |
| 12 | Acute Cerebro- vascular Accident and Lower Urinary Tract Dysfunction: A Prospective Correlation of the Site of Brain Injury with Urodynamic Findings显示文摘 | Burney T L Senapati M Desai S | 1996 | J Urol1996，156，5： | 1 |
| 13 | Acute eerebrovascular ceident and lower uri- nary tract dysfunction : a prospective correlation of the site of brain in- jury withurodynamic findings 显示文摘 | Burney TL Senapati M | 1996 | J Urol1996，156，5： | 1 |
| 14 | Early detection and treatment of severe sepsis in the emergency depart- ment:identifying barriers to implementation of a protocol - based approach 显示文摘 | Burney M Underwood J McEvoy S | 2012 | Journal of Emergency Nursing2012，38，6： | 1 |
| 15 | Outcome of vaportrode transurethral vaporization of the prostate using pressure-flow urodynamic criteria显示文摘 | Burney T L Diaz P A | 1998 | Urology1998，51，6： | 1 |
| 16 | A stochastic ap- proach to characterization of machine tool system dy- namics under actual working conditions显示文摘 | Burney F A Pandit S M Wu S M | 1976 | Journal of Manufacturing Science and Engineering1976，98，2： | 1 |
| 17 | Mulching Potatoes: Aspects of mulch management systems and soil erosion显示文摘 | Edwards L M Volk A Burney J R | 2000 | American Journal of Potato Research2000，77，4： | 1 |
| 18 | Mulching pota-toes : Aspects of mulch management systems and soil e- rosion显示文摘 | Edwards L M Volk A Burney J R | 2000 | American journal of potato research2000，77，22： | 1 |
| 19 | The nutritional supplement chromium picolinate generates oxidative DNA damage and peroxidised lipids in vivo显示文摘 | HEPBURN D D D BURNEY J M WOSKI S A | 2003 | Polyhedron2003，22，： | 1 |
| 20 | Response of ran dom skin flaps to rapid expansion显示文摘 | Marks M W Mackenzie J R Burney R E | 1985 | J Trauma1985，25，10： | 1 |
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