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| 1 | Thyroid hormone receptor isoforms localize to cardiac mitochondrial matrix with potential for binding to receptor elements on mtdna显示文摘 | Morrish F Buroker N E Ge M | | 0，，： | 1 |
| 2 | Length heteroplasmy of sturgeon mitochondrial DNA: An illegitimate elongation model显示文摘 | BUROKER N E BROWN J R GILBERT T A | 1990 | Genetics1990，124，1： | 1 |
| 3 | Identifying changes in punitive transcriptional factor binding sites from regulatory single nucleotide polymorphisms that are significantly associated with disease or sickness显示文摘AIM To identify punitive transcriptional factor binding sites(TFBS) from regulatory single nucleotide polymorphisms(rS NPs) that are significantly associated with disease.METHODS The genome-wide association studies have provided us with nearly 6500 disease or trait-predisposing SNPs where 93% are located within non-coding regions such as gene regulatory or intergenic areas of the genome. In the regulatory region of a gene, a SNP can change the DNA sequence of a transcriptional factor(TF) motif and in turn may affect the process of gene regulation. SNP changes that affect gene expression and impact gene regulatory sequences such as promoters, enhancers, and silencers are known as rS NPs. Computational tools can be used to identify unique punitive TFBS created by rS NPs that are associated with disease or sickness. Computational analysis was used to identify punitive TFBS generated by the alleles of these rS NPs.RESULTS r SNPs within nine genes that have been significantly associated with disease or sickness were used to illustrate the tremendous diversity of punitive unique TFBS that can be generated by their alleles. The genes studied are the adrenergic, beta, receptor kinase 1, the v-akt murine thymoma viral oncogene homolog 3, the activating transcription factor 3, the type 2 demodkinase gene, the endothetal Per-Arnt-Sim domain protein 1, the lysosomal acid lipase A, the signal Transducer and Activator of Transcription 4, the thromboxane A2 receptor and the vascular endothelial growth factor A. From this sampling of SNPs among the nine genes, there are 73 potential unique TFBS generated by the common alleles comparedto 124 generated by the minor alleles indicating the tremendous diversity of potential TFs that are capable of regulating these genes.CONCLUSION From the diversity of unique punitive binding sites for TFs, it was found that some TFs play a role in the disease or sickness being studied. | Norman E Buroker | 2016 | World Journal of Hematology2016，5，4： | 1 |
| 4 | EPASI and EGLN1 assoeiations with high altitude sickness in Hart and Tibetan Chinese at the Qinghai- Tibetan plateau显示文摘 | Buroker NE Ning XH Zhou ZN | 2012 | Blood Cells Mol Dis2012，49，12： | 1 |
| 5 | A coomassie brilliant blue G - 250 -based colorimetric assay for measuring activity of calpain and other proteases 显示文摘 | Buroker - Kilgore M Wang KK | 1993 | Anal Biochem1993，208，2： | 1 |
| 6 | Length hetero- plasmy of sturgeon mitochondrial DNA: an illegitimate e- longation model 显示文摘 | Buroker N E Brown J R Gilber T A | 1990 | Genetics1990，124，： | 1 |
| 7 | EPAS1 and EGLN1 associations with high altitude sickness in Han and Tibetan Chinese at the Qinghai Tibetan Plateau显示文摘 | Buroker NE Ning XH Zhou ZN | 2012 | Blood Cells Mol Dis2012，49，2： | 1 |
| 8 | Genetic associa- tions with mountain sickness in ban and tibetan residents at the Qinghai-tibetan plateau 显示文摘 | Buroker NE Ning XH Zhou ZN | 2010 | Clin Chim Acta2010，411，： | 1 |
| 9 | The Adaptor-Related Protein Complex 2, Alpha 2 Subunit (AP2α2) Gene is a Peroxisome Proliferator-Activated Receptor Cardiac Target Gene显示文摘 | Norman E. Buroker Jie-Yu Huang Julia Barboza Dolena R. Ledee Rocky J. Eastman Hans Reinecke Xue-Han Ning James A. Bassuk Michael A. Portman | 2012 | The Protein Journal2012，，1： | 1 |
| 10 | YEGFA SNPs and transcriptional factor binding sites associated with high altitude sickness in Han and Tibetan Chinese at the Qinghai- Tibetan Plateau 显示文摘 | Buroker N E Ning X H Zhou Z N | 2013 | J Physiol Sci2013，63，： | 1 |
| 11 | Length heteroplasmy of sturgeon mitochondrial DNA:An illegitimate elongation model 显示文摘 | Buroker NE Brown JR Gilbert TA | 1990 | Genetics1990，124，： | 1 |
| 12 | Length heteroplasmy of sturgeon mitochondrial DNA:an illegitimate elongation model显示文摘 | Buroker N E Brown J R Gilbert T A | | 0，，01： | 1 |
| 13 | EPAS1 and EGLN1 associations with high altitude sickness in Hart and Tibetan Chi- nese at the Qinghai Tibetan Plateau显示文摘 | Buroker NE Ning XH Zhou ZN | 2012 | Blood Cells Mol Dis2012，49，2： | 1 |
| 14 | Length heteroplasmy of sturgeon mitochondrial DNA: an illegitimate elongation model 显示文摘 | Buroker N E Brown J R Gilhert T A | 1990 | Genetics1990，124，： | 1 |
| 15 | Genetic associations with mountain sickness in Han and Tibetan residents at the Qinghau-Tibetan Plateau 显示文摘 | Buroker N E Ning X H Zhou Z N | 2010 | Clin Chim Acta Int J Clin Chern2010，411，： | 1 |
| 16 | AKT3, AN- GPTL4, eNOS3, and VEGFA associations with high alti- tude sickness in Han and Tibetan Chinese at the Qinghai -Tibetan Plateau显示文摘 | Buroker N E Ning X HZhou Z N | 2012 | Int J Hematol2012，96，2： | 1 |
| 17 | AKT3, NGPTL4, eNOS3,and VEGFA associations with high altitude sickness in Han and Tibetan Chinese at the Qinghai-Tibetan Plateau显示文摘 | Buroker NE Ning XH Zhou ZN | 2012 | Int J Hematol2012，96，2： | 1 |
| 18 | EPAS1 and EGLN1 asso- ciations with high altitude sickness in Han and Tibetan Chinese at the Qinghai-Tibetan Plateau显示文摘 | Buroker NE Ning XH Zhou ZN etal | 2012 | Blood Cells Mol Dis2012，49，2： | 1 |
| 19 | Moderate hypothermia (30 degrees C) maintains myocardial integrity and modi? es response of cell survival proteins after reperfusion 显示文摘 | Ning XH Chi EY Buroker NE | 2007 | Am J Physiol Heart Circ Physiol2007，293，4： | 1 |
| 20 | The identification of a(CGG)6AGG insertion within the CGG repeat of the FMR1 genein Asians显示文摘 | Chen SH Schoof JM Buroker NE | 1997 | Hum Genet1997，99，6： | 1 |
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