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| 1 | 左心质量与脑磁共振成像和认知功能的关系显示文摘左心室质量(1eft ventricularmass,LVM)被证实可以作为长期暴露于数个危险因素下时造成的靶器官损害的评估标准。有关中年LVM和晚期认知表现之间联系的资料很少。纳入StrongHeart研究(SHS,1993—1995)及其附属的CDCAI(脑血管病及其对美国印第安人的影响)研究(2010—2013)中721名成年研究对象(平均基础年龄56岁),这些人群心血管病风险较高。 | 黄洁 叶鹏 Haring B Omidpanah A Suchy Dicey AM Best LG Verney SP Shibata DK Cole SA Ali T Howard BV Buchwald D Devereux RB | 2017 | 中华高血压杂志2017，25，10： | 4 |
| 2 | Interferon-γ inhibits ghrelin expression and secretion via a somatostatin-mediated mechanism显示文摘AIM:To investigate if and how the proinflammatory cytokine interferon γ(IFNγ) affects ghrelin expression in mice.METHODS:The plasma concentration of ghrelin,andgastric ghrelin and somatostatin expression,were examined in wild-type mice and mice infected with Helicobacter pylori(H.pylori).Furthermore,ghrelin expression was examined in two achlorhydric mouse models with varying degrees of gastritis due to bacterial overgrowth.To study the effect of IFNγ alone,mice were given a subcutaneous infusion of IFNγ for 7 d.Finally,the influence of IFNγ and somatostatin on the ghrelin promoter was characterized.RESULTS:H.pylori infection was associated with a 50% reduction in ghrelin expression and plasma concentration.Suppression of ghrelin expression was inversely correlated with gastric inflammation in achlorhdyric mouse models.Subcutaneous infusion of IFNγ suppressed fundic ghrelin mRNA expression and plasma ghrelin concentrations.Finally,we showed that the ghrelin promoter operates under the control of somatostatin but not under that of IFNγ.CONCLUSION:Gastric infection and inflammation is associated with increased IFNγ expression and reduced ghrelin expression.IFNγ does not directly control ghrelin expression but inhibits it indirectly via somatostatin. | Jesper AB Strickertsson Kristina BV DΦssing Anna JM Aabakke Hans-Olof Nilsson Thomas VO Hansen Ulrich Knigge Andreas Kjr Torkel Wadstrm Lennart Friis-Hansen | 2011 | World Journal of Gastroenterology2011，17，26： | 2 |
| 3 | Prevalence of anxiety and depression among chronic bronchitis patients and the associated factors 显示文摘 | Miguel D J Hernandez BV Puente ML | 2011 | Respirology2011，16，7： | 1 |
| 4 | Designing a GPS-based mini wave buoy显示文摘 | Vries J J Bv D | 2007 | International Ocean Systems2007，11，3： | 1 |
| 5 | Sleep and epilepsy显示文摘 | Vaughn BV D' Cruz OF | 2004 | Semin Neuro J2004，24，2： | 1 |
| 6 | Spermatogonial apoptosis has three morphologically recognizable phases and shows no circadian rhythm during normal spermatogenesis in the rat显示文摘 | Allan D J Harmon BV Roberts SA | 1992 | Cell Prolif1992，25，2： | 1 |
| 7 | Complement evasion by human Pathogens显示文摘 | Lambris JD Ricklin D Geisbrecht BV | 2008 | Nat Rev Microbiol2008，6，2： | 1 |
| 8 | From workplace air measurement results toward estimates of exposure? Development of a strategy to assess exposure to manufactured nano -objects 显示文摘 | Brouwer D Duuren - Stuurman BV Berges M | 2009 | J Nanopart Res2009，11，8： | 1 |
| 9 | The voltage-dependent anion channel:characterization,modulation,and role in mitochondrial function in cell life and death显示文摘 | Shoshan BV Gincel D | 2003 | Cell Biochem Biophys2003，39，3： | 1 |
| 10 | Obstructive sleep apnea in epilepsy 显示文摘 | Vaughn BV D'Cruz OF | 2003 | Clin Chest Med2003，24，2： | 1 |
| 11 | Value of nucleated red blood cell in predicting severity and outcome of perinatal asphyxia Indian显示文摘 | Ferns SJ Bhat BV Basu D | 2004 | J Pathol M icrobiol2004，47，4： | 1 |
| 12 | A role for alphal tubulin-expressingMuller glia in regeneration of the injured zebrafish retina 显示文摘 | Fausett BV Goldman D | 2006 | JNeurosci2006，26，23： | 1 |
| 13 | Expression of p53 protein in normal,dys plastic,and malignant gastric mucosa:an immunohistochemical study显示文摘 | Joypaul BV Newman EL Hopwood D | 1993 | J Pathol1993，170，： | 1 |
| 14 | Coupling of angiogenesis and neurogenesis in cultured endothelial cells and neural progenitor cells after stroke显示文摘 | Teng H Zhang ZG Wang L Zhang RL Zhang L Morris D Gregg SR Wu Z Jiang A Lu M Zlokovic BV Chopp M | | 0，，： | 1 |
| 15 | Stress - Induced Depression Is Alleviated by Aerobic Exercise Through Up -Regulation of 5 - Hydroxytryptamine 1A Receptors in Rats 显示文摘 | Kim TW Lim BV Baek D Ryu DS Seo JH | 2015 | Int Neurourol J2015，，19： | 1 |
| 16 | Efficacy of cognitive rehabilitation in patients with mild cognitive impair ment treated with eholinesterase inhibitors显示文摘 | Rozzini L Costardi D Chilovi BV | 2007 | Int J Geriatr Psychiatr2007，22，： | 1 |
| 17 | 显示文摘 | McCleary BV Monaghan D | 2002 | J AOAC Int2002，85，： | 1 |
| 18 | Value of nucleated red blood cells in predicting severity and outcome of perinatal asphyxia显示文摘 | Ferns SJ Bhat BV Basu D | 2004 | Indian J Pathol Microbio12004，47，： | 1 |
| 19 | Measurement of alpha-amylase activity in white wheat flour, milled malt, and microbial enzyme preparations, using the Ceralpha assay: Collaborative study显示文摘 | McNally M Monaghan D | 2002 | AOAC Int2002，85，5： | 1 |
| 20 | HPLC as a replacement for the animal response assays for insulin 显示文摘 | Fisher BV Smith D | 1986 | J Pharmaceut Biomed1986，4，： | 1 |
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