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9篇 您的检索式:作者名="Byth C"
    题名 作者 年代 出处 被引量
1Australian tertiary care outcomes of entecavir monotherapy in treatment naive patients with chronic hepatitis B显示文摘AIM:To evaluate the long-term treatment outcomes of entecavir monotherapy in treatment naive patients in an Australian tertiary care setting. METHODS:A retrospective analysis of treatment naive patients receiving entecavir monotherapy through Westmead Hospital was performed.Patients were excluded if they had received previous treatment with another nucleoside or nucleotide analogue,were pregnant or less than 18 years old. RESULTS:Out of 336 patients,163 patients fulfilled the selection criteria.Range of follow up was 3-46 mo (mean 26 mo).134 patients(82.2%)had pre-treatment biopsies,with 26 patients(16.0%)demonstrating F3-4 fibrosis.In total,153 patients(93.9%)achieved at least Partial Virological Suppression(PVS),with 134 patients (82.2%)achieving complete virological suppression. The cumulative CVS and PVS rates at 36 mo were 82.1%and 96.4%,respectively.3 patients(1.8%)failed to achieve PVS,while 5 patients(3.0%)developed virological rebound.128 patients(78.5%)maintained CVS throughout follow up.Predictors of CVS included lower baseline DNA level(P=0.001),hepatitis B virus e antigen negative status(P=0.001)and increasing age at treatment(log rank 0.001).No significant adverse effects were reported necessitating cessation of entecavir. CONCLUSION:Entecavir monotherapy is efficacious and safe in an Australian tertiary care setting.Resistance and rebound rates are very low.This is similar to data from controlled and uncontrolled trials around the world.Farzan Fahrtash-Bahin Viraj C Kariyawasam Timothy Gray Karen Byth Jacob George Mark W Douglas 2013World Journal of Gastroenterology2013,19,5:5
2Insulin resistance is associated with chronic hepatitis C and virus infection fibrosis progression显示文摘Jason M Hui Archana Sud Geoffrey C Farrell Priyanka Bandara Karen Byth James G Kench Geoffrey W McCaughan Jacob George 2003Gastroenterology2003,,6:2
3Twin-versus singe-bag disconnect systems : infection rates and cost of continuous ambulatory peritoneal dialysis 显示文摘Harris D C Yuill E J Byth K 1996J Am Soc Nephrol1996,7,11:1
4The cellular phenotype of AZ703,a novel selective imidazopyridine cyclin-dependent kinase inhibitor显示文摘Byth K F Geh C Forder C L 2007Mol Cancer Therap2007,5,:1
5Phrenic nerve injury associated with high RIMA harvesting 显示文摘Deng YZ Byth C Paterson HS 2003Ann Thorac Surgery2003,76,:1
6Virus and host factors are both important determinants of response to interferon treatment among patients with chronic hepatitis C显示文摘Lin R Liddle C Byth K 1996J Viral Hepat1996,3,2:1
7Insulin resistance is associated with chronic hepatitis C and virus infection fibrosis progression显示文摘Jason M Hui Archana Sud Geoffrey C Farrell Priyanka Bandara Karen Byth James G Kench Geoffrey W McCaughan Jacob George 2003Gastroenterology2003,,6:1
8Expression of progesterone recaptors A and B in the mouse ovary during the estrous cycle显示文摘Gava N Clarke C L Byth K 2004Endocrinology2004,145,7:1
9Novel approaches in oncology at AstraZeneca显示文摘Wheeler C Stephens T Byth K 2003EJC Supplements2003,1,8:1
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