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| 1 | Annual cycles of water vapour and carbon dioxide fluxes in and above a boreal aspen forest显示文摘 | T. A.BLACK G.HARTOG H. H.NEUMANN P.D.BLANKEN P.C.YANG C.RUSSELL Z.NESIC X.LEE S. G.CHEN R.STAEBLER M. D.NOVAK | 2006 | Global Change Biology2006，，3： | 1 |
| 2 | 在澳大利亚寻找莱姆病螺旋体显示文摘背景 1982年在澳大利亚东南部新南威尔士州捕猎山区,首次在临床上报告了具有莱姆病症状的病例。后来,1986年在该州南部和中部沿海地区又有临床病例的报告。 | Richard C.Russell 赵彤言 | 1993 | 医学动物防制1993，9，4： | 0 |
| 3 | PLGA nanodepots co-encapsulating prostratin and anti-CD25 enhance primary natural killer cell antiviral and antitumor function显示文摘Natural killer(NK)cells are attractive effector cells of the innate immune system against human immunodeficiency virus(HIV)and cancer.However,NK cell therapies are limited by the fact that target cells evade NK cells,for example,in latent reservoirs(in HIV)or through upregulation of inhibitory signals(in cancer).To address this limitation,we describe a biodegradable nanoparticlebased“priming”approach to enhance the cytotoxic efficacy of peripheral blood mononuclear cell-derived NK cells.We present poly(lactic-co-glycolic acid)(PLGA)nanodepots(NDs)that co-encapsulate prostratin,a latency-reversing agent,and anti-CD25(aCD25),a cell surface binding antibody,to enhance primary NK cell function against HIV and cancer.We utilize a nanoemulsion synthesis scheme to encapsulate both prostratin and aCD25 within the PLGA NDs(termed Pro-aCD25-NDs).Physicochemical characterization studies of the NDs demonstrated that our synthesis scheme resulted in stable and monodisperse Pro-aCD25-NDs.The NDs successfully released both active prostratin and anti-CD25,and with controllable release kinetics.When Pro-aCD25-NDs were administered in an in vitro model of latent HIV and acute T cell leukemia using J-Lat 10.6 cells,the NDs were observed to prime J-Lat cells resulting in significantly increased NK cell-mediated cytotoxicity compared to free prostratin plus anti-CD25,and other controls.These findings demonstrate the feasibility of using our Pro-aCD25-NDs to prime target cells for enhancing the cytotoxicity of NK cells as antiviral or antitumor agents. | Elizabeth E.Sweeney Preethi B.Balakrishnan Allison B.Powell Allan Bowen Indra Sarabia Rachel A.Burga R.Brad Jones Alberto Bosque C.Russell Y.Cruz Rohan Fernandes | 2020 | Nano Research2020，13，3： | 0 |
| 4 | Diet analysis of small mammal pests: A comparison of molecular and microhistological methods显示文摘Knowledge of what pest species are eating is important to determine their impact on stored food products and to plan management strategies accordingly.In this study,we investigated the food habits of 2 rodents,Rattus rattus(ship rat)and Mus musculus castaneus(house mouse)as well as an insectivore,Suncus murinus(shrew),present in human dwellings.Both a microhistological approach and a DNA barcoding approach were used in the present study.Following DNA extraction,amplification was performed using group-specific primers targeting birds,plants and invertebrates.Resulting polymerase chain reaction products were sequenced and analyzed to identify the different prey species present in the gut contents.The findings from the application of both techniques were in agreement,but the detection of prey type with each technique was different.The DNA barcoding approach gave greater species-level identification when compared to the microhistological method,especially for the invertebrate and avian prey.Overall,with both techniques,23 prey taxa were identified in the gut contents of the 3 species,including 15 plants,7 insects and a single bird species.We conclude that with a selection of suitable“barcode genes”and optimization of polymerase chain reaction protocols,DNA barcoding can provide more accurate and faster results.Prey detection from either technique alone can bias the dietary information.Hence,combining prey information of both microhistological analysis and DNA barcoding is recommended to study pest diet,especially if the pest is an omnivore or insectivore species. | Surrya KHANAM Robyn HOWITT Muhammad MUSHTAQ James C.RUSSELL | 2016 | Integrative Zoology2016，11，2： | 0 |
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