|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Short and long term outcomes of 200 patients supported by continuous-flow left ventricular assist devices显示文摘AIM: To study the institutional experience over 8 years with 200 continuous-flow(CF)- left ventricular assist devices(LVAD).METHODS: We evaluated our institution's LVAD database and analyzed all patients who received a CF LVAD as a bridge to transplant(BTT) or destination therapy from March 2006 until June 2014. We identified 200 patients, of which 179 were implanted with a Heart Mate II device(Thoratec Corp., Pleasanton, CA) and 21 received a Heartware HVAD(Heart Ware Inc., Framingham, MA).RESULTS: The mean age of our LVAD recipients was 59.3 years(range 17-81), 76%(152/200) were males, and 49% were implanted for the indication of BTT. The survival rate for our LVAD patients at 30 d, 6 mo, 12 mo, 2 years, 3 years, and 4 years was 94%, 86%, 78%, 71%, 62% and 45% respectively. The mean duration of LVAD support was 581 d(range 2-2595 d). Gastrointestinal bleeding(was the most common adverse event(43/200, 21%), followed by right ventricular failure(38/200, 19%), stroke(31/200, 15%), re exploration for bleeding(31/200, 15%),ventilator dependent respiratory failure(19/200, 9%) and pneumonia(15/200, 7%). Our driveline infection rate was 7%. Pump thrombosis occurred in 6% of patients. Device exchanged was needed in 6% of patients. On multivariate analysis, preoperative liver dysfunction, ventilator dependent respiratory failure, tracheostomy and right ventricular failure requiring right ventricular assist device support were significant predictors of post LVAD survival.CONCLUSION: Short and long term survival for patients on LVAD support are excellent, although outcomes still remain inferior compared to heart transplantation. The incidence of driveline infections, pump thrombosis and pump exchange have declined significantly in recent years. | Athanasios Tsiouris Gaetano Paone Hassan W Nemeh Jamil Borgi Celeste T Williams David E Lanfear Jeffrey A Morgan | 2015 | World Journal of Cardiology2015，7，11： | 5 |
| 2 | Nat Genet:单基因突变导致过敏性皮炎的发生显示文摘最近,研究者们鉴定出了一类导致神经性皮炎发生的关键基因突变:CARDll。来自美国NIH过敏与传染病研究所的研究者们通过对四个没有血缘关系的患病家庭进行分析,发现了这一导致疾病产生的基因、 | Chi A Ma, Yuan Zhang, Michael A Weinreich, Jonathan J Lyons, Celeste G Nelson, Thomas DiMaggio, Kelly D Stone, Joshua D Milner Jeffrey R Stinson, Elisa Ruffo, Batsukh Dorjbal, Swadhinya Arjunaraja, Kelsey Voss, Andrew L Snow Jordan K Abbott, Pia J Hauk, Paul R Reynolds, Erwin W Gelfand Elisa Ruffo Salomé Glauzy, Natsuko Yamakawa, Eric Meffre Jennifer Stoddard, Julie Niemela, Sergio D Rosenzweig Yu Zhang, Helen F Matthews Joshua J McElwee Nina Jones Alejandro Palma, Matías Oleastro, Emma Prieto, Andrea R Bernasconi, Geronimo Dubra, Silvia Danielian, Jonathan Zaiat, Marcelo A Marti Brian Kim Megan A Cooper Neil Romberg | 2017 | 现代生物医学进展2017，17，27： | 3 |
| 3 | Novel reg- ulators of bone formation: molecular clones and activitles显示文摘 | WOZNEY J M ROSEN V CELESTE A J | 1988 | Science1988，242，4885： | 1 |
| 4 | Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks显示文摘 | Celeste A Femandez-Capetillo O Kruhlak MJ | 2003 | Nat Cell Biol2003，5，7： | 1 |
| 5 | Novel regu lators of bone formation: Molecular clones and activi ties显示文摘 | Wozney J M Rosen V Celeste A J | 1988 | Science1988，242，4885： | 1 |
| 6 | Novel regulators of bone formation : molecular clones and activities 显示文摘 | Wozney J M Rosen V Celeste A J | 1988 | Science1988，242，： | 1 |
| 7 | Genomic instability in mice lacking histoneH2AX显示文摘 | Celeste A Petersen S Romanienko PJ | 2002 | Science2002，296，5569： | 1 |
| 8 | Novel regula- tors of bone formation: Molecular clones and activities 显示文摘 | Wozney JM Rosen V Celeste A J | 1988 | Science1988，242，4885： | 1 |
| 9 | Novel regulators of bone formation:Molecular clones and activities显示文摘 | Wozney J M Roson V Celeste A J | 1988 | Science1988，242，： | 1 |
| 10 | DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1显示文摘 | FERNANDEZ-CAPETILLO O CHEN H T CELESTE A | 2002 | Nature Cell Biology2002，4，12： | 1 |
| 11 | Isolation of the human gene for bone gla protein utilizing mouse and rat cd- naclones 显示文摘 | Celeste A J Rosen V Buecker JL | 1986 | EMBOJ1986，5，： | 1 |
| 12 | Intrinsically disordered protein 显示文摘 | Dunker A Keith Lawson J David Brown Celeste J | 2001 | Journal of Mo- lecular Graphics and Modelling2001，19，1： | 1 |
| 13 | Novel regulators of bone formation:Molecular clones and activities显示文摘 | Wozney JM Rosen V Celeste A J | 1988 | Science1988，242，4885： | 1 |
| 14 | Genomic instability in mice lacking histone H2AX显示文摘 | Celeste A Petersen S Romanienko PJ | 2002 | Science2002，296，5569： | 1 |
| 15 | Focusing on foci:H2AX and the recruitment of DNA-damage response factors显示文摘 | Fernandez-Capetillo O Celeste A Nussenzweig A | 2003 | Cell Cycle2003，2，5： | 1 |
| 16 | Focusing on foci:H2AX and the recruitment of DNA-damage response factors显示文摘 | Fernandez-Capetil o O Celeste A Nussenzweig A | 2003 | Cell Cycle2003，2，5： | 1 |
| 17 | Myostatin:A modulator of skeletal-muscle stem cells 显示文摘 | Walsh F Celeste A J | 2005 | Biochem Soe Trans2005，33，6： | 1 |
| 18 | Genomic instability in mice lacking histone H2AX 显示文摘 | Celeste A Petersen S Romanienko PJ | 2002 | Science2002，296，5569： | 1 |
| 19 | Why do employees take more initiatives to improve their performance after co-deveh)ping performance measures? A field study显示文摘 | Bianca A C Marc J F Celeste P M | 2012 | Management ccounting Resem''ch2012，23，2： | 1 |
| 20 | Distinct domains in Nbsl regulate irradiation-induced checkpoints and apoptosis 显示文摘 | Difilippantonio S Celeste A Kruhlak MJ | 2007 | J Exp Med2007，204，5： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员