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| 1 | Effects of nanotopography on stem cell phenotypes显示文摘Stem cells are unspecialized cells that can self renew indefinitely and differentiate into several somatic cells given the correct environmental cues.In the stem cell niche,stem cell-extracellular matrix(ECM)interactions are crucial for different cellular functions,such as adhesion,proliferation,and differentiation.Recently, in addition to chemical surface modifications,the importance of nanometric scale surface topography and roughness of biomaterials has increasingly becoming recognized as a crucial factor for cell survival and host tissue acceptance in synthetic ECMs.This review describes the influence of nanotopography on stem cell phenotypes. | Rajeswari Ravichandran Clarisse CH Ng Casey K Chan Michael Raghunath Seeram Ramakrishna | 2009 | World Journal of Stem Cells2009，1，1： | 3 |
| 2 | Decomposition and Reformulation of Banxia Baizhu Tianma Decoction:A Vasodilatory Approach显示文摘Objective To decompose and reformulate Banxia Baizhu Tianma Decoction(BBT) in order to optimize its ratio for vasodilatory effect.The fingerprints of these six component herbs were also studied via Tri-step FTIR analysis.Methods The herbal components of BBT were extracted separately with different solvents,such as 95%ethanol,50%ethanol,and distilled water.The vasodilatory effect of the extracts was studied using the in vitro pre-contracted aortic ring model.Among these extracts,the water extracts of Pinellia ternata[PT(W)]and Citri reticulatae[CR(W)],50%ethanol extracts of Castrodia elata[GE(50)]and Clycyrrhiza uralensis[GU(50)],and 95%ethanol extracts of Atractylodes macrocephala[AM(E)],and Poria cocos[PC(E)]were selected for the orthogonal stimulus-response compatibility group study due to their high effectiveness in vasodilation.Results The best combination ratio(G2) was GE(50),GU(50),AM(E),PC(E),CR(W),and PT(W) at EC_0,EC_5,EC_5,EC_5,EC_5,and EC_5,with EC_(50) of(0.06 ± 0.01) mg/mL.Comparison between the vasodilatory effects of extracts derived from G2 and BBT were also studied.From the results,the 50%ethanol extract following G2 ratio was found to be most potent extract with the highest vasodilatory effect compared with other extracts derived from G2 or BBT,with EC_(50) of(0.05 ±0.005) mg/mL.Conclusion The optimum ratio and appropriate extraction method for the new BBT formulae are obtained.G2 is determined as the best formulae with the highest potency in producing the vasodilatory effect on isolated rat aortic rings.The results obtained suggest that 50%ethanol is found to be the best solvent to extract the vasoactive compounds of G2 in order to exhibit the highest efficacy of vasodilatory effect. | Chu Shan Tan Yean Chun Loh Yung Sing Ch'ng Mariam Ahmad Mohd.Zaini Asmawi Mun Fei Yam | 2017 | Chinese Herbal Medicines2017，9，2： | 3 |
| 3 | RATIONAL GENERAL SOLUTIONS OF HIGHER ORDER ALGEBRAIC ODES显示文摘This paper generalizes the method of Ngo and Winkler(2010,2011)for finding rational general solutions of a first order non-autonomous algebraic ordinary differential equation(AODE)to the case of a higher order AODE,provided a proper parametrization of its solution hypersurface.The authors reduce the problem of finding the rational general solution of a higher order AODE to finding the rational general solution of an associated system.The rational general solutions of the original AODE and its associated system are in computable 1-1 correspondence.The authors give necessary and sufficient conditions for the associated system to have a rational solution based on proper reparametrization of invariant algebraic space curves.The authors also relate invariant space curves to first integrals and characterize rationally solvable systems by rational first integrals. | HUANG Yanli NG L X Chu WINKLER Franz | 2013 | Journal of Systems Science & Complexity2013，26，2： | 3 |
| 4 | Chemical constituents and pharmacological effects of durian shells in ASEAN countries:A review显示文摘Durio zibethnus is mainly distributed in Southeast Asia.Traditional Chinese medicine believes that durian shells have the effects of clearing heat and purging fire,nourishing yin and moisturizing dryness.Therefore,it is often used as a pharmaceutic food in the Chinese folk to assist treating diseases.At present,the chemical constituents isolated from durian shell include phenolic acids,phenolic glycosides,flavonoids,coumarins,triterpenes,simple glycosides and other compounds.Modern pharmacological studies show that durian shell has many pharmacological activities,such as antioxidant,antiinflammatory,regulation of glucose and lipid metabolism.The chemical composition and pharmacological effects of durian shells are summarized in order to provide references for the further research and application of durian shell. | Yuan-fei Zhan Xiao-tao Hou Li-li Fan Zheng-cai Du Soo Ee Ch'ng Siok Meng Ng Khamphanh Thepkaysone Er-wei Hao Jia-gang Deng | 2021 | Chinese Herbal Medicines2021，13，4： | 2 |
| 5 | High-dose oral erythromycin decreased the incidence of parenteral nutrition-associated cholestasis in preterm infants 显示文摘 | Ng PC Lee CH Wong SP | 2007 | Gastroenterology2007，132，5： | 1 |
| 6 | Improving Phosphorus Availability in an Acid Soil Using Or ganic Amendments Produced from Agroindustrial Wastes显示文摘 | Huck Ywih Ch’ng Osumanu H A Nik Muhamad A b | 2014 | Hindawi2014，6，： | 1 |
| 7 | Reference ranges and factors affecting the hCRH test in preterm, very low birth weight infants显示文摘 | Ng PC Lam CWK Lee CH | 2002 | Clin Endocrinol Metab2002，87，10： | 1 |
| 8 | Requirement for the lymphocyte semaphorin, CD100, in the induction of antigenspecific T cells and the maturation of dendritic ceils 显示文摘 | Kumanogoh A Suzuki K Ch ' ng E | 2002 | J lmmunol2002，169，3： | 1 |
| 9 | Glycated hemoglobin vari&bility and retinopathy progression in type 1 di&betes:b month-to-moth inst&bility & better predictor?显示文摘 | Ch&ng CH Chu&ng LM | 2014 | J Diabetes Investig2014，5，2： | 1 |
| 10 | Distribution of the orexin-1 receptor (OX1R) in the mouse forebrain and rostral brainstem: A characterisation of OX1R-eGFP mice显示文摘 | Ch'ng SS Lawrence AJ | 2015 | J Chem Neuroanat2015，6667，： | 1 |
| 11 | Reactive oxygen species controls endometriosis progression显示文摘 | Ng? C Chéreau C Nicco C Weill B Chapron C Batteux F | 2009 | Am J Pathol2009，175，： | 1 |
| 12 | A double-blind, randomized, controlled study of a 'stress dose' of hydrocortisone for rescue treatment of refractory hypotension in preterm infants显示文摘 | Ng PC Lee CH Bnur FL | 2006 | Pediatrics2006，117，2： | 1 |
| 13 | Contamination of ribosome inactivating proteins with ribonucleases, separated by affinity chromatography on red sepharoseCJI 显示文摘 | Wang HX Ng TB Cheng CH | 2003 | Prep Biochem Biotechnol2003，33，2： | 1 |
| 14 | High-dose oral erythromycin decreased the incidence of parenteral nutrition-associated cholestasis in preterm infants显示文摘 | Ng PC Lee CH Wong SP | | 0，，05： | 1 |
| 15 | Alignment of the double- barrel fibula free flap for better cosmesis and bone height for osseointegrated dental implants显示文摘 | Ch'ng S Ashford BG Clark JR | 2013 | Plast Reconstr Surg2013，132，4： | 1 |
| 16 | Stanford type a aortic dissection in pregnancy: a diagnostic and management challenge显示文摘 | Ch' ng SL Cochrane AD Goldstein J | 2013 | Heart Lung Circ2013，22，1： | 1 |
| 17 | The mTOR/AKT inhibitor temsirolimus prevents deep infiltrating endometriosis in mice显示文摘 | Leconte M Nicco C Ng? C Chéreau C Chouzenoux S Marut W | 2011 | Am J Pathol2011，179，： | 1 |
| 18 | Relative contribution of individual oxidized components in ox-LDL to inhibition on endothelium -dependent relaxation in rat aorta显示文摘 | Wong WT Ng CH Tsang SY | 2009 | Nutr Metab Cardiovase Dis2009，21，3： | 1 |
| 19 | Interaction of the heart-specific LIM domain protein,FHL2,with DNA-binding nuclear protein,hNP220显示文摘 | Ng EK Chan KK Wong CH | 2002 | J Cell Biochem2002，84，3： | 1 |
| 20 | Ghrelin in preterm and term newborns: relation to anthropometry, leptin and insu- lin 显示文摘 | Ng PC Lee CH Lain CW | 2005 | Clin Endoerinol (Oxf)2005，63，2： | 1 |
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