|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 在不影响人足细胞(前)肾素受体信号下,阿利吉仑能抑制细胞内血管紧张素Ⅱ水平显示文摘 | Sakoda M Ichihara A Kurauchi-Mito A Narita T Kinou-chi K Murohashi-Bokuda K Saleem MA Nishiyama A Suzuki F Itoh H 黄晓斌 | 2010 | 中华高血压杂志2010,18,7: | 18 |
| 2 | Micromolar sodium fluoride mediates anti-osteoclastogenesis in Porphyromonas gingivalis-induced alveolar bone loss显示文摘Osteoclasts are bone-specific multinucleated cells generated by the differentiation of monocyte/macrophage lineage precursors.Regulation of osteoclast differentiation is considered an effective therapeutic approach to the treatment of bone-lytic diseases.Periodontitis is an inflammatory disease characterized by extensive bone resorption. In this study, we investigated the effects of sodium fluoride(Na F) on osteoclastogenesis induced by Porphyromonas gingivalis, an important colonizer of the oral cavity that has been implicated in periodontitis. Na F strongly inhibited the P. gingivalis-induced alveolar bone loss. That effect was accompanied by decreased levels of cathepsin K, interleukin(IL)-1β, matrix metalloproteinase 9(MMP9), and tartrate-resistant acid phosphatase,which were up-regulated during P. gingivalis-induced osteoclastogenesis. Consistent with the in vivo anti-osteoclastogenic effect,Na F inhibited osteoclast formation caused by the differentiation factor RANKL(receptor activator of nuclear factor kB ligand)and macrophage colony-stimulating factor(M-CSF). The RANKL-stimulated induction of the transcription factor nuclear factor of activated T cells(NFAT) c1 was also abrogated by Na F. Taken together, our data demonstrate that Na F inhibits RANKL-induced osteoclastogenesis by reducing the induction of NFATc1, ultimately leading to the suppressed expression of cathepsin K and MMP9.The in vivo effect of Na F on the inhibition of P. gingivalis-induced osteoclastogenesis strengthens the potential usefulness of Na F for treating periodontal diseases. | Ujjal K Bhawal Hye-Jin Lee Kazumune Arikawa Michiharu Shimosaka Masatoshi Suzuki Toshizo Toyama Takenori Sato Ryota Kawamata Chieko Taguchi Nobushiro Hamada Ikuo Nasu Hirohisa Arakawa Koh Shibutani | 2015 | International Journal of Oral Science2015,7,4: | 3 |
| 3 | 表面特性对耐指纹性能的影响显示文摘涂有有机树脂的电镀锌钢板不但具有良好的耐腐蚀性能,而且具有优良的耐指纹特性,因此广泛应用于家电行业。研究了指纹的可见度或污染与耐指纹涂层特性之间的关系。指纹的可见度和涂层表面的色度及反射率有关。当色度减小或反射率提高时,由于凡士林污染后,入射光和反射光之间的差异减小,指纹的可见度降低了。另一方面,指纹污染与表面自由能有关。当表面自由能减小时,凡士林残留量变少,因此耐指纹性能提高。得出的结论是:指纹的可见度和污染或许能通过降低色度、提高反射率和减小表面自由能来控制。 | H Yamaguchi T Suzuki K Mizuno 金旭芳(译) 金鑫焱(校) | 2008 | 世界钢铁2008,8,3: | 3 |
| 4 | Rapid induction of vascular endothelial growth factor gene expression after transient middle cerebral artery occlusion in rats显示文摘 | Hayashi T Abe K Suzuki H | 1997 | Stroke1997,28,10: | 2 |
| 5 | Present status and perspectives of colorectal cancer in Asia:colorectal cancer working group report at the 30th Asia-Pacific cancer conference显示文摘 | Hyodo I Suzuki H Takahashi K | | Japanese Journal of Clinical Oncology0,,: | 2 |
| 6 | Protecting effect of chitin and chitosan on experimentally induced murine candidiasis 显示文摘 | Suzuki K Okawa Y Hashimoto K | 1984 | Microbiol Immunol1984,28,: | 2 |
| 7 | Emergence and takeover of YMDD motif mutant hepatitis B virus during long-term lamivudine therapy and re-takeover by wild type after cessation of therapy显示文摘 | Chayama K Suzuki Y Kobayashi M | | 0,,: | 2 |
| 8 | Basic properties of polylactic acid produced by the direct condensation polymerization of lactic acid显示文摘 | Ajioka M Enomoto K Suzuki K Yamaguchi A | 1995 | Bull Chem Soc Jpn1995,68,8: | 2 |
| 9 | Antitumor effect of hexa-N-acetylchitohexaose and chitohexaose显示文摘 | Suzuki K Mikami T Okawa Y | 1986 | Carbohydr Res1986,151,: | 2 |
| 10 | Cyclophostin,acetylcholinesterase inhibitor from Streptomyces lavendulae 显示文摘 | Kurokawa T Suzuki K Hayaoka T | 1993 | J Antibiot (Tokyo)1993,46,8: | 2 |
| 11 | A basic study on dynamic characteristics of MR dampers显示文摘 | SODEYAMA H SUNAKODA K SUZUKI K | 2001 | Seismic Engineering ASME2001,428,2: | 2 |
| 12 | Prolonged oval cell proliferation with Ito cell activation and extracellular matrix accumulation in galactosamine-induced acute hepatitis in mini rats显示文摘 | Uetsuka K Suzuki M Nakayama H | 1997 | Histol Histopathol1997,12,4: | 2 |
| 13 | 复合性血管内皮瘤5例报道显示文摘 | Fukunaga M Suzuki K Saegusa N 李晓霞(摘译) 刘飞飞(摘译) 张仁亚(审校) | 2008 | 临床与实验病理学杂志2008,24,3: | 2 |
| 14 | 初产妇和经产妇妊娠期间的诊室和家庭血压显示文摘妊娠高血压可导致分娩时产生严重的并发症,如脑卒中、早产或低出生体质量。初产妇被认为是妊娠高血压的一个危险因素。产次与妊娠期间家庭血压相关性仍不明确。方法:入选初产妇和经产妇共575名,评估妊娠高血压和先兆子痫的发病率。收集在一家日本产科医院接受产前检查的530名正常血压孕妇的家庭和诊室血压值。诊室血压为产前检查2次测量的血压平均值,参与者妊娠期间每日清晨在家自测血压。 | Ishikuro M Obara T Metoki H Ohkubo T Yamamoto M Akutsu K Sakurai K Iwama N Katagiri M Yagihashi K Yaegashi N Mori S Suzuki M Kuriyama S Imai Y 罗冬梅 叶鹏 | 2013 | 中华高血压杂志2013,21,6: | 2 |
| 15 | ANCA相关血管炎(AAV)导致双侧脑梗死和继发性脑内出血而无肾功能和呼吸功能障碍显示文摘A 56- year-old man complained of headache and the analgesia of the four extremities. Laboratory data presented signs of inflammation, but no other abnormality such as renal or respiratory dysfunction. Two months after the appearance of the primary symptoms, he developed cerebral infarction of the bilateral corona radiata. The patient did not have any of the risk factors for cerebrovascular disease. He was diagnosed with anti-neutrophil cytoplasmic autoantibody (ANCA)associated vasculitis (AAV) because the systemic examinations revealed only that he tested positive for anti-neutrophil cytoplasmic autoantibody (ANCA). Moreover, the biopsy of the sural nerve displayed microscopic polyangitis (MPA). Despite undergoing steroid pulse therapy, the patient died from the fatal cerebral hemorrhage. The clinical course of AAV is rapid progressive. In cases of atypical cerebrovascular disease, the possibility of ANCA should be investigated. | Ito Y Suzuki K Yamazaki T 蔡同建 | 2006 | 世界核心医学期刊文摘(神经病学分册)2006,2,5: | 2 |
| 16 | Monitoring of response to radiation therapy for human tumor xenografts using^99mTc-HL91 (4,9-diaza-3,3,10,10-tetramethyldodecan-2, 11-dione dioxime) 显示文摘 | Suzuki T Nakamura K Kawase T | 2003 | Ann Nucl Med2003,17,2: | 1 |
| 17 | Pharmacological studies of human urinary kallidinogenase ( SK-827 ) : effects on arterial and regional blood flow 显示文摘 | Suzuki T Hirooka K Nakamura S et aI | 1993 | App Pharmacol1993,45,: | 1 |
| 18 | Alcohol consumption and risk for development of impaired fasting glucose or type 2 diabetes mellitus in middle-aged Japanese men 显示文摘 | Nakanishi N Suzuki K Tatara K | 2003 | Diabetes Cars2003,26,: | 1 |
| 19 | Age-related diferences in proliferarive responses of Schwann cells during Wallerian degeneration 显示文摘 | Komiyama A Suzuki K | 1992 | Brain Res1992,573,2: | 1 |
| 20 | Mutations of PVRL1, encoding a cell-cell adhesion molecule/herpesvirus receptor, in cleft lip/palateectodermal dysplasia 显示文摘 | Suzuki K Hu D Bustos T | 2000 | Nat Genet2000,25,4: | 1 |