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| 1 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014，5，2： | 5 |
| 2 | Dietaryphosphorus for beef cows 显示文摘 | CALL J W BUTCHER J E SHUPE J L | 1986 | American Journal ofVeterinary Research1986，47，2： | 1 |
| 3 | 2005 Guidelines for the diagnosis, prevention and management of heartworm( Dirofilaria immitis ) infection in dogs 显示文摘 | NELSON C T MC CALL J W RUBIN S B etal | 2005 | Vet Parasitol2005，133，3： | 1 |
| 4 | Postpartum clhanges in the uterus and blood of ewes during the anoestrous season 显示文摘 | Foote W C Call J W | 1969 | J Anita Sci1969，29，： | 1 |
| 5 | Natural revegetation ofan unreclaimed lignite surface mine in East - central Texas-USA)显示文摘 | Skousen J G Call C A Knight R W | 1990 | South-western Naturalist1990，35，9： | 1 |
| 6 | Postpartum uterine and ovarian changes, and oestrous behavior from lactation effects in normal and hormone treated ewes 显示文摘 | Call J W Foote W C Eckre C D | 1976 | Theriogenology1976，，6： | 1 |
| 7 | Discography in degenerating disc disease显示文摘 | Fraser J Mc Call I Park W | 1983 | Orthop Trans1983，7，3： | 1 |
| 8 | Endogenous folates and sin- gle-carbon metabolism in the ovarian follicle,oocyte and pre-implantation embryo显示文摘 | Kwong W Y Adamiak S J Gwynn A et call | 2010 | Reproduction (Cambridge England)2010，139，： | 1 |
| 9 | Microbial biofilms 显示文摘 | COSTERTON W J LEWANDOWSK1 Z CALl)WELL D E | 2009 | Annual Review Microbiology2009，49，： | 1 |
| 10 | Discography in degenerating disc disease显示文摘 | Fraser J Mc Call I Park W | 1983 | Orthop Trans1983，7，3： | 1 |
| 11 | Ce-ZSM-5 catalysts for the selective catalytic reduction of NOx in stationary diesel exhaust gas显示文摘 | Van KOOTEN W E J LIANG B KRIJNSEN H C OUDSHOORN O L CALLS H P A Van den BLEEK C M | 1999 | Appl Catal B1999，21，3： | 1 |
| 12 | Stoichiometry of the T-cell receptor-CD3 complex and key intermediates assembled in the endoplasmic reticulum 显示文摘 | CALL M E PYRDOL J WUCHERPFENNING K W | 2004 | EMBO J2004，23，12： | 1 |
| 13 | Stoichiometry of the T-cell receptor-CD3 complex and key intermediates assembled in the endoplasmic reticulum显示文摘 | Call M E Pyrdol J Wucherpfennig K W | 2004 | EMBO J2004，23，12： | 1 |
| 14 | Natural revegetation of an unreclaimed lignite surface mine in east-central Texas (USA)显示文摘 | Skousen J G Call C A Knight R W | 1990 | South-western Naturalist1990，35，： | 1 |
| 15 | Two-dimensional electrophoretic analysis of spore proteins of the microsporidia显示文摘 | Langley P C Call J A Somberg E W | 1987 | J Parasitol1987，73，5： | 1 |
| 16 | Purification, serology, and particle morphology of two russet crack strains of sweet potato feathery mottle virus 显示文摘 | Call B B Moyer J W | 1981 | Phytopathology1981，71，： | 1 |
| 17 | Fissuring of the posterior annulus fibrosus in the lumbar spine显示文摘 | Park W M Mc Call I W O′Brien J P | 1979 | Br J Radiol1979，52，617： | 1 |
| 18 | Identification of two sweet potato feathery mottle virus strains in North Carolina显示文摘 | Moyer J W Call B B | 1980 | Plant Disease1980，64，： | 1 |
| 19 | Postpartum changes in ute- rus and blood of ewes during the anoestrous season显示文摘 | FOOTE W C CALL J W | 1969 | Journal of Animal Science1969，29，： | 1 |
| 20 | Natural revegetation of an unreclaimed lignite surface mine in east central Texas (USA) 显示文摘 | Skousen J G Call C A Knight R W | 1990 | Southwestern Naturalist1990，35，： | 1 |
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