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| 1 | H pylori infection and systemic antibodies to CagA and heat shock protein 60 in patients with coronary heart disease显示文摘AIM: To determine the overall prevalence of H pylori and CagA positive H pylori infection and the prevalence of other bacterial and viral causes of chronic infection in patients with coronary heart disease (CHD), and the potential role of anti-heat-shock protein 60 (Hsp60) anti- body response to these proteins in increasing the risk of CHD development. METHODS: Eighty patients with CHD and 160 controls were employed. We also compared the levels of anti- heat-shock protein 60 (Hsp60) antibodies in the two groups. The H pylori infection and the CagA status were determined serologically, using commercially available enzyme-linked immunosorbent assays (ELISA), and a Western blotting method developed in our laboratory. Systemic antibodies to Hsp60 were determined by a sandwich ELISA, using a polyclonal antibody to Hsp60 to sensitise polystyrene plates and a commercially available human Hsp60 as an antigen. RESULTS: The overall prevalence of H pylori infec- tion was 78.7% (n = 63) in patients and 76.2% (n = 122) in controls (P = 0.07). Patients infected by CagA- positive (CagA+) H pylori strains were 71.4% (n = 45) vs 52.4% of infected controls (P = 0.030, OR = 2.27). Sys-temic levels of IgG to Hsp60 were increased in H pylori- negative patients compared with uninfected controls (P < 0.001) and CagA-positive infected patients compared with CagA-positive infected controls (P = 0.007). CONCLUSION: CagA positive H pylori infection may concur to the development of CHD; high levels of anti- Hsp60 antibodies may constitute a marker and/or a con- comitant pathogenic factor of the disease. | Cristina Lenzi Alberto Palazzuoli Nicola Giordano Giuliano Alegente Catia Gonnelli Maria Stella Campagna Annalisa Santucci Michele Sozzi Panagiotis Papakostas Fabio Rollo Ranuccio Nuti Natale Figura | 2006 | World Journal of Gastroenterology2006，12，48： | 23 |
| 2 | Relation of Plasma Brain Natriuretic Peptide Levels in Non–ST-Elevation Coronary Disease and Preserved Systolic Function to Number of Narrowed Coronary Arteries显示文摘 | Alberto Palazzuoli Luigi Gennari Paolo Calabria Ilaria Quatrini Lucia Vecchiato Vincenzo De Paola Maria Stella Campagna Vincenzo Palazzuoli Ranuccio Nuti | 2005 | The American Journal of Cardiology2005，，12： | 2 |
| 3 | The effects of short-vs, long-bout exercise on mood, VO2max, and percent body fat显示文摘 | Osei-Tutu K B Campagna P D | 2005 | Preventive Medicine2005，40，1： | 1 |
| 4 | Mechanisms of general anesthesia:from molecules to mind显示文摘 | Mashour GA Forman SA Campagna JA | 2005 | Best Pract Res Clin Anaesthesiol2005，19，3： | 1 |
| 5 | The emerging phenome- non of electronic cigarettes 显示文摘 | Caponnetto P Campagna D Papale G | 2012 | Expert Rev Respir Med2012，61，： | 1 |
| 6 | An environmentally relevant mixture of organochlorines, their metabolites and effects on preimplantation development of porcine embryos显示文摘 | Campagna C Ayotte P Sirard MA | 2008 | Reprod Toxicol2008，25，3： | 1 |
| 7 | Usefulness of alpha - fetoprotein in the diagnosis of hepatocelular carcinoma显示文摘 | Soresi M Magliarisi C Campagna P | 2003 | Anticancer Res2003，23，2： | 1 |
| 8 | Mechanisms of actions of inhaled anesthetics显示文摘 | Campagna JA Miller KW Foman SA | 2003 | N Engl J Med2003，348，21： | 1 |
| 9 | Diabetes: A oornrnon, growing, serious, costly, and potentially preventable public health problem 显示文摘 | Venkat Narayan KM Gregg EW Fagot - Campagna A | 2000 | Diabetes Res Clin Pract2000，50，2： | 1 |
| 10 | Mechanisms of actions of inhaled anesthetics显示文摘 | Miller KW Forman SA | 2003 | N Engl J Med2003，384，21： | 1 |
| 11 | Usefulness of alpha - fetoprotein in the diagnosis of hepatocellular carcinoma显示文摘 | Soresi M Magliarisi C Campagna P | 2003 | Anticancer Res2003，23，： | 1 |
| 12 | Clinical relevance of the Bezold-Jariseh reflex显示文摘 | Campagna JA Carter C | 2003 | Anesthesiology2003，98，5： | 1 |
| 13 | Mechanisms actions of in- haled anesthetics显示文摘 | Campagna JA Miller KW Forman SA | 2003 | N Engl J Med2003，348，21： | 1 |
| 14 | Mechanisms of actions of in-haled anesthetics 显示文摘 | Campagna JA Miller KW Forman SA | 2003 | N Engl J Med2003，348，： | 1 |
| 15 | Intraoperative ultrasonography during percutaneous Achilles tendon repair显示文摘 | Soubeyrand M Serra-Tosio G Campagna R | | 0，，12： | 1 |
| 16 | Alveolar epithelial barrier and acute lung injury显示文摘 | MATTHAY M A FOLKESSON H G CAMPAGNA A | 1993 | New Horiz1993，1，4： | 1 |
| 17 | Circulating gastrin and ghrelin levels in patients with colorectal cancer: Correlation with tumour stage, Helicobacter pylori infection and BMI显示文摘 | V. D’Onghia R. Leoncini R. Carli A. Santoro S. Giglioni F. Sorbellini G. Marzocca A. Bernini S. Campagna E. Marinello D. Vannoni | 2006 | Biomedicine & Pharmacotherapy2006，，2： | 1 |
| 18 | Mechanisms of actions of inhaled anesthetics 显示文摘 | Campagna JA Miller KW Forman SA | 2003 | N Engl J Med2003，348，10： | 1 |
| 19 | Usefulness of alpha fetoprotein in the diagnosis of hepatocellular carcinoma 显示文摘 | Soresi M Magliarisi C Campagna P | 2003 | Antlcancer Res2003，23，2： | 1 |
| 20 | Diabetic retinopathy and pregnancy 显示文摘 | Peseosolido N Campagna O Barbato A | 2014 | Int Ophthalmol2014，34，4： | 1 |
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