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| 1 | 口服非洲刺李后人的血清对不同良性前列腺细胞的生物效应显示文摘非洲刺李(太得恩。)是一种普遍用于治疗有症状良性前列腺增生的草药。该药物的活性物质还没有被鉴定出来,因此,确定其血药浓度是不可能的。对该药的疗效目前存在一些争议,因而我们决定用摄入和未摄入非洲刺李的人的血清在体外处理前列腺细胞,观察其对前列腺细胞生长的作用。我们使用的是原代培养和器官培养的良性成纤维(WPMY)前列腺细胞和上皮(PNT2)前列腺细胞。我们也使用了新鲜的良性前列腺组织。研究发现,摄入非洲刺李的人血清可以减少原代培养细胞、器官培养细胞以及WPMY细胞的增殖,但不影响PNT2细胞的增殖。我们还利用AffymetrixHG.U1332.0PLUS芯片分析了处理血清对WPMY细胞基因表达的影响。转录子分析结果显示参与肿瘤抑制通路的多个基因的表达发生了上调,而一些参与炎症及氧化应激通路的基因表达发生了下调。口服非洲刺李可使药物的活性物质达到足够的血清水平,从而抑制成纤维前列腺细胞的增殖。此抑制作用与转录子的改变有关。 | Stephane Larre Philippe Camparo Eva Comperat Delphine Boulbes Mohammed Haddoum Sylvain Baulande Pascal Soularue Pierre Costa Olivier Cussenot | 2012 | Asian Journal of Andrology2012，14，3： | 2 |
| 2 | Splenic metas- tases : clinicopathologic presentation, differential diagnosis, and pathogenesis 显示文摘 | Comprrat E Bardier-Dupas A Camparo P | 2007 | Arch Pathol Lab Med2007，131，6： | 1 |
| 3 | Differential expression of cathepsin K in neoplasms harboring TFE3 gene fusions 显示文摘 | Martignoni G Gobbo S Camparo P | 2011 | Mod Pathol2011，24，10： | 1 |
| 4 | Renal translocation carcinomas:clinicopathologic,immunohistochemical,and gene expression profiling analysis of 31 cases with a review of the literature显示文摘 | Camparo P Vasiliu V Molinie V | 2008 | Am J Surg Pathol2008，32，5： | 1 |
| 5 | Interviewing children about real and fictitious events: revisiting the narrative e- laboration procedure 显示文摘 | Camparo L B Wagner J T Saywitz K J | 2001 | Law and human behavior2001，25，1： | 1 |
| 6 | Effects of power on electron den sity and temperature, neutral temperature, and Te fluctuations in an inductively coupled plasma显示文摘 | Camparo James Fathi Gilda | 2009 | Journal of Applied Physics2009，105，10： | 1 |
| 7 | Transcription factor E3 and transcription factor EB renal cell carcinomas: clinical features, biological behavior and prognostic factors 显示文摘 | Malouf G G Camparo P Molini6 V | 2011 | J Urol2011，185，1： | 1 |
| 8 | Differential expression of cathepsin K in neoplasms harboring TFE3 gene fusions 显示文摘 | Martignoni G Gobbo S Camparo P | 2011 | Mod Pathol2011，24，10： | 1 |
| 9 | Variation in reporting of cancer extent and benign histology in prostate biopsies among European pathologists 显示文摘 | Berney DM Algaba F Camparo P | 2014 | Virehows Arehiv2014，464，： | 1 |
| 10 | Targeted a gents in metastatic Xpll translocation/TFE3 gene fusion renal cell carcinoma (RCC) : a report from the Juvenile RCC Network 显示文摘 | MALOUF G G CAMPARO P OUDARD S | 2010 | Ann Oncol2010，21，9： | 1 |
| 11 | Soli- tary fibrous tumor of the kidney显示文摘 | DURAND X DELIGNE E CAMPARO P | 2003 | Prog Urol2003，13，： | 1 |
| 12 | Aurora-A/STK-15 is a predictive factor for recurrent behaviour in non-invasive bladder carcinoma:a study of 128 cases of non-invasive neoplasms显示文摘 | Comperat E Camparo P Haus R | 2007 | Virchows Arch2007，450，4： | 1 |
| 13 | Solitary fibrous tumor of the kidney显示文摘 | Durand X Deligne E Camparo P | 2003 | Prog Urol2003，13，3： | 1 |
| 14 | Expression of follicle- stimulating hormone receptor in tumor blood vessels 显示文摘 | Radu A Pichon C Camparo P | 2010 | N Engl J Med2010，363，17： | 1 |
| 15 | Transcription factor E3 and transcription factor EB renal cell carcinomas:clinical features, biological behavior and prognostic factors 显示文摘 | Malouf GG Camparo P Molinie V | 2011 | J Urol2011，185，1： | 1 |
| 16 | Renal translocation carcinomas: clinicopathologic, immunohistochemical, and gene expression profiling analysis of 31 cases with a review of the literature显示文摘 | CAMPARO P VASILIU V MOLIN1E V | 2008 | Am J Surg Pathol2008，32，5： | 1 |
| 17 | Spin destruction in collisions between cesium atomic显示文摘 | Bhaskar N D Pietras J Camparo J | 1980 | Phys Rev Lett1980，44，： | 1 |
| 18 | Penile cancer in 2010:updata from the Oneology Committee of the French Association of Urology:external genital organs group (CCAFU-OGE) 显示文摘 | Souillac I Avances C Camparo P | 2011 | Prog Urol2011，21，13： | 1 |
| 19 | SALIA is a useful marker in the diag nostic work-up of germ cell tumors in extra-testicularlocations显示文摘 | Camparo P Comperat EM | 2013 | Virchows Arch2013，462，3： | 1 |
| 20 | Renal translocation carcino- mas: clinicopathologic, immunohistochemieal, and gene expression profiling analysis of 31 cases with a review of the literature显示文摘 | Camparo P Vasiliu V Molinie V | 2008 | Am J Surg Pathol2008，32，5： | 1 |
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