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| 1 | Inflammatory bowel disease in an underdeveloped region of Northeastern Brazil显示文摘AIM: To evaluate the demographic characteristics and clinical phenotypes of inflammatory bowel disease(IBD) in a geographic area in Northeastern Brazil.METHODS: This retrospective study was conducted at the Hospital of the Federal University of Piauí in Northeastern Brazil. Demographic characteristics and clinical phenotypes of IBD were analyzed in relation to the time of diagnostic confirmation, which was defined as the date of disease onset. Data were collected between January 2011 and December 2012 and included all census patients 18 years of age or older during that period for whom there was diagnostic confirmation of Crohn's disease(CD), ulcerative colitis(UC), or unclassified colitis according to the Montreal criteria. We also analyzed the period of time between the onset of clinical manifestations and the diagnosis of IBD(delay in the diagnosis). Statistical analyses included means and standard deviations for numeric variables and the Pearson χ2 adherence test for nominal variables. The annual index occurrence and overall prevalence of IBD at our institution were also calculated, with P values < 0.05 indicating statistical significance. This study was approved by the Institutional Ethics and Research Committee.RESULTS: A total of 252 patients with IBD were included, including 152(60.3%) UC patients and 100(39.7%) CD patients. The clinical and demographic characteristics of all patients with IBD showed a female to male ratio of 1.3:1.0 and a mean age of35.2(SD = 14.5) years. In addition, the majority of patients were miscegenated(171, 67.9%), had received higher education(157, 62.4%), lived in urban areas(217, 86.1%), and were under the age of 40 years(97, 62.5%). For patients with CD, according to the Montreal classification, the predominant features present from the onset of disease were an age between 17 and 40 years(A2); colonic disease location(L2); and nonstricturing, nonfistulizing disease behavior(B1). However, approximately one-quarter of all CD patients demonstrated perineal involvement. We also observed considerable delay in the diagnosis of IBD throughout the entire study period(mean = 35.5 mo). In addition, the annual index occurrence rose from 0.08 to 1.53 cases/105 inhabitants/year during the study period, and the prevalence rate was 12.8 cases/105 inhabitants in 2012. Over the last two decades, there was a noted increase in the frequency of IBD in the study area.CONCLUSION: In this study, there was a predominance of patients with UC, young people under 40 years of age, individuals with racial miscegenation, and low annual incomes. | José Miguel Luz Parente Claudio Saddy Rodrigues Coy Viriato Campelo Mírian Perpétua Palha Dias Parente Leonardo Araújo Costa Renata Mendes da Silva Celso Stephan José Murilo Robilotta Zeitune | 2015 | World Journal of Gastroenterology2015，21，4： | 3 |
| 2 | Liquid phase hydrogenation of 1-alkenes over Rh/AlPO4 and Rh/sepiolite catalysts显示文摘 | Cabello J A Campelo J M Garcia A | 1993 | J Mol Catal1993，78，： | 1 |
| 3 | Studies of catalyst deactivation in methanol conversion with high medium and small pore silicoaluminophosphates显示文摘 | Campelo J M Lafont F Marinas J M | 2000 | Appl Catal A2000，192，： | 1 |
| 4 | Studies of catalyst deactivation in methanol conversion with high medium and small pore silicoaluminophosphates显示文摘 | Campelo J M Lafont F Marinas J M | 2000 | Appl Catal A2000，192，1： | 1 |
| 5 | Design and development of catalysts for biomass-to-liquid-Fischer- Tropsch (BTL-FT) processes for biofuels production显示文摘 | Luque R de la Osa A R Campelo J M | 2012 | Energy & Environmental Science2012，5，1： | 1 |
| 6 | Catechol O-methylation with dimethyl carbonate over different acid-base catalysts 显示文摘 | Luque R Campelo J M Conesa T D | 2006 | New Journal of Chemistry2006，30，： | 1 |
| 7 | Comparison of the activity and selectivity of Pt/SAPO-5 and Pt/SAPO-11 in n-hexane and n-heptane hydroconversion显示文摘 | Lafont F Marinas J M | 1997 | Appl Catal A:1997，152，1： | 1 |
| 8 | Biofuels: a technological perspective 显示文摘 | LUQUE R HERRERO-DAVILA L CAMPELO J M | 2008 | En- ergy Environ Sci2008，5，1： | 1 |
| 9 | Knoevenagel condensation in heterogeneous phase using A1PO4 - AlzOs as a new catalyst显示文摘 | Cabello J A Campelo J M Garcia A | 1984 | J Org Chem1984，49，26： | 1 |
| 10 | Acidity and catalytic activity of AlPO4-B2O3 and Al2O3-B2O3 (5-30% B2O3) systems prepared by impregnation显示文摘 | BAUTISTA F M CAMPELO J M GARCIA A LUNA D MARINAS J M MORENO M C ROMERO A A | 1998 | Appl Catal A: Gen1998，170，1： | 1 |
| 11 | Efficacy of rituximab in an aggressive form of multicentric Castleman disease associated with immune phenomena 显示文摘 | Ocio EM Sanchez - Guijo FM Diez - Campelo M | 2005 | Am J Hematol2005，78，： | 1 |
| 12 | A computational study of global algorithms for linear bilevel programming显示文摘 | de Saboia C H M Campelo M Scheimberg S | 2004 | Numerical Algorithms2004，35，24： | 1 |
| 13 | Morphometric study on the anatomy of the fetal cricoid cartilage and comparison between its inner diameter and endotracheal tube sizes显示文摘 | LIMA L F NITA L M CAMPELO V E | 2008 | Ann Otol Rhinol Laryngol2008，117，10： | 1 |
| 14 | Vanadium oxides supported on TiO2 - Sepiolite and sepiolite : Preparation, structural and acid characterization and catalytic behaviour in selective oxidation of toluene 显示文摘 | BAUTISTA F M CAMPELO J M LUNA D | 2007 | Appl Catal A Gen2007，325，2： | 1 |
| 15 | Influence of surface support properties on the liquid-phase selective hydrogenation of phenylacetylene on supported nickel catalysts显示文摘 | Bautista F M Campelo J M Garcia A | 1998 | Catalysis Letters1998，52，： | 1 |
| 16 | Characterization of calcium oxide catalysts from natural sources and their application in the transesterifieation of sunflower oil 显示文摘 | CORREIA L M SABOYA R M A DE SOUSA CAMPELO N | 2014 | Bioresource Technology2014，151，： | 1 |
| 17 | Alkylation of phenol with dimethyl carbonate over ALPO4, AL203 and AIPO4-AL203 catalysts显示文摘 | Bautista F M Campelo J M Garcia A | 1998 | Reaet Kinet Catal Lett1998，63，： | 1 |
| 18 | Comparison of the acrivity and selectivity of Pt/SAPO-5 and Pt/SAPO-11 in n-hexane and n- heptane hydroconvertion显示文摘 | CAMPELO J M LAFONT F MARINAS J M | 1997 | Appl Catal1997，152，1： | 1 |
| 19 | Catechol o-methylation with dimethyl carbonate over different acid-base catalysts显示文摘 | Luque R Campelo J M ConesaT D | 2006 | New Journalofthe ChemicalSociety2006，30，： | 1 |
| 20 | Hydroconversion of n-dodecane over Pt/SAPO-11 catalyst显示文摘 | CAMPELO J M LAFONT F MARINAS J M | 1998 | Appl Catal1998，170，1： | 1 |
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