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| 1 | Impaired auditory sensorimotor gating: An animal model of schizophrenia显示文摘Establishment of animal models of schizophrenia is critical for both understanding the mechanisms underlying this severe mental disease and developing new antipsychotics. This paper starts from the theoretical root of sensory gating, the 損rotection-of-processing?theory, then thoroughly describes the representative studies over the past decade on the mechanism underlying prepulse inhibition and on those underlying modulation of prepulse inhibition, which is the normal startle suppression caused by the weak stimulus preceding the intense startling stimulus. The main methods for inducing prepulse inhibition deficits in experimental animals include: ⅰ) modulations of neuro- transmission that are closely associated with schizophrenia; ⅱ) focal lesions or pharmacological manipulations of brain structures in the cortico-striato-pallido-pontine circuit; and ⅲ) maternal deprivation or social isolation. Six essential topics for studies in modeling schizophrenia are suggested at the last part of this review. | LI Liang & SHAO Feng 1. Department of Psychology, Peking University, Beijing 100871, China 2. Centre for Research on Biological Communication Systems, University of Toronto at Mississauga, Mississauga, Ontario L5L 1C6, Canada | 2003 | Chinese Science Bulletin2003，48，19： | 5 |
| 2 | SOURCE RADIATION AND RESPONSES OF WAVE PROPAGATION显示文摘Recordings of seismic waves propagating from earthquake source to a station at the earth’s surface are a system response function. The convolution operator in time domain can be simplified as a multiplication operator in frequency domain. We discuss in frequency domain the separation of source, path and site effects for global scaling of earthquake source radiation. Also discussed are source scaling model, faulting mechanism, and the H/V inversion problems with crustal and near surface structures. Gross features of apparent source spectra appear to be not much region dependent although there may be difference between tectonic styles within a region of tectonic mixture for which we need further study as data accumulate. Vertical spectra may be a better approach to approximate source radiation, as it has less crustal amplification effects than horizontal spectra. The H/V ratio is evidently a comprehensive indicator of amplification effects from near surface to deep structure. This gives it potential as an inversion tool to deduce site crustal structure. | CHEN Sheng zao 1 and Gail M Atkinson 2 (1. Geomatrix Consultants, Inc., 2101 Webster St., 12 th Floor, Oakland, CA 94612, USA, formerly at Dept. Earth Sciences & Ottawa Carleton Geoscience Center, Carleton University, Ottawa, Canada 2. Dept. Ea | 2001 | Geotectonica et Metallogenia2001，25，1： | 2 |
| 3 | Long term propofol infusion for refractory postoperative nausea:a case report with quantitative propofol analysis显示文摘 | Sculman SR Rockett CB Canada AT | 1995 | Anesth Analg1995，80，： | 1 |
| 4 | Long teem propofol infusion for refractory postoperative nausea:a case report wwith quantitative propofol analysis显示文摘 | Sculman SR Rocker CB Canada AT et a1 | 1995 | Anesth Analg1995，80，： | 1 |
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