| 1 | Comparison of intravitreal bevacizumab and triamcinolone acetonide theraphies for diffuse diabetic macular edema显示文摘AIM: To compare therapeutic effects of intravitreal triamcinolone acetonide(IVTA) versus intravitreal bevacizumab(IVB) injections for bilateral diffuse diabetic macular edema(DDME). METHODS: Forty eyes of 20 patients with bilateral DDME participated in this study. For each patient, 4 mg/0.1 m L IVTA was injected to one eye and 2.5 mg/0.1 m L IVB was injected to the other eye. The effects of injection for diabetic macular edema(DME) were evaluated using best-corrected visual acuity(BCVA), central macular thickness(CMT) by optical coherence tomography(OCT)and intraocular pressure(IOP) by applanation tonometer.Patients underwent eye examinations, including BCVA,CMT, and IOP at pre-injection, 1, 4, 8, 12 and 24 wk after injection. During the follow-up, second injections were performed to eyes which have CMT greater than 400 μm at 12 wk for salvage therapy.RESULTS: BCVA(logarithm of the minimum angle of resolution) at pre-injection, 1, 4, 8, 12 and 24 wk after injection was 0.71 ±0.19, 0.62 ±0.23, 0.63 ±0.12, 0.63 ±0.13,0.63±0.14 and 0.61±0.24 in the IVTA group and 0.68±0.25,0.61 ±0.22, 0.60 ±0.24, 0.62 ±0.25, 0.65 ±0.26 and 0.59 ±0.25 in the IVB group, respectively. CMT(μm) at pre-injection,1, 4, 8, 12 and 24 wk after injection was 544 ±125, 383±96,335 ±87, 323 ±87, 333 ±92, 335 ±61 in the IVTA group and514 ±100, 431 ±86, 428 ±107, 442 ±106, 478 ±112, 430 ±88 in the IVB group respectively. Reduction ratios of mean CMT were 29% at 1wk, 38% at 4wk, 40% at 8wk, 38% at12 wk, and 38% at 24 wk in the IVTA group. Second IVTA injections were performed to the 6 eyes(30%) at 12 wk.Reduction ratios of mean CMT were 16% at 1wk, 17% at4wk, 14% at 8wk, 7% at 12 wk, and 16% at 24 wk in the IVB group. Second IVB injections were performed to the15 eyes(75%) at 12 wk.CONCLUSION: This study showed earlier and more frequent macular edema recurrences in the eyes treated with bevacizumab compared with the ones treated with triamcinolone acetonide. Triamcinolone acetonide was found to provide more efficient and long-standing effect in terms of reducing CMT compared with the bevacizumab. | Sibel Aksoy Gursel Yilmaz Imren Akkoyun Ayse Canan Yazici | 2015 | International Journal of Ophthalmology(English edition)2015,8,3: | 6 |
| 2 | Elemental Analysis of Tea Leaves (Camellia Sinensis) and Their Own Soils at Eastern Black Sea Region in Turkey显示文摘People consume tea brewed from the leaves of the Camellia sinensis plant for about 50 centuries. Health benefits of the tea have been investigated for about three decades. Especially green tea shows antitoxic and lots of properties with its determined ingredients. Turkey is not only the one of the best consumer and but also good producer of the tea as being 5 th producer all over the world. It grows eastern region of the Turkey and high quality tea is imported and exported. To have quality tea, grooving soils are also crucial. In the current research, Tea leaves and their own grown soils were collected from 20 stations where the most tea producer cities as Trabzon, Rize and Artvin tea fields of the eastern of Black Sea Region in Turkey. The cultivated tea and their own grown soil samples were analysed by using EDXRF Spectrometry. In the soil samples, the elements Mg, Al, Si, P, S, K, Ca, Ti, V, Cr, Mn, Fe, Ni, Cu, Zn, Sr, Ba, Pb on percent level and the elements Mg, Al, Si, P, Cl, K, Ca, Ti, Mn, Fe, Ni, Cu, Zn and Sr in the tea leaves were detected by using SKRAY 3600-EDXRF.and also the obtained data were evaluated with the Kriging interpolation of geostatistical method. Element content were investigated in the soil and tea samples according to the geological situations and also the relation of elemental difference between the tea and the own grown soil. Pb/Zn ratio was also anaysed in the samples. | Canan Aksoy Hatice Kabaoglu G khan Apayd n Aziz Safi Engin T rasoglu | 2020 | 光谱学与光谱分析2020,40,4: | 0 |