|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Estrogens in males: what have we learned in the last 10 years?显示文摘This review focuses on the role of estrogen in men, mainly in male reproduction. The continuing increase in data obtained, and recent discoveries in this area will enable a better understanding of male physiology; these, in turn, will have important clinical implications. | Vincenzo Rochira Antonio R. M. Granata Bruno Madeo Lucia Zirilli Giuseppina Rossi Cesare Carani | 2005 | Asian Journal of Andrology2005，7，1： | 15 |
| 2 | 湖南汉族1型糖尿病患者杀伤细胞免疫球蛋白样受体及其配体基因多态性显示文摘目的探讨杀伤细胞免疫球蛋白样受体(KIR)基因和KIR配体人类白细胞抗原-C(HLA—C)基因的多态性与1型糖尿病(T1DM)的关系。方法采用聚合酶链反应-序列特异性引物技术(PCR—SSP),对湖南汉族180例TIDM患者和199例正常对照者KIR基因、HIA—C基因进行检测和分析。结果(1)与正常对照相比,T1DM组KIR2DL1(98.9%比92.0%,OR=7.78,P=0.002)、3DL1(94.3%比86.4%,OR=2.67,P=0.009)和2DS4(83.9%比70.9%,OR=2.14,P=0.003)基因频率增高;(2)T1DM组和正常对照组HIJA—c(HIJA—C1、HLA—C2)基因频率差异无统计学意义,但T1DM组HLAC1+/C2+(3.9%比9.6%,OR=0.38,P=0.03)基因频率降低;(3)与正常对照组相比,T1DM组KIR/HLA-C基因组合中KIR2DL1-/HLA-C2-(0.6%比6.0%,OR=0.087,P=0.003)和KIR2DS1-/HLA—C2-(53.3%比64.8%,OR=0.62,P=0.023)基因频率降低。结论KIR基因多态性和KIR/HLA—C基因组合与T1DM发病相关。 | 谭愈昱 林健 黄干 唐炜立 Saikiran K Sedimbi Carani B Sanjeevi 周智广 | 2010 | 中华医学杂志2010，90，4： | 5 |
| 3 | Diabetes--Role of epigenetics,genetics,and physiological factors显示文摘Cells of organ systems are endowed with a relatively similar genome while epigenome niches keep varying chronologically and defined explicitly in the respective tissues.The genome of an individual is always influenced by parental,embryonic,tissue-specific,and environmental epigenomes and the same must have been the possible reason for invariable inquiries relating to familial,environmental and life style patterns in the preliminary investigations of diabetic complications.Unprecedented methylation of lysine residues of histones and cytosines of CpG islands of promoter DNA impede the transcription of genes and homocysteine is the metabolic key player of methyl groups.Gck and COX7A1 are the 2 examples in the present review to elucidate the epigenetic influence on the onset of diabetes.miRNAs are additional promising cellular components influencing both at transcriptional and translational levels and promoting either in favour or against(i.e.,feed back) TFs,signaling factors and proteins through their pliotropic effects and thus are reported to regulate cellular physiology.miR-124a and miR-9 are primarily endemic to nervous tissue and they are now being exploited in islets for their function in executing exocytosis of insulin,which of course is one of the fundamental canons of diabetes.miR-375 persuades beta cells for glucose-induced insulin gene expression.The current approach to evaluate the constellation of genes and their products involved in diabetes in huge number of samples through GWA studies may unravel intricacies involved in the management of diabetes and its associated consequences. | Sreerama Krupanidhi Saikiran K. Sedimbi Ganesan Vaishnav Sreerama Sai Madhukar Carani B. Sanjeevi | 2009 | 中南大学学报(医学版)2009，34，9： | 3 |
| 4 | Muscle fiber type characterization and myosin heavy chain (MyHC) isoform expression in Mediterranean buffaloes显示文摘 | Francisco C L Jorge A M Carani F R | 2011 | Meat Science2011，88，3： | 1 |
| 5 | Efficacy and safety of trabeculectomy with mitomycin C for childhood glaucoma:a study of results with long-term follow-up显示文摘 | Giampani J Jr Borges-Giampani AS Carani JC | | 0，，： | 1 |
| 6 | The change in axial length in the pseudophakic eye compared to the unoperated fellow eye in children with bilateral cataracts显示文摘 | Tartarella MB Carani JC Scarpi MJ | 2014 | J AAPOS2014，18，2： | 1 |
| 7 | Multicenter study on the prevalence of sexual symptoms in male hypoand hyperthyroid patients 显示文摘 | Carani C | 2005 | J Clin Endocrinol Metab2005，90，12： | 1 |
| 8 | The CD47 pathway is deregulated in human immune thrombocytopenia显示文摘 | Carani L Sollazzo D Ricci F | | 0，，04： | 1 |
| 9 | Effect of testoesterone and estradiol in a man with aromatease deficiency: Brief report 显示文摘 | Carani C Qin K Simoni M | 1997 | N Eagl Med1997，337，： | 1 |
| 10 | Multicenter study on the Prevalence of Sexual Symptoms in Male Hypo - and Hyperthy- roid Patients显示文摘 | Carani C Isidori AM Genker A | 2005 | Journal of Clinical Endocrinology and Metab- olism2005，90，： | 1 |
| 11 | Estrogen resistance and aromamse deficiency in humans显示文摘 | Carani C Fabbi M Zirilli L | 2002 | J Soc Biol2002，196，3： | 1 |
| 12 | Effect of testosterone and estradiol in a man with aromatase deficiency 显示文摘 | Carani C Qin K Simoni M | 1997 | New England Journal of Medicine1997，337，2： | 1 |
| 13 | Screening for deletion of Y chromosome involving the DAZ (Deleted in Azoospermia)gene in azoospermia and severe oligozoospermia显示文摘 | Simoni M Carani C Gromoll J | 1997 | Fertil Steril1997，67，： | 1 |
| 14 | Muhicenter study on the prevalence of sexual symptoms in male hypo-and hyperthyroid patients显示文摘 | Carani C Isidofi AM Granata A | 2005 | J Clin Endocr Metab2005，90，12： | 1 |
| 15 | High-Intensity Resistance Training with Insufficient Recovery Time Between Bouts Induce Atrophy and Alterations in Myosin Heavy Chain Content in Rat Skeletal Muscle显示文摘 | De Souza RWA Aguiar AF Carani FR | 2011 | Anat Rec(Hoboken)2011，294，8： | 1 |
| 16 | Effects of androgen treatment in impotent men with normal and low levels of free testosterone显示文摘 | Carani C Zini P Baldin A | 1990 | Arch Sex Behav1990，19，： | 1 |
| 17 | Further studies on the hypothalamic-pituitary-gonadalilinction in man显示文摘 | Celanic MF Carani C | 1984 | Pharmacol Res Conmun1984，16，12： | 1 |
| 18 | Further studies on the hypothalamic- pituitary- gonadal function in man显示文摘 | Celanic MF Carani C | 1984 | Pharmacol Res Conmun1984，16，12： | 1 |
| 19 | The CD47 pathwayis deregulated in human immune thrombocytopenia显示文摘 | CARANI L SOLLAZZO D RICCI F | 2011 | Exp Hema-tol2011，39，4： | 1 |
| 20 | Effect of testosterone and estradiol in a man with aromatase deficiency显示文摘 | Carani C Qin K Simoni M | 1997 | N Engl J Med1997，337，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员