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| 1 | Pandemic influenza 2009: Impact of vaccination coverage on critical illness in children, a Canada and France observational study显示文摘AIM To study the impact of vaccination critical illness due to H1N1pdm09, we compared the incidence and severity of H1N1pdm09 infection in Canada and France.METHODS We studied two national cohorts that included children with documented H1N1pdm09 infection, admitted to a pediatric intensive care unit(PICU) in Canada and in France between October 1, 2009 and January 31, 2010.RESULTS Vaccination coverage prior to admission to PICUs was higher in Canada than in France(21% vs 2% of children respectively, P < 0.001), and in both countries, vaccination coverage prior to admission of these critically ill patients was substantially lower than in the general pediatric population(P < 0.001). In Canada, 160 children(incidence = 2.6/100000 children) were hospitalized in PICU compared to 125 children(incidence = 1.1/100000) in France(P < 0.001). Mortality rates were similar in Canada and France(4.4% vs 6.5%, P = 0.45, respectively), median invasive mechanical ventilation duration and mean PICU length of stay were shorter in Canada(4 d vs 6 d, P = 0.02 and 5.7 d vs 8.2 d, P = 0.03, respectively). H1N1pdm09 vaccination prior to PICU admission was associated with a decreased risk of requiring invasive mechanical ventilation(OR = 0.30, 95%CI: 0.11-0.83, P = 0.02).CONCLUSION The critical illness due to H1N1pdm09 had a higher incidence in Canada than in France. Critically ill children were less likely to have received vaccination prior to hospitalization in comparison to general population and children vaccinated had lower risk of ventilation. | Olivier Fléchelles Olivier Brissaud Robert Fowler Thierry Ducruet Philippe Jouvet the Pediatric Canadian Critical Care Trials Group H1N1 Collaborative and Groupe Francophone de Réanimation et Urgences Pédiatriques | 2016 | World Journal of Clinical Pediatrics2016，5，4： | 2 |
| 2 | Electrostatic wear sensing of ceramic-steel lubricated contacts显示文摘 | WANG L WOOD R J K CARE I et ai | 2003 | Tribology Series2003，43，： | 1 |
| 3 | Mutans streptococci anddental caries prevalence in a group of Latvian preschool chil-dren 显示文摘 | Kohler B Bjarnason S Care R | 1995 | EurJOral Sci1995，103，4： | 1 |
| 4 | Seismic monitoring of a CO2 flood in a carbonate reservoir:A rock physics study显示文摘 | Wang Z Cares M E Langan R T | 1998 | Geophys- ics1998，63，5： | 1 |
| 5 | Isolation of the bovine and human genes for Mtillerian inhibiting substance and expression of the human gene in animal cells显示文摘 | Care RL Mattaliano R J Hession C | 1986 | Cell1986，45，5： | 1 |
| 6 | Growth factors/cytokines/de- fensins and apoptosis in periodontal pathologies 显示文摘 | Laurina Z Pilmane M Care R | 2009 | Stoma- tologijia2009，11，2： | 1 |
| 7 | Protective Effects of Curcumin on Renal Oxidative Stress and Lipid Metabolism in a Rat Model of Type 2 Diabetic Nephropathy显示文摘 | Diagnosis and classifica- Diabetes Care 2013 36 Kim B H Lee E S Choi R | 2016 | Yon- sei Med J2016，57，3： | 1 |
| 8 | Humidification during invasive and noninvasive mechanical ventilation:2012显示文摘 | American Association for Respiratory Care Restrepo R D Walsh B K | 2012 | Respir Care2012，57，5： | 1 |
| 9 | Sexual transmis- sion of HIV显示文摘 | Royce R A Sefia A Cares W Jr Cohen M S | 1997 | N Engl J Med1997，336，： | 1 |
| 10 | C18 Extraction of atrazine from small water sample volumes显示文摘 | Shepherd T R Care J D | 1992 | AOAC Int1992，，75： | 1 |
| 11 | Mutans streptoeoeei and dental caries prevalence in a group of Latvian preschool children 显示文摘 | Kohler B Bjarnason S Care R | 1995 | Eur J Oral Sci1995，103，4： | 1 |
| 12 | Assessment and classification of can- cer pain显示文摘 | Hjermstad MJ Fainsinger R Kaasa S European Palliative Care Re- search CollaborativeCEPCRC) | 2009 | Quit Opin Support Palliat Care2009，3，1： | 1 |
| 13 | Nanoscale metallic iron for environmental remediation: prospects and limitations显示文摘 | Noubactep C Care S Crane R | 2012 | Water Air Soil Pollut2012，223，3： | 1 |
| 14 | Interleukin-6 increases insulin stimulated glucose disposal in humans and glucose uptake and fatty acid oxidation in vitro via AMP- activated protein kinase显示文摘 | Care A L Steinberg G R Macaulay S L | 2006 | Diabetes2006，55，： | 1 |
| 15 | Heterogeneity in R&D cooperation strategies显示文摘 | Belderbo R Caree M Diederen B | 2004 | Intemational Journal of Ind- ustrial Organization2004，22，8： | 1 |
| 16 | Bronchial emboization in the treatmanteof hemotysis 显示文摘 | Bustanmante M Care VR Agro R | 1998 | Arch Broncoponeumol1998，34，： | 1 |
| 17 | Jamming transition in a homogeneous one-dimensional system: The bus route mode 显示文摘 | O' loan O J Evans M R Cares M E | 1998 | Physical Review E1998，58，2： | 1 |
| 18 | Characterisation of genetic variation between Vitis vinifera cultivars from central Chile using RAPD and inter simple sequence repeat markers 显示文摘 | Herrera R Cares V Wilkinson M J | 2002 | Euphytica2002，124，： | 1 |
| 19 | Interleukin 10 regulates inflammatory cytokine synthesis to protect against lipopolysaceharide-induced abortion and fetal growth restriction in mice显示文摘 | Robertson S A Care A S Skinner R J | 2007 | Biol Reprod2007，76，5： | 1 |
| 20 | Characterisation of genetic variation between Vitis vinifera cultivars from central Chile using RAPD and inter-simple sequence repeat markers显示文摘 | HERRERA R CARES V WILKINSON M J | 2002 | Euphytica2002，124，： | 1 |
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